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Platelet Activating Factor
go.drugbank.com/drugs/DB02261ExperimentalCategories: P-glycoprotein inducers, P-glycoprotein substratesColforsin
go.drugbank.com/drugs/DB02587InvestigationalPotent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also...
Categories: P-glycoprotein inhibitorsDigoxigenin
go.drugbank.com/drugs/DB03671ExperimentalDigoxigenin is a cardenolide which is the aglycon of digoxin. Can be obtained by hydrolysis of digoxin or from Digitalis orientalis L. and Digitalis lanata Ehrh.
Categories: P-glycoprotein substratesBerberine
go.drugbank.com/drugs/DB04115ApprovedInvestigationalWithdrawnAn alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 InhibitorsQuercetin
go.drugbank.com/drugs/DB04216InvestigationalQuercetin is a flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP1A2 Inhibitors9-Deazaguanine
go.drugbank.com/drugs/DB04356ExperimentalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesN-Methyl-N-(Methylbenzyl)Formamide
go.drugbank.com/drugs/DB04379ExperimentalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 SubstratesChloramphenicol succinate
go.drugbank.com/drugs/DB07565ApprovedChloramphenicol succinate is an ester prodrug of chloramphenicol. Chloramphenicol is a bacteriostatic antibiotic. Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias. C...
Categories: P-glycoprotein substrates, P-glycoprotein substrates with a Narrow Therapeutic IndexParecoxib
go.drugbank.com/drugs/DB08439ApprovedInvestigationalParecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx). As it is inj...
Synonyms: N-((p-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)propionamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates