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Iproclozide
go.drugbank.com/drugs/DB09247ApprovedWithdrawnAlthough it was employed as an antidepressant for a time, the fact that the agent is capable of causing fulminant hepatitis and that its use has been documented as the cause for at least three reported … Iproclozide is an irreversible and selective hydrazine class based monoamine oxidase inhibitor (MAOI).
Caroxazone
go.drugbank.com/drugs/DB09254ApprovedWithdrawnCaroxazone is an antidepressant that has been withdrawn from the market. It is a reversible monoamine oxidase inhibitor (MAOI) of both A and B monoamine oxidase subtypes. … However, it presents a five-fold preference for the MAO-B subtype.
Categories: Heterocyclic Compounds, 1-RingBemiparin
go.drugbank.com/drugs/DB09258ApprovedInvestigationalWithdrawnLike semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class [A7866]. … Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH).
Products: HIBOR 10000 IU/0,4 ML SC KULLANIMA HAZIR ENJEKTÖR, 2 ADET, HIBOR 5000 IU/0,2 ML SC KULLANIMA HAZIR ENJEKTÖR, 2 ADETIdarucizumab
go.drugbank.com/drugs/DB09264ApprovedIdarucizumab is a humanized monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype molecule that binds to and inactivates the oral anticoagulant dabigatran, thereby reversing its … As a direct acting oral anticoagulant (DOAC), one of the risks associated with the use of dabigatran includes bleeding, espeically when given to patients at increased risk (elderly, chronic kidney disease
Products: PRAXBIND®, PRAXBİND 50 MG/ML ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 2 ADETDoxofylline
go.drugbank.com/drugs/DB09273InvestigationalDecreased affinity for adenosine receptors may account for the better safety profile of doxofylline compared to theophylline [L1169]. … Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7.
Mixtures: MUCOFIX 600/200 MG EFERVESAN, 5 ADET, MUCOFIX 1200/400 MG EFERVESAN TABLET, 5 ADETCategories: Cytochrome P-450 Substrates, Adrenergic beta-2 Receptor AgonistsImolamine
go.drugbank.com/drugs/DB09284InvestigationalIt is developed under the brand name Coremax by Novartis consumer health SA. … Imolamine is a compound with a molecular weight of 260.33 g/mol with the formula diethyl[2-{5-imino-3-phenyl-4,5-dihydro-1,2,3-oxadiazol,-4-yl)ethyl]amine.
Synonyms: 3-Phenyl-4-diethylaminoethyl-5-imino-1,2,4-oxadiazolCategories: Heterocyclic Compounds, 1-RingPropacetamol
go.drugbank.com/drugs/DB09288InvestigationalPropacetamol is a parenteral formulation of paracetamol and thus, it is a prodrug that is completely hydrolyzed to paracetamol. … [A32051] It is a derivative of [acetaminophen], or paracetamol, with the molecular formula glycine, N, N-diethyl-,4-(acetylamino)phenyl ester.
Categories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesTalniflumate
go.drugbank.com/drugs/DB09295InvestigationalIn addition, it is used in inflammatory conditions such as rheumatoid arthritis. … Talniflumate, is an anti-inflammatory molecule studied and used as a mucin regulator in the treatment of cystic fibrosis, chronic obstructive pulmonary disease (COPD) and asthma [L1400].
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingKitasamycin
go.drugbank.com/drugs/DB09309ExperimentalKitasamycin is a macrolide antibiotic derived from <em>Streptomyces kitasatoensis</em>.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsSynthetic Conjugated Estrogens, A
go.drugbank.com/drugs/DB09317ApprovedAvailable as either "Synthetic Conjugated Estrogens, A" containing 9 estrogen derivatives (available as Cenestin) or as "Synthetic Conjugated Estrogens, B" containing 10 estrogen derivatives (available … However, once a woman stops ovulating there is a sharp decline in the production of progesterone and estradiol by the ovaries and a consequent fluctuation in LH and FSH due to a lack of feedback control
Synonyms: Estrogens, Conjugated Synthetic A, Synthetic Conjugated Estrogens, ACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates