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Displaying results 1551 - 1560 of 8010 in total
  1. Drug

    Atoltivimab

    go.drugbank.com/drugs/DB15898
    ApprovedInvestigational

    [A221825, A221830] A recent large-scale study elucidated that both neutralizing and Fc-mediated functions of antibodies were important for therapeutic benefit in animal models of EBOV infection. … INMAZEB™ is produced by Regeneron Pharmaceuticals and was granted FDA approval on October 14, 2020.[L17320]

    Categories: Treatments for Ebola Virus Disease
  2. Drug

    Quazepam

    go.drugbank.com/drugs/DB01589
    ApprovedIllicit

    It was first approved in the US in 1985 and is used as a hypnotic for the treatment of insomnia. … [L44913] It appears to be unique amongst other benzodiazepine derivatives in its relatively high affinity for sleep-promoting α1 subunit-containing GABA<sub>A</sub> receptors and low affinity for other

  3. Drug

    Ropinirole

    go.drugbank.com/drugs/DB00268
    ApprovedInvestigational

    In 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome [A174547]. … It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease.

  4. Drug

    Amantadine

    go.drugbank.com/drugs/DB00915
    ApprovedInvestigational

    An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. … The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.

    International brands: PK-MerzProducts: PK-MERZ, PK-MERZ TABLET 100MG
  5. Drug

    Tyrosine

    go.drugbank.com/drugs/DB00135
    ApprovedInvestigationalNutraceutical

    In animals it is synthesized from [phenylalanine]. It is also the precursor of [epinephrine], thyroid hormones, and melanin.

    Mixtures: KABIVEN EMULSION FOR INFUSION, OLIMEL N7E, emulsion for infusion
  6. Drug

    Tecovirimat

    go.drugbank.com/drugs/DB12020
    ApprovedInvestigational

    [L3626, L3614] Tecovirimat was later approved by Health Canada in December 2021,[L39397] followed by the approval from the European Commission in January 2022. … [A35131,A35143] Tecovirimat was approved by the FDA in July 2018 as the first drug ever approved to treat smallpox.

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  7. Drug

    Leucine

    go.drugbank.com/drugs/DB00149
    ApprovedInvestigationalNutraceutical

    An essential branched-chain amino acid important for hemoglobin formation.

    Mixtures: GLAMIN SOLUTION FOR INFUSION, KABIVEN EMULSION FOR INFUSION
  8. Indication

    Acute Non-Lymphocytic Leukemia

    go.drugbank.com/conditions/DBCOND0038781
    Drugs: Tioguanine
    Synonyms: Acute myeloid leukemia, no International Classification of Diseases for Oncology subtype
  9. Indication

    Cutaneous Melanoma

    go.drugbank.com/conditions/DBCOND0040978
    Drugs: Ipilimumab
    Synonyms: Malignant melanoma, no International Classification of Diseases for Oncology subtype
  10. Indication

    Leukemias

    go.drugbank.com/conditions/DBCOND0035632
    Drugs: Betamethasone · Bupivacaine · Hydrocortisone · Hydrocortisone succinate · Methylprednisolone · Methylprednisolone hemisuccinate +2 more
    Synonyms: Leukemia, no International Classification of Diseases for Oncology subtype