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Displaying results 141 - 150 of 367 in total
  1. Target

    Cocaine esterase

    go.drugbank.com/bio_entities/BE0004712
    EnzymeHumans

    Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine (PubMed:9169443). … Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (PubMed:9169443).

    Synonyms: Methylumbelliferyl-acetate deacetylase 2
  2. Target

    Solute carrier family 13 member 4

    go.drugbank.com/bio_entities/BE0010199
    TransporterHumans

    Sodium:sulfate symporter that mediates sulfate reabsorption in the high endothelial venules (HEV)

    Synonyms: Na(+)/sulfate cotransporter SUT-1
  3. Target

    Arylsulfatase

    go.drugbank.com/bio_entities/BE0001490
    TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

    Hydrolyzes the bond between sulfate and the aromatic ring in a compound such as 4-nitrocatechol sulfate.

    Synonyms: Aryl-sulfate sulphohydrolase
  4. Target

    Aggrecan core protein

    go.drugbank.com/bio_entities/BE0004104
    TargetHumans

    It binds avidly to hyaluronic acid via an N-terminal globular region

    Synonyms: Chondroitin sulfate proteoglycan 1, Chondroitin sulfate proteoglycan core protein 1
  5. Target

    Neurocan core protein

    go.drugbank.com/bio_entities/BE0004512
    TargetHumans

    May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid

    Synonyms: Chondroitin sulfate proteoglycan 3Function: calcium ion binding
  6. Target

    Calcineurin B homologous protein 1

    go.drugbank.com/bio_entities/BE0008693
    TargetHumans

    Inhibits both STK17B auto- and substrate-phosphorylations in a calcium-dependent manner … Inhibits NFAT nuclear translocation and transcriptional activity by suppressing the calcium-dependent calcineurin phosphatase activity.

    Synonyms: Calcium-binding protein CHP, Calcium-binding protein p22Function: calcium ion binding
  7. Target

    Lumican

    go.drugbank.com/bio_entities/BE0009066
    TargetHumans

    Synonyms: Keratan sulfate proteoglycan lumican
  8. Target

    Transient receptor potential cation channel subfamily V member 6

    go.drugbank.com/bio_entities/BE0005102
    TransporterTargetHumans

    The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification (PubMed:15184369). … Important for normal Ca(2+) ion homeostasis in the body, including bone and skin (By similarity).

    Synonyms: Calcium transport protein 1, Epithelial calcium channel 2Function: calcium channel activity
  9. Target

    Versican core protein

    go.drugbank.com/bio_entities/BE0004606
    TargetHumans

    May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid

    Synonyms: Chondroitin sulfate proteoglycan 2, Chondroitin sulfate proteoglycan core protein 2Function: calcium ion binding
  10. Target

    Syndecan-2

    go.drugbank.com/bio_entities/BE0002116
    TargetHumans

    Cell surface proteoglycan which regulates dendritic arbor morphogenesis

    Synonyms: Heparan sulfate proteoglycan core protein