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Afamelanotide
go.drugbank.com/drugs/DB04931Approved[L9092] Despite its relatively recent approval, afamelanotide has been available for use as an orphan drug in both the US and EU since 2008.[L9122,L9125] … [A187202,A187205] Afamelanotide is currently the only approved drug therapy used in the management of erythropoietic protoporphyria, having received approval in the EU in December 2014[L9119] and subsequent
Toripalimab
go.drugbank.com/drugs/DB15043ApprovedInvestigationalThe proliferation of some cancers can be attributed, at least in part, to the suppression of host tumor surveillance.
Influenza A virus A/Victoria/210/2009 X-187 (H3N2) antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB14445ApprovedInvestigationalWithdrawnA seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposin...
Mixtures: FLUZONE High-Dose, FLUZONE High-DoseCretostimogene grenadenorepvec
go.drugbank.com/drugs/DB05148InvestigationalCG0070 is investigated in clinical trials for treating bladder cancer. CG0070 is a solid. CG0070 can potentially destroy cancer cells by two different mechanisms: direct cell killing by the virus and immune-mediated cell killing stimulat...
Amoxapine
go.drugbank.com/drugs/DB00543ApprovedSee toxicity section below for a complete listing of side effects. … In non-depressed individuals, amoxapine does not affect mood or arousal, but may cause sedation. In depressed individuals, amoxapine exerts a positive effect on mood.
Nafarelin
go.drugbank.com/drugs/DB00666ApprovedInvestigationalNafarelin is a potent synthetic agonist of gonadotropin-releasing hormone with 3-(2-naphthyl)-D-alanine substitution at residue 6. Nafarelin has been used in the treatments of central precocious puberty and endometriosis.
Categories: Sex Hormones and InsulinsAcadesine
go.drugbank.com/drugs/DB04944InvestigationalAcadesine has been granted Orphan Drug Designation for B-CLL in the EU.
Prazosin
go.drugbank.com/drugs/DB00457ApprovedInvestigationalPrazosin is a drug used to treat hypertension. Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988. It belongs to the class of drugs known as alpha-1 antagonists. Recently, many studies have evaluated the benefit...
Iclepertin
go.drugbank.com/drugs/DB19058InvestigationalIclepertin is under investigation in clinical trial NCT05211947 (A Study to Test Long-term Safety of Iclepertin in People With Schizophrenia Who Took Part in a Previous CONNEX Study).