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Morphine
go.drugbank.com/drugs/DB00295ApprovedInvestigational[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: MORPHIN HEXAL 100MG RET TAUblituximab
go.drugbank.com/drugs/DB11850ApprovedInvestigational[A244210, A244215,A241045] Ublituximab was initially developed by LFB Group but was licensed to TG Therapeutics in 2012. … [A244195, A244200, A244205] Monoclonal antibodies for B cell depletion rely on their binding affinity and ability to clear bound cells through mechanisms such as antibody-dependent cellular cytotoxicity
Nonacog beta pegol
go.drugbank.com/drugs/DB13933ApprovedInvestigationalIt is produced without animal-derived materials and with an attached 40kDa polyethylene glycol (PEG) molecule for peptide activation by a site-directed glycoPEGylation. … Once activated, the activation molecule with PEG is cleaved to leave the activated factor IX (Factor IXa).
Categories: Compounds used in a research, industrial, or household settingProgesterone
go.drugbank.com/drugs/DB00396ApprovedInvestigationalVet approvedA low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609]. … Progesterone is used in various contraceptive preparations to prevent ovulation and fertilization [T481], [A175612] as well as in other formulations to promote and support pregnancy.
Categories: Hormonal Contraceptives for Systemic UseIdebenone
go.drugbank.com/drugs/DB09081ApprovedInvestigationalDue to its biochemical mode of action, it's thought that idebenone may re-activate viable-but-inactive retinal ganglion cells (RGCs) in LHON patients [L885]. … It is not currently approved for use by either the Food and Drug Administration (USA) or Health Canada.
Categories: Psychostimulants, Agents Used for ADHD and Nootropics, Compounds used in a research, industrial, or household settingMethicillin Resistant Staphylococcus Aureus Infection (MRSA)
go.drugbank.com/conditions/DBCOND0115216Synonyms: Bacterial infection due to unspecified staphylococcus, Infection due to Methicillin resistant Staphylococcus aureusSoft Tissue Sarcoma
go.drugbank.com/conditions/DBCOND0029966Synonyms: Sarcoma, no International Classification of Diseases for Oncology subtypeSquamous Cell Carcinoma In-situ (SCC-is)
go.drugbank.com/conditions/DBCOND0043487Drugs: Aminolevulinic acidSynonyms: Squamous cell carcinoma, no International Classification of Diseases for Oncology subtype, Squamous cell carcinoma in situ, no International Classification of Diseases for Oncology subtypeCasirivimab
go.drugbank.com/drugs/DB15941ApprovedInvestigationalThey are reserved for Emergency Use Authorization (EUA) only.[L23524] In November 2021, the same indication was approved by the EMA. … Casirivimab is a monoclonal antibody combined with [Imdevimab] in Regeneron's antibody cocktail known as REGN-COV2 for the treatment of COVID-19.
Categories: Antiinfectives for Systemic Use, Approved Treatments for COVID-19Vaborbactam
go.drugbank.com/drugs/DB12107ApprovedInvestigationalVaborbactam is added to the therapy to reduce the extent meropenem degradation by inhibiting the serine beta-lactamases expressed by the microorganism of target. … [Label] The treatment aims to resolve infection-related symptoms of cUTI and achieve negative urine culture, when the infections are proven or strongly suspected to be caused by susceptible bacteria.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use