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Corticorelin ovine triflutate
go.drugbank.com/drugs/DB09067ApprovedIt provides a differential diagnosis for Cushing's disease (a pituitary source of ACTH excess) or of ectopic ACTH syndrome (an ectopic source of ACTH excess). … If corticorelin injection results in an increase of plasma ACTH and cortisol, the patient is diagnosed with Cushing's disease.
Masoprocol
go.drugbank.com/drugs/DB00179InvestigationalThe compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils. [PubChem] … A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism.
Categories: Compounds used in a research, industrial, or household settingVotucalis
go.drugbank.com/drugs/DB05032InvestigationalrEV131 is in development for allergic rhinitis, asthma and several inflammatory eye diseases. It is a topically delivered small protein that acts as an anti-inflammatory agent.
Ferric oxide
go.drugbank.com/drugs/DB11576ApprovedInvestigationalIt is one of the three main oxides of iron, the other two being iron(II) oxide (FeO) the rarer form, and iron(II,III) oxide (Fe3O4) which naturally as magnetite.
Mixtures: Au Kah Chuen Fugical, OXIDO DE ZINC - CALAMINA UNGUENTOCategories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of ChemicalsCapivasertib
go.drugbank.com/drugs/DB12218ApprovedInvestigationalTherefore, targeting the PIK3/AKT pathway presents a promising approach for the treatment of breast cancer, leading to the development of capivasertib, a pan-AKT kinase inhibitor. … [A262021] The PIK3/AKT pathway is one of the most commonly activated pathways in breast cancer, mainly through the constitutively active mutation in AKT1, loss of function mutation in PTEN, a negative
Omidenepag isopropyl
go.drugbank.com/drugs/DB15071ApprovedThe use of an EP2 receptor agonist such as omidenepag represents an alternative in these scenarios. Omidenepag IOP-lowering effect is comparable to the one observed with [latanoprost]. … [A253263,A253268] Prostanoid FP receptor agonists (FP agonists), such as [latanoprost], are part of the first-line therapy for ocular hypertension and primary open-angle glaucoma; however, not all patients
Categories: combinations of sulfonamidesLevorphanol
go.drugbank.com/drugs/DB00854ApprovedA narcotic analgesic that may be habit-forming. It is nearly as effective orally as by injection.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeTalquetamab
go.drugbank.com/drugs/DB16678ApprovedInvestigationalIt consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. … Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager.
Synonyms: SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY; BISPECIFIC GAMMA4 HEAVY CHAIN HUMANIZED ANBromhexine
go.drugbank.com/drugs/DB09019ApprovedInvestigationalIt was introduced into the market in 1963, and is widely available as an over-the-counter drug in many countries. … Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion.
Mixtures: BENADRYL WET COUGH, GLICERTOX N FProducts: ROMITOX NF ADULTOS, ROMITOX NF PEDIATRICOTechnetium Tc-99m tetrofosmin
go.drugbank.com/drugs/DB09160ApprovedIt is a lipophilic technetium phosphine dioxo cation that was formulated into a freeze-dried kit which yields an injection. … Technetium Tc-99m tetrofosmin is a drug used in nuclear myocardial perfusion imaging.
Categories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of Chemicals