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Displaying results 1551 - 1560 of 10000 in total
  1. Drug

    Tazobactam

    go.drugbank.com/drugs/DB01606
    ApprovedInvestigational

    It is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections. … and mortality in hospitalized patients.

    Mixtures: PIPERACILINA 4000 MG Y TAZOBACTAM 500 MG, ZERBAXA 1 G/0.5 G INFÜZYONLUK KONSANTRE ÇÖZELTI HAZIRLAMAK IÇIN TOZ IÇEREN FLAKON, 10 FLAKONCategories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Agalsidase beta

    go.drugbank.com/drugs/DB00103
    ApprovedInvestigational

    [A220343] Agalsidase beta was granted FDA approval on 24 April 2003.[L16383] … [A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009.

    Products: ฟาบราไซม์ (5 มก.), FABRAZYME35 MG
  3. Pathway

    Acylcarnitine (4Z,7Z,10S,11E)-10-hydroxy-12-[(1S,2R,5S)-5-hydroxy-3-oxo-2-[(2Z)-pent-2-en-1-yl]cyclopentyl]dodeca-4,7,11-trienoylcarnitine

    smpdb.ca/view/SMP0123478
    Metabolic

    (4Z,7Z,10S,11E)-10-hydroxy-12-[(1S,2R,5S)-5-hydroxy-3-oxo-2-[(2Z)-pent-2-en-1-yl]cyclopentyl]dodeca-4,7,11-trienoylcarnitine is an acylcarnitine. … ,11E)-10-hydroxy-12-[(1S,2R,5S)-5-hydroxy-3-oxo-2-[(2Z)-pent-2-en-1-yl]cyclopentyl]dodeca-4,7,11-trienoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  4. Drug

    Sulfadiazine

    go.drugbank.com/drugs/DB00359
    ApprovedInvestigationalVet approved

    One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.

    Mixtures: TRIMETOVET 24% Injection, Sulfaprim 24% oral solutionCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Substrates
  5. Drug

    Dimetindene

    go.drugbank.com/drugs/DB08801
    ApprovedInvestigational

    Dimetindene (Fenistil) is an antihistamine/anticholinergic used orally and locally as an antipruritic.

    Categories: Antihistamines, Anesthetics, Etc.Products: Dimestil 1 mg/g Gel, DERMOSTİL %0.1 JEL , 30 G
  6. Drug

    Olopatadine

    go.drugbank.com/drugs/DB00768
    Approved

    [A1172] In comparison to other anti-allergenic ophthalmic medications, olopatadine displays a good comfort and tolerability profile since it does not cause perturbation of cell membranes. … It is a structural analog of [doxepin], which has a minimal anti-allergic activity.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: OLOPATADINE HYDROCHLORIDE TABLETS 5 MG MEIJI, PALLADA-NS %6.65 MG/ML NAZAL SPREY, 30 ML
  7. Drug

    Pyrimethamine

    go.drugbank.com/drugs/DB00205
    ApprovedInvestigationalVet approved

    One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.

    Mixtures: SULFADOXINA 500 MG + PIRIMETAMINA 25 MG TABLETASCategories: MATE 2 Inhibitors, Cytochrome P-450 CYP2C8 Inhibitors
  8. Drug

    Perampanel

    go.drugbank.com/drugs/DB08883
    ApprovedInvestigational

    It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures. … The FDA label includes an important black-boxed warning of serious or life-threatening behavioral and psychiatric reactions in patients taking Fycompa™.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersSynonyms: 3-(2-Cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one
  9. Drug

    Hydroxocobalamin

    go.drugbank.com/drugs/DB00200
    ApprovedInvestigational

    It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. … Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency.

    Mixtures: ENJEKSİYONLUK ÇÖZELTİ, 100 AMPUL (50+50), ENJEKSİYONLUK ÇÖZELTİ, 50 AMPUL (25+25)Categories: Heterocyclic Compounds with 4 or More Rings
  10. Drug

    Propiverine

    go.drugbank.com/drugs/DB12278
    Approved

    Overactive bladder syndrome affects millions of elderly individuals in the United States and shows equal prevalence in men and women. … OAB has a negative impact on quality of life and may lead to leakage and inconvenient urinary accidents [L2327], [L2328].

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: MİCTONORM 5 MG KAPLI TABLET, 98 ADET, MİCTONORM 15 MG KAPLI TABLET, 56 ADET