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Chloroprocaine
go.drugbank.com/drugs/DB01161ApprovedInvestigational[A252952,L43382] Topical chloroprocaine for ophthalmic use was approved by the FDA in September 2022 for ocular surface anesthesia.[L43387] … Both can be given as intrathecal injections for peripheral and central nerve block, but only the preservative-free formulation can be used for lumbar and caudal epidural blocks.
Ozenoxacin
go.drugbank.com/drugs/DB12924Approveds Xepi (ozenoxacin 1%) as a topically applied cream indicated for the treatment of impetigo caused by *Staphylococccus aureus* or *Streptococcus pyogenes* in adult and pediatric patients 2 months of age
Categories: Antibiotics for Topical UseVenetoclax
go.drugbank.com/drugs/DB11581ApprovedInvestigationalPreviously, this drug was indicated only for patients with 17p gene deletion [F2130]. … A new indication was approved in 2018 for the treatment patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), with or without 17p deletion, who have received at least one
Phenyl salicylate
go.drugbank.com/drugs/DB11071ApprovedIt is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing salicylate (found in [DB00945] ).
Setmelanotide
go.drugbank.com/drugs/DB11700ApprovedInvestigationalSetmelanotide is the first available treatment for patients with pro-opiomelanocortin, proprotein subilisin/kexin type 1, or leptin deficiencies. … [A224449] Other earlier treatments for these patients included gastric bypass surgery.[A224449] Patients taking setmelanotide experienced an average weight loss of 0.6 kg/week.
Quazepam
go.drugbank.com/drugs/DB01589ApprovedIllicit[L44913] It appears to be unique amongst other benzodiazepine derivatives in its relatively high affinity for sleep-promoting α1 subunit-containing GABA<sub>A</sub> receptors and low affinity for other … It was first approved in the US in 1985 and is used as a hypnotic for the treatment of insomnia.
Fluticasone
go.drugbank.com/drugs/DB13867ApprovedInvestigationalWithdrawnThese drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications[F4355,F4358,F4361,F4364][FDA Label].
Categories: Corticosteroids for inhalation use, Drugs for Obstructive Airway DiseasesZiprasidone
go.drugbank.com/drugs/DB00246ApprovedInvestigational[A190525] Luckily, several treatment options for psychotic disorders have been introduced to market since the realization of chlorpromazine's antipsychotic properties in 1952.
Atacicept
go.drugbank.com/drugs/DB06399ApprovedInvestigational[L63797] The US FDA granted accelerated approval to atacicept-vymj on July 7, 2026, to reduce proteinuria in adults with primary IgA nephropathy at risk for disease progression.
Fluspirilene
go.drugbank.com/drugs/DB04842ApprovedWithdrawnA long-acting injectable antipsychotic agent used for chronic schizophrenia.