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Latrepirdine
go.drugbank.com/drugs/DB11725InvestigationalLatrepirdine has been investigated for the treatment of Alzheimer's Disease and Huntington's Disease.
Categories: Heterocyclic Compounds, 2-RingLinerixibat
go.drugbank.com/drugs/DB11729ApprovedInvestigationalLinerixibat is a first-in-class and small-molecule inhibitor of the ileal bile acid transporter (IBAT). … [L56127] PBC is a rare, chronic autoimmune liver disease characterized by the destruction of small bile ducts, leading to cholestasis and the systemic accumulation of bile acids, which are hypothesized
Categories: Cytochrome P-450 CYP3A Inhibitors, Heterocyclic Compounds, 1-RingSynonyms: 3-((((3R,5R)-3-BUTYL-3-ETHYL-7-METHOXY-1,1-DIOXO-5-PHENYL-2,3,4,5-TETRAHYDRO- 1H-1.LAMBDA.6,4-BENZOTHIAZEPIN-8-YL)METHYL)AMINO)PENTANEDIOIC ACID, PENTANEDIOIC ACID, 3-((((3R,5R)-3-BUTYL-3-ETHYL-2,3,4,5-TETRAHYDRO-7-METHOXY-1,1-DIOXIDO-5-PHENYL-1,4-BENZOTHIAZEPIN-8-YL)METHYL)AMINO)-Depatuxizumab mafodotin
go.drugbank.com/drugs/DB11731InvestigationalDepatuxizumab/Denintuzumab mafodotin has been used in trials studying the treatment of Lymphoma, Gliosarcoma, Glioblastoma, Malignant Glioma, Squamous Cell Tumors, and Glioblastoma Multiforme.
Lasmiditan
go.drugbank.com/drugs/DB11732ApprovedInvestigational[A187322,A187319] Selectivity for 5-HT<sub>1F</sub>, a lack of vasoconstrictive activity, and the ability to terminate migraines through neuronal inhibition has resulted in the creation of a new class … [A187316] Triptans abort migraines via action at several serotonin receptors, including 5-HT<sub>1D</sub> and 5-HT<sub>1B</sub> receptors, and activity at the 5-HT<sub>1B</sub> receptor has been specifically
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsProducts: 1 RayvowGalactose
go.drugbank.com/drugs/DB11735ApprovedInvestigationalWithdrawnAs a naturally occurring sugar, it may be found in a number dairy products. Even then, however, it is not generally used as a sweetener considering it is only about 30% as sweet as sucrose. … Galactose has been used in trials studying the treatment and diagnosis of Hepatitis C, Hepatic Cancer, Wilsons Disease, Diabetic Macular Oedema, and Focal Segmental Glomerulosclerosis, among others.
Synonyms: D-Galactose, D(+)-GalactoseRilmenidine
go.drugbank.com/drugs/DB11738ApprovedWithdrawnRilmenidine has been used in trials studying the treatment of Hypertension and Chronic Kidney Disease.
Categories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-2 Receptor AgonistsProducts: Iterium 1 mg - Tabletten, HYPERIUM 1 MG TABLET, 30 ADETRifamycin
go.drugbank.com/drugs/DB11753ApprovedInvestigationalWithdrawnProduct which allowed it to have a status a priority review. … The parent compound of rifamycin was rifamycin B which was originally obtained as a main product in the presence of diethylbarburitic acid.
Mixtures: RIFETEM 250 MG / 3 ML AMPUL, 1 ADET, RİF 250 MG/3 ML IM ENJEKSİYONLUK ÇÖZELTİ (1 AMPUL)Categories: MATE 1 Inhibitors, P-glycoprotein inhibitorsMarizomib
go.drugbank.com/drugs/DB11762InvestigationalMarizomib has been used in trials studying the treatment of Cancer, Melanoma, Lymphoma, Glioblastoma, and Malignant Glioma, among others.
Categories: Heterocyclic Compounds, 1-RingSpebrutinib
go.drugbank.com/drugs/DB11764InvestigationalSpebrutinib has been used in trials studying the treatment of Rheumatoid Arthritis, Lymphoma, Large B-Cell, Diffuse, and Leukemia Lymphocytic Chronic B-Cell.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-(5-FLUORO-2-(4-(2-METHOXYETHOXY)PHENYLAMINO)PYRIMIDIN-4-YLAMINO)PHENYL)ACRYLAMIDE, N-(3-(5-fluoro-2-(4-(2-methoxyethoxy)phenylamino)pyrimidin-4-ylamino)phenyl)acrylamideTalinolol
go.drugbank.com/drugs/DB11770InvestigationalTalinolol has been investigated for the basic science of Gastrointestinal Motility Disorder.
Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates