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Displaying results 141 - 150 of 2763 in total
  1. Target

    Protein PML

    go.drugbank.com/bio_entities/BE0005808
    TargetHumans

    Acts as the scaffold of PML-NBs allowing other proteins to shuttle in and out, a process which is regulated by SUMO-mediated modifications and interactions.

    Polypeptides: Protein PMLSynonyms: RING finger protein 71, E3 SUMO-protein ligase PML
  2. Target

    Penicillin-binding protein

    go.drugbank.com/bio_entities/BE0004840
    TargetGram positive and gram negative bacteria

    Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum (PubMed:1103132, PubMed:3531167, PubMed:6450748, PubMed:7030331, PubMed:9614966). … Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

    Polypeptides: Penicillin-binding protein 1A, Penicillin-binding protein 1BSynonyms: Penicillin-binding protein 5, Penicillin-binding protein 4
  3. Target

    cAMP-dependent protein kinase (Protein kinase A)

    go.drugbank.com/bio_entities/BE0010127
    TargetHumans

    Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells … Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells

    Polypeptides: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase catalytic subunit betaSynonyms: PKA C-alpha, PKA C-beta
  4. Target

    Protein ARV

    go.drugbank.com/bio_entities/BE0009193
    TargetPlasmodium falciparum (isolate 3D7)

    Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.

    Polypeptides: Protein ARVSynonyms: Protein ARV1, putative, Conserved Plasmodium membrane protein
  5. Target

    Protein Rev

    go.drugbank.com/bio_entities/BE0010935
    TargetHuman immunodeficiency virus type 1 group M subtype B (isolate HXB2)

    This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.

    Polypeptides: Protein RevSynonyms: Regulator of expression of viral proteins
  6. Target

    IgG heavy chain

    go.drugbank.com/bio_entities/BE0010027
    TargetCarrier

    Constant region of immunoglobulin (Ig) heavy chains. Igs are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound Igs serve as receptors, which upon binding ...

    Synonyms: Heavy chain disease protein, Ig gamma-1 chain C region
  7. Target

    Protein HTATIP2

    go.drugbank.com/bio_entities/BE0002476
    TargetHumans

    Represses translation by preventing reactivation of elongation factor eEF1A (By similarity). May also inhibit nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors (PubMed:15282...

    Polypeptides: Protein HTATIP2Synonyms: HIV-1 TAT-interactive protein 2, 30 kDa HIV-1 TAT-interacting protein
  8. Target

    Protein disulfide-isomerase A3

    go.drugbank.com/bio_entities/BE0008980
    TargetHumans

    Protein disulfide isomerase that catalyzes the formation, isomerization, and reduction or oxidation of disulfide bonds in client proteins and functions as a protein folding chaperone (PubMed:11825568,

    Polypeptides: Protein disulfide-isomerase A3Synonyms: ER protein 57, ER protein 60
  9. Target

    Apolipoproteins

    go.drugbank.com/bio_entities/BE0010065
    CarrierTargetHumans

    Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). … APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids (PubMed:14754908

    Polypeptides: Apolipoprotein C-II, Apolipoprotein C-IIISynonyms: Protein G3a
  10. Target

    Protein Nef

    go.drugbank.com/bio_entities/BE0004237
    TargetHIV-1

    Factor of infectivity and pathogenicity, required for optimal virus replication. Alters numerous pathways of T-lymphocyte function and down-regulates immunity surface molecules in order to evade host defense and increase viral infectivit...

    Polypeptides: Protein NefSynonyms: F-protein