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Triclabendazole
go.drugbank.com/drugs/DB12245ApprovedInvestigationalTriclabendazole, manufactured by Novartis pharmaceuticals, is an antihelminthic drug that was approved by the FDA in February 2019 for the treatment of fascioliasis in humans. … These parasites can infect humans following ingestion of larvae in contaminated water or food.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesBenzylpenicilloyl polylysine
go.drugbank.com/drugs/DB00895ApprovedInvestigationalThe quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for evaluating allergic subjects.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseElbasvir
go.drugbank.com/drugs/DB11574ApprovedElbasvir is an inhibitor of NS5A, a protein essential for viral replication and virion assembly. … genotype 1 and 97% and 100% for genotype 4 after 12 weeks of treatment.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseSodium ferric gluconate complex
go.drugbank.com/drugs/DB09517ApprovedSodium ferric gluconate complex is an iron replacement product for treatment of iron deficiency anemia. … The stable macromolecular complex is negatively charged at alkaline pH with an apparent molecular weight of 289,000 – 440,000 daltons on gel chromatography.
ADH-1
go.drugbank.com/drugs/DB05485InvestigationalAs many tumors become more aggressive, invasive, and malignant, researchers have found that N-cadherin is expressed in greater amounts, making it an important target for developing anti-cancer treatments … ADH-1 may have utility in a wide variety of cancers as N-cadherin is overexpressed in a variety of tumors.
Silicon
go.drugbank.com/drugs/DB12982ApprovedSilicon is under investigation in clinical trial NCT00103246 (Photodynamic Therapy Using Silicon Phthalocyanine 4 in Treating Patients With Actinic Keratosis, Bowen's Disease, Skin Cancer, or Stage I or Stage II Mycosis Fungoides).
Mixtures: BLACKMORES teen multi for GIRLS capsule, Vit-min FormulaAmikacin
go.drugbank.com/drugs/DB00479ApprovedInvestigationalVet approved[F1949] In September 2018, a liposomal inhalation suspension of this drug was approved by the FDA for the treatment of lung disease caused by Mycobacterium avium complex (MAC) bacteria in a small population … M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Amikacin Eberth 250 mg/ml Konzentrat zur Herstellung einer InfusionslösungAbiprubart
go.drugbank.com/drugs/DB19333InvestigationalAbiprubart is being evaluated for its efficacy and safety in participants with Sjögren's Disease in clinical trial NCT06531395
Synonyms: 1-441) [VH (Homo sapiens IGHV1-3*01 (83.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.7] (26-33.51-58.97-103)) (1-114)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (115-212), hinge 1-12 S10>P, Immunoglobulin G4-kappa, anti-[Homo sapiens CD40 (TNFRSF5, tumor necrosis factor receptor (TNFR) superfamily member 5, p50)], humanized monoclonal antibodyAcalabrutinib
go.drugbank.com/drugs/DB11703ApprovedInvestigationalContinued approval for acalabrutinib's currently accepted indication may subsequently be contingent upon ongoing verification and description of clinical benefit in confimatory trials. … It also received Orphan Drug designation, which provides incentives to assist and encourage the development of drugs for rare diseases.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsFluticasone furoate
go.drugbank.com/drugs/DB08906ApprovedInvestigationalFluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications[FDA Label][F4364]. Fluticasone furoate was first approved in 2007[L5965].
Categories: Corticosteroids for inhalation use, Drugs for Obstructive Airway Diseases