Search
Hydroxyproline
go.drugbank.com/drugs/DB08847ApprovedTherapeutically, hydroxyproline is being studied as an an experimental medicine but is approved in France as a combination topical gel product called Cicactive for small, superficial wounds. … Hydroxyproline is a neutral heterocyclic protein amino acid. It is found in collagen and as such it is common in many gelatin products.
Mixtures: Soo Rye Han Dabityun Jiyun Foundation 21, Soo Rye Han Dabityoon Jiyoon Foundation 23Patent Blue
go.drugbank.com/drugs/DB13967ApprovedInvestigationalPatent blue is aniline dye and it is one of the most common dyes used.[A32573] It is a sodium or calcium salt of diethylammonium hydroxide inner salt. … [L1113] The isomer isosulphan is used in the United States for the same indications than patent blue.[A32574]
Categories: Compounds used in a research, industrial, or household settingMALT Lymphoma
go.drugbank.com/conditions/DBCOND0031062Drugs: ChlorambucilSynonyms: Marginal zone lymphoma, Marginal Zone B-Cell LymphomaTegaserod
go.drugbank.com/drugs/DB01079ApprovedWithdrawn[L5918,F4229] It was, however, voluntarily withdrawn from widespread use in the US market in 2007 after concerns arose over the possibility that tegaserod could potentially cause dangerous cardiovascular … Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).
Categories: Serotonin-4 Receptor Agonist, Serotonin 4 Receptor AgonistsCobimetinib
go.drugbank.com/drugs/DB05239ApprovedInvestigationalIt has been approved in Switzerland and the US, in combination with vemurafenib for the treatment of patients with unresectable or metastatic BRAF V600 mutation-positive melanoma. … Cobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction
Mequinol
go.drugbank.com/drugs/DB09516ApprovedWithdrawnIt is used as an inhibitor for acrylic monomers and acrylonitirles, as a stabilizer for chlorinated hydrocarbons and ethyl cellulose, as an ultraviolet inhibitor, as a chemical intermediate in the manufacture … It is found as an active ingredient in topical drugs used for skin depigmentation indicated for the treatment of solar lentigines.
Categories: Compounds used in a research, industrial, or household settingAmivantamab
go.drugbank.com/drugs/DB16695ApprovedInvestigational[L41469] On December 17, 2025, the U.S. … Amivantamab, also known as JNJ-61186372, is an anti-EGFR-MET bispecific antibody, derived from Chinese hamster ovary cells, approved for the treatment of adult patients with locally advanced or metastatic
Rimonabant
go.drugbank.com/drugs/DB06155ApprovedWithdrawnRimonabant is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. It is an inverse agonist for the cannabinoid receptor CB1. Its main avenue of effect is reduction in appetite. … This decision was made after a U.S. advisory panel recommended the medicine not be approved because it may increase suicidal thinking and depression.
Categories: Cannabinoid Receptor Antagonists, Receptor, Cannabinoid, CB1, antagonists & inhibitorsMoxidectin
go.drugbank.com/drugs/DB11431ApprovedInvestigationalVet approvedIt was first used in cattle followed by an approved use in general animals. It is a semi-synthetic methoxine derivative of nemadectin which is a 16-member pentacyclic lactone of the milbemycin class. … Moxidectin is a potent, broad-spectrum endectocide (antiparasitic that is active against endo- and ecto-parasites) with activity against nematodes, insects, and acari.
Categories: Compounds used in a research, industrial, or household settingNerandomilast
go.drugbank.com/drugs/DB18237ApprovedInvestigational[L54126] Compared to pan-PDE4 inhibitors, selective PDE4B inhibitors are associated with a lower potential for gastrointestinal adverse events.[A274581] On December 19, 2025, the U.S. … Nerandomilast is a phosphodiesterase 4 (PDE4) inhibitor that preferentially inhibits the PDE4B subtype. It has one chiral center and is the R-stereoisomer.