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Perindopril
go.drugbank.com/drugs/DB00790ApprovedInvestigationalIt is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. … Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).
Mixtures: PERINDO/IN RAT T 5/1.25, PERINDO/IN RAT T 5/1.25Synonyms: (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acidGlymidine
go.drugbank.com/drugs/DB01382ApprovedIt is used for the concomitant use with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus. … This increase in intracellular calcium ion concentration induces the secretion of insulin.
Categories: Drugs Used in DiabetesAlclometasone
go.drugbank.com/drugs/DB00240ApprovedAlclometasone is synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent.
Categories: Corticosteroids, Moderately Potent (Group II)Mifamurtide
go.drugbank.com/drugs/DB13615ApprovedInvestigationalMifamurtide is marketed in Europe as Mepact for intravenous infusion. … In the US, it is currently under investigation that holds orphan drug status for the treatment of osteosarcoma [A31746].
Medrogestone
go.drugbank.com/drugs/DB09124ApprovedWithdrawnIt was conceived as an alternative for an orally effective contraceptive option.[A31526] It was developed by Ayerst, approved in Canada in 1969 and its current status is cancelled post-marketing. … [L1118] It was never approved by the FDA.
Tamsulosin
go.drugbank.com/drugs/DB00706ApprovedInvestigational[Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy. … Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.
International brands: Contiflo XLCategories: Drugs Used in Benign Prostatic HypertrophyBesilesomab
go.drugbank.com/drugs/DB13979ApprovedBesilesomab is a mouse monoclonal antibody labelled with the radioactive isotope technetium-99m for determining the location of inflammation/infection in peripheral bone in adults with suspected osteomyelitis … Utilised only as a diagnostic agent, besilesomab is currently approved by the EMEA for marketing and use in various European countries like Italy, France, Germany, Spain, Portugal, Norway, Sweden, the
Tenofovir alafenamide
go.drugbank.com/drugs/DB09299ApprovedInvestigationalTenofovir alafenamide is a novel [tenofovir] prodrug developed in order to improve renal safety when compared to the counterpart [tenofovir disoproxil]. … [A178219] It has been reported to produce a large antiviral efficacy at doses ten times lower than tenofovir disoproxil.
Categories: Antivirals used in combination for the treatment of HIV infectionsRosuvastatin
go.drugbank.com/drugs/DB01098ApprovedInvestigationalfound in clinical studies to result in a 45.8% to 54.6% decreases in LDL cholesterol levels, which is about three-fold more potent than [atorvastatin]'s effects on LDL cholesterol. … the third step in a sequence of metabolic reactions involved in the production of several compounds involved in lipid metabolism and transport including cholesterol, low-density lipoprotein (LDL) (sometimes
Categories: Drugs Used in DiabetesSynonyms: (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acidCentella asiatica
go.drugbank.com/drugs/DB14256ApprovedCentella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mixtures: Oil, Oil