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Resveratrol
go.drugbank.com/drugs/DB02709InvestigationalIt exists as cis-(Z) and trans-(E) isomers. The trans- form can undergo isomerisation to the cis- form when heated or exposed to ultraviolet irradiation. In a 2004 issue of Science, Dr. … Sinclair of Harvard University said resveratrol is not an easy molecule to protect from oxidation. It has been claimed that it is readily degraded by exposure to light, heat, and oxygen.
Synonyms: (E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol(E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol, 5-[(E)-2-(4-hydroxyphenyl)vinyl]benzene-1,3-diolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersAspartic acid
go.drugbank.com/drugs/DB00128ApprovedInvestigationalNutraceuticalOne of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
Synonyms: (S)-2-aminosuccinic acid, (S)-2-aminobutanedioic acidMixtures: TRAVASOL PLUS 15% LIBRE DE BISULFITO, TRAVASOL PLUS 15% LIBRE DE BISULFITOQuinethazone
go.drugbank.com/drugs/DB01325ApprovedQuinethazone, marketed as Hydromox, is a thiazide diuretic indicated for hypertension. Patients may experience adverse reactions such as dizziness, dry mouth, nausea, and hypokalemia.
Categories: Heterocyclic Compounds, 2-RingAncestim
go.drugbank.com/drugs/DB09103ApprovedWithdrawnIt is a 166 amino acid protein produced by E. coli with an amino acid sequence that is identical to the natural sequence predicted from human DNA sequence analysis, except for the addition of an N-terminal … It was submitted to the FDA under the status of recommendation for approval with a 10 to 1 votes.
Thimerosal
go.drugbank.com/drugs/DB11590ApprovedThiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent. … Although thimerosal is banned in several countries, it continues to be included as a preservative in some vaccines in the United States and many vaccines in the developing world [L1685].
Categories: Compounds used in a research, industrial, or household settingSynonyms: ethyl(2-mercaptobenzoato-S)mercury sodium salt, [(o-carboxyphenyl)thio]ethylmercury sodium saltTroglitazone
go.drugbank.com/drugs/DB00197ApprovedWithdrawnTroglitazone was withdrawn in 2000 due to risk of hepatotoxicity. It was superseded by pioglitazone and rosiglitazone.
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesTriheptanoin
go.drugbank.com/drugs/DB11677ApprovedInvestigationalTriheptanoin is a source of heptanoate fatty acids, which can be metabolized without the enzymes of long chain fatty acid oxidation.
Plerixafor
go.drugbank.com/drugs/DB06809ApprovedInvestigational[A7118,L45678] As an inhibitor of CXCR4, plerixafor blocks the binding of its ligand, stromal cell-derived factor-1-alpha (SDF-1α). … Since CXCR4 and SDF-1α are involved in the trafficking and homing of CD34+ cells to the marrow compartment, blocking this interaction leads to an increase in CD34+ cell circulating levels.
Products: MOZOBIL®, Enjeksiyonluk Çözelti, 1 ADETAfamitresgene autoleucel
go.drugbank.com/drugs/DB18592ApprovedInvestigationalself-inactivating lentiviral vector (LV) expressing an affinity-enhanced T cell receptor (TCR) specific for the human MAGE-A4. … [L51114] MAGE-A4 is an intracellular cancer-testis antigen that is overexpressed by cancer cells in synovial sarcoma.
Synonyms: AUTOLOGOUS CD4+ AND CD8+ T CELLS OBTAINED BY LEUKAPHERESIS, TRANSDUCED WITH AN HIV-DERIVED SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODING AN ENHANCED-AFFINITY T CELL RECEPTOR (TCR) SPECIFIC FOR THE, HUMAN MELANOMA ANTIGEN A4 (MAGE FAMILY MEMBER A4, APrussian blue
go.drugbank.com/drugs/DB06783ApprovedIt is insoluble in water but also tends to form a colloid thus can exist in either colloidal or water-soluble form, and an insoluble form. … It is orally administered for clinical purposes to be used as an antidote for certain kinds of heavy metal poisoning, such as thallium and radioactive isotopes of caesium.
Categories: Compounds used in a research, industrial, or household setting