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Valganciclovir
go.drugbank.com/drugs/DB01610ApprovedInvestigationalValganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat cytomegalovirus infections. … As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.
Categories: Cytomegalovirus Nucleoside Analog DNA Polymerase InhibitorProducts: Nat-valganciclovirFlecainide
go.drugbank.com/drugs/DB01195ApprovedInvestigationalWithdrawnFlecainide is a Class I anti-arrhythmic agent like [encainide] and [propafenone]. … [A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics.
Categories: MATE 1 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: N-(2-Piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamideTimolol
go.drugbank.com/drugs/DB00373ApprovedInvestigationalTimolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. … [L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978.
Mixtures: Bimatoprost/Timolol 1A Pharma 0,3 mg/ml + 5 mg/ml - Augentropfen, Lösung, Dorzolamid + Timolol 1A Pharma 20 mg/ml + 5 mg/ml - Augentropfen, LösungProducts: Nu-timolol Tab 5mg, Nu-timolol Tab 20mgSolute carrier family 13 member 4
go.drugbank.com/bio_entities/BE0010199TransporterHumansSodium:sulfate symporter that mediates sulfate reabsorption in the high endothelial venules (HEV)
Synonyms: Na(+)/sulfate cotransporter SUT-1Sertraline
go.drugbank.com/drugs/DB01104ApprovedInvestigationalSertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine].
Categories: Monoamine Oxidase A SubstratesSynonyms: (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamineSalmon calcitonin
go.drugbank.com/drugs/DB00017ApprovedInvestigationalSynthetic peptide, 32 residues long formulated as a nasal spray.
Products: Sandoz-calcitonin NSEzetimibe
go.drugbank.com/drugs/DB00973ApprovedInvestigationalthat NPC1L1 plays an essential role in promoting intestinal cholesterol uptake via an ezetimibe-sensitive pathway. … [A15202] Ezetimibe is used as an adjunctive therapy to a healthy diet to lower cholesterol levels in primary hyperlipidemia, mixed hyperlipidemia, homozygous familial hypercholesterolemia (HoFH), and homozygous
Mixtures: TIAZOMET ® A 40/10 TABLETASProducts: Nra-ezetimibe, Nra-ezetimibe TabletsHydromorphone
go.drugbank.com/drugs/DB00327ApprovedIllicitInvestigationalHydromorphone is a pure opioid,[A176468] a semi-synthetic hydrogenated ketone derivative of [morphine] that has been available clinically since 1920. … Structurally, hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and 8.
Products: HYDROMORPHON-NX 1XTGL 4MG, HYDROMORPHON-NX 1XTGL 8MGDomperidone
go.drugbank.com/drugs/DB01184ApprovedInvestigationalVet approvedA specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Products: Nra-domperidone, Nu-domperidone 10 Mg TabletsCapsaicin
go.drugbank.com/drugs/DB06774ApprovedInvestigationalCapsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. … The most recent capsaicin FDA approval was Qutenza, an 8% capsaicin patch dermal-delivery system, indicated for neuropathic pain associated with post-herpetic neuralgia.
Mixtures: NuDroxiPAK N-500, N-LABS SOLAR MAX Topical AnalgesicCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates