Cutaneous Melanoma (DBCOND0040978)

Identifiers

Synonyms
Melanoma of Skin / Melanoma, Cutaneous / Cutaneous melanoma / Melanoma, Cutaneous Malignant / Malignant melanoma of skin, unspecified / Malignant melanoma of skin stage unspecified / Skin melanoma / Melanoma skin / Malignant melanoma of skin (disorder) / Melanoma of skin (malignant) / Malignant melanoma of skin / Malignant melanoma (morphologic abnormality) / Melanoma / Malignant melanoma (disorder) / Malignant melanoma / Melanoma malignant

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Ipilimumab
A human cytotoxic T-lymphocyte antigen 4 (CTLA-4) blocking antibody used to treat metastatic or unresectable melanoma.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02431676
Survivorship Promotion In Reducing IGF-1 Trialprevention2completed
NCT05169957
Hepatic Ablation of Melanoma Metastases to Enhance Immunotherapy Response, a Phase I Clinical Trial (HAMMER I)treatment1active_not_recruiting
NCT01728051
Expanded Access Study of Melphalan With Delcath CS-PHP System in Patients With Ocular/Cutaneous Melanoma Mets to LiverNot AvailableNot Availableno_longer_available
NCT06008977
Exercise to Boost Response to Checkpoint Blockade ImmunotherapyNo drug interventionsotherNot Availablerecruiting
NCT05970497
A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid TumorsNo drug interventionstreatment1recruiting
NCT05219578
RTX-224 Monotherapy in Patients With Solid TumorsNo drug interventionstreatment1 / 2terminated
NCT04254107
A Safety Study of SEA-TGT (SGN-TGT) in Advanced Cancertreatment1terminated
NCT04020809
Neoadjuvant Atezolizumab in Cutaneous Melanomatreatment1recruiting
NCT05520099
Observational Basket Trial to Collect Tissue to Train and Validate a Live Tumor Diagnostic PlatformNo drug interventionsNot AvailableNot Availablerecruiting
NCT03761017
MGD019 DART® Protein in Unresectable/Metastatic Cancertreatment1active_not_recruiting
NCT02831634
A Feasibility Study to Identify T-cell Responses to Neo-epitopes in Tumor Invaded Lymph Nodes (NeoEpitope)No drug interventionsotherNot Availablecompleted
NCT06319196
Clear Me: Interception Trial to Detect and Clear Molecular Residual Disease in Patients With High-risk Melanomatreatment2recruiting
NCT04792463
Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition SyndromeNo drug interventionsNot AvailableNot Availablerecruiting
NCT05283330
Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing TumorsNo drug interventionstreatment1recruiting
NCT02355574
5-year Study to Track Clinical Application of DecisionDx-Melanoma Gene Expression Profile Assay ResultsNo drug interventionsNot AvailableNot Availableterminated
NCT04253080
Expression of IL4 Induced Gene 1 in Patients With Cutaneous Melanoma: Value in Prognosis and/or in Predictive Response to Immune Checkpoint InhibitorsNo drug interventionsdiagnosticNot Availablerecruiting
NCT05086692
A Beta-only IL-2 ImmunoTherapY Studytreatment1 / 2recruiting
NCT05059444
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy EvaluationNo drug interventionsNot AvailableNot Availablerecruiting
NCT05578872
A Study of ANV419 Alone or in Combination With Approved Treatment in Patients With Cutaneous Melanoma (OMNIA-1).treatment1 / 2recruiting
NCT03611868
A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumorstreatment1 / 2recruiting
NCT03699995
MoleMapper, Visiomed, and Confocal Microscopy in Screening Participants for MelanomascreeningNot Availablerecruiting
NCT01942603
Minimal SN Tumor BurdenNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02355587
Five Year Study to Track Use of DecisionDX-Melanoma Test in Patients With Cutaneous Melanoma and Associated Patient OutcomesNo drug interventionsNot AvailableNot Availableterminated
NCT04702854
Evaluation of Ultrasound Biomicroscopy in the Local Staging of Cutaneous MelanomaNo drug interventionsdiagnosticNot Availablerecruiting
NCT05576077
A Study of TBio-4101 (TIL) and Pembrolizumab in Patients With Advanced Solid Tumorstreatment1recruiting
NCT02288897
PV-10 vs Chemotherapy or Oncolytic Viral Therapy for Treatment of Locally Advanced Cutaneous Melanomatreatment3terminated
NCT05628883
Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanomatreatment1recruiting
NCT03843593
A Study To See Why Patients Agree To or Decline To Have Treatment After SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT05675709
Enhancing Skin Cancer Early Detection and Treatment in Primary CareNo drug interventionsscreeningNot Availableenrolling_by_invitation
NCT03947385
Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusionstreatment1 / 2recruiting
NCT04551352
A Study of RO7293583 in Participants With Unresectable Metastatic Tyrosinase Related Protein 1 (TYRP1)-Positive Melanomastreatment1completed
NCT06223659
EMLA Topical Cream for Treatment of Pain in Patients Receiving Intra-Dermal Technetium 99 Injections for Lymphoscintigraphy for Skin Cancerstreatment2recruiting
NCT02129075
A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanomatreatment2completed
NCT04778449
Quality of Life, Lifestyle, and Psychosocial Factors in Patients With MelanomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT03620019
Denosumab + PD-1 in Subjects With Stage III/ IV Melanomatreatment2completed
NCT03628417
Confirmatory Trial in the Evaluation of Ca Electroporation for the Treatment of Cutaneous MetastasesNo drug interventionssupportive_careNot Availablecompleted
NCT02791334
A Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumorstreatment1active_not_recruiting
NCT04830124
Nemvaleukin Alfa Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Cutaneous or Mucosal Melanoma - ARTISTRY-6treatment2recruiting
NCT04274816
Intradermal Injection of Anti-CTLA-4 in Patients With Stage I/II Melanomatreatment1completed
NCT01729663
Phase II/III Clinical Study CSF470 Plus BCG Plus GM-CSF vs IFN Alpha 2b in Stage IIB, IIC and III Melanoma Patientstreatment2 / 3unknown_status
NCT05571839
A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid TumorsNo drug interventionstreatment1recruiting
NCT02519322
Neoadjuvant and Adjuvant Checkpoint Blockadetreatment2completed
NCT05669430
A Study of GV20-0251 in Patients With Solid Tumor MalignanciesNo drug interventionstreatment1recruiting
NCT03767348
Study of RP1 Monotherapy and RP1 in Combination With Nivolumabtreatment2recruiting
NCT05482074
Olaparib in Unresectable/Metastatic Melanoma With BRCA1/2treatment2withdrawn
NCT01444560
miRNA Machinery in Melanoma, Melanoma Metastases and Benign Melanocytic NaeviNo drug interventionsNot AvailableNot Availablecompleted
NCT04625491
Location of Lower Limb Cutaneous Melanomas as a Prognostic Factor.No drug interventionsNot AvailableNot Availableunknown_status
NCT04706962
TH1902 in Patients With Advanced Solid TumorsNo drug interventionstreatment1recruiting
NCT04042480
A Study of SGN-CD228A in Advanced Solid TumorsNo drug interventionstreatment1terminated
NCT02968680
Sonazoid-Enhanced Ultrasound in Detecting Sentinel Lymph Node in Patients With Cutaneous Melanomadiagnostic1terminated
NCT05544929
A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancerstreatment1recruiting
NCT00679289
Phase II Study of KW2871 Combined With High Dose Interferon-α2b in Patients With Metastatic Melanomatreatment2completed
NCT05253872
The MELAcare Study: A New Method for Surveillance of Melanoma PatientsNo drug interventionshealth_services_researchNot Availablerecruiting
NCT03633110
Safety, Tolerability, Immunogenicity, and Antitumor Activity of GEN-009 Adjuvanted Vaccinetreatment1 / 2completed
NCT05358938
Exercise to Boost Response to Checkpoint Blockade Immunotherapytreatment0active_not_recruiting
NCT03842943
Neoadjuvant Combination Immunotherapy for Stage III Melanomaother2recruiting
NCT04789421
Advanced Non-invasive Diagnostics for Early Cutaneous Tumor Diagnosis, Clinical-therapeutic and Economic ManagementNo drug interventionsdiagnosticNot Availablecompleted