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Displaying results 1551 - 1560 of 10000 in total
  1. Drug

    Thiosulfuric acid

    go.drugbank.com/drugs/DB09499
    ApprovedInvestigational

    [A252827] Sodium thiosulfate is approved for the treatment of acute cyanide poisoning[L310,L43332,A252832] and it is frequently used in conjunction with sodium nitrite (a salt form of [nitrous acid]). … [A252827] Sodium thiosulfate is rapidly degraded in the stomach; therefore, it is normally administered through other routes, such as intravenous or topical.

    Mixtures: Sodium Polysulthionate, 5-mthf, Sodium polysulthionate, 5-methyltetrahydrofolateCategories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP2B6 Inducers
  2. Drug

    Terlipressin

    go.drugbank.com/drugs/DB02638
    ApprovedInvestigational

    Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor.[A2601] It is a prodrug of [lypressin], or lysine vasopressin. … [L43217] As a potent vasopressor, terlipressin has been investigated in various shock states and conditions with diminished vasomotor tone.

    Products: GLYPRESSIN 1 MG/8,5 ML IV ENJEKSIYONLUK COZELTI ICEREN AMPUL, 5 ADET, GLYPRESSIN 1 MG IV ENJEKSIYONLUK TOZ IÇEREN FLAKON VE ÇÖZÜCÜ AMPUL, 1 ADET
  3. Drug

    Metocurine iodide

    go.drugbank.com/drugs/DB00416
    ApprovedWithdrawn

    It is used as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy Metocurine iodide has a moderate risk of inducing histamine … Metocurine iodide is a benzylisoquinolinium competitive nondepolarizing neuromuscular blocking agent.

    Categories: Heterocyclic Compounds, 2-RingProducts: Metubine Iodide Inj 2mg/ml
  4. Drug

    Ensulizole

    go.drugbank.com/drugs/DB11115
    Approved

    It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths.

    Mixtures: Careone Anti Aging Vitamin Complex 7 in 1, Elements Anti Aging Vitamin Complex 7 In 1Categories: Heterocyclic Compounds, 2-Ring
  5. Drug

    Inotuzumab ozogamicin

    go.drugbank.com/drugs/DB05889
    ApprovedInvestigational

    Inotuzumab ozogamicin is an antibody-drug conjugate consisting of a humanized IgG4 kappa CD22-targeting monoclonal antibody covalently attached to calicheamicin derivative, N-acetyl-gamma-calicheamicin … [A20352] Inotuzumab ozogamicin was first approved by the European Commission in June 2017 for the treatment of relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein substratesProducts: BESPONSA 1 MG IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADET
  6. Drug

    Cefamandole nafate

    go.drugbank.com/drugs/DB14725
    ApprovedWithdrawn

    Categories: Heterocyclic Compounds, 2-RingSynonyms: O-formylcefamandole
  7. Drug

    Meropenem

    go.drugbank.com/drugs/DB00760
    ApprovedInvestigational

    Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. … In August 2017, a combination antibacterial therapy under the market name vabomere was approved for treatment of adult patients with complicated urinary tract infections (cUTI).

    Synonyms: (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acidInternational brands: I-penam
  8. Drug

    Bicisate

    go.drugbank.com/drugs/DB11164
    Approved

    It is used in conjunction with technetium Tc99m as a tracer to measure cerebral blood flow with single-photon emission computed tomography (SPECT). … Bicisate, also known as ethyl cysteinate dimer (ECD), is a N,N'-1,2-ethylene-di-yl-bis-L-cysteinate diethyl ester.

    Products: MON.ECD KIT 1 MG IV ENJEKSİYON İÇİN LİYOZFİLİZE TOZ İÇEREN FLAKON, 2 ADET, Neurolite Kit für ein radioaktives Arzneimittel zur Herstellung einer [99mTc]Technetium–Bicisat- Injektionslösung
  9. Drug

    Trimetrexate

    go.drugbank.com/drugs/DB01157
    Approved

    It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against pneumocystis pneumonia in AIDS patients. Myelosuppression is its dose-limiting toxic effect. … A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase.

    Categories: Heterocyclic Compounds, 2-RingProducts: Neutrexin Pws IV 25mg/vial
  10. Drug

    Codeine

    go.drugbank.com/drugs/DB00318
    ApprovedIllicitInvestigational

    Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory … [A175096] Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.

    Mixtures: Virtussin A/C, Virtussin A/CCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates