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Displaying results 1581 - 1590 of 10000 in total
  1. Drug

    Ketorolac

    go.drugbank.com/drugs/DB00465
    ApprovedInvestigational

    [L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511] … Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution.

    Mixtures: Ixoba M, Acunistat-30Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Substrates
  2. Drug

    F-15599

    go.drugbank.com/drugs/DB16936
    Experimental

    Categories: Serotonin 5-HT1 Receptor Agonists, Heterocyclic Compounds, 1-RingSynonyms: (3-chloro-4-fluorophenyl)-(4-fluoro-4-(((5-methylpyrimidin-2-ylmethyl)amino)methyl)piperidin-1-yl)methanone, 4-piperidinemethanamine, 1-(3-chloro-4-fluorobenzoyl)-4-fluoro-n-((5-methyl-2-pyrimidinyl)methyl)-
  3. Drug

    Apinocaltamide

    go.drugbank.com/drugs/DB16241
    Investigational

    Apinocaltamide is under investigation in clinical trial NCT03239691 (A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: Benzeneacetamide, N-[1-[(5-cyano-2-pyridinyl)methyl]-1H-pyrazol-3-yl]-4-[1-(trifluoromethyl)cyclopropyl]-, N-(1-((5-CYANOPYRIDIN-2-YL)METHYL)-1H-PYRAZOL-3-YL)-2-(4-(1-(TRIFLUOROMETHYL)CYCLOPROPYL)-PHENYL)ACETAMIDE
  4. Drug

    Rivastigmine

    go.drugbank.com/drugs/DB00989
    ApprovedInvestigational

    Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase. … Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type.

    Synonyms: m-((S)-1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate, (S)-3-(1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamateCategories: Compounds used in a research, industrial, or household setting
  5. Drug

    Rifamycin

    go.drugbank.com/drugs/DB11753
    ApprovedInvestigationalWithdrawn

    Product which allowed it to have a status a priority review. … The parent compound of rifamycin was rifamycin B which was originally obtained as a main product in the presence of diethylbarburitic acid.

    Mixtures: RIFOCIN 125 MG+5 MG/1,5 ML IM ENJEKSİYON İÇİN SOLÜSYON İÇEREN AMPUL, 100 ADET, RIFOCIN 125 MG+5 MG/1,5 ML IM ENJEKSİYON İÇİN SOLÜSYON İÇEREN AMPUL, 1 ADETCategories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP1A2 Inhibitors
  6. Drug

    Potassium Iodide

    go.drugbank.com/drugs/DB06715
    ApprovedInvestigational

    Saturated solution of Potassium Iodide (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperthyroidism (also known as thyroid storm or thyrotoxic crisis). SSKI can also be used for radi...

    Mixtures: Folika-MG, L THYROX JOD HEXAL 75/150Products: Kaliumiodid SERB 65 mg Tabletten, Kaliumjodid G.L. 65 mg - Tabletten
  7. Drug

    Azimilide

    go.drugbank.com/drugs/DB04957
    Investigational

    Azimilide is an investigational class III anti-arrhythmic drug that blocks fast and slow components of the delayed rectifier cardiac potassium channels. It is not approved for use in any country, but is currently in clinical trials in th...

    Synonyms: 1-((5-(P-CHLOROPHENYL)FURFURYLIDENE)AMINO)-3-(4-(4-METHYL-1-PIPERAZINYL)BUTYL)HYDANTOIN, 2,4-IMIDAZOLIDINEDIONE, 1-(((5-(4-CHLOROPHENYL)-2-FURANYL)METHYLENE)AMINO)-3-(4-(4-METHYL-1-PIPERAZINYL)BUTYL)-Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 Substrates
  8. Drug

    Codeine

    go.drugbank.com/drugs/DB00318
    ApprovedIllicitInvestigational

    Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory … The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities.

    Mixtures: Doladamon P 300 mg/15 mg/10 mg Kaplı Tablet, ACETAMINOFEN 500 MG CODEINA 15 MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Drug

    EHP-102

    go.drugbank.com/drugs/DB16933
    Experimental

    Synonyms: 2-(3,7-Dimethyl-Octa-2, 6-Dienyl)-6-Ethylamino-3-Hydroxy-5-Pentyl-[1,4]Benzoquinone, 2-(3,7-Dimethyl-octa-2, 6-dienyl)¿6-ethylamino-3-hydroxy-5-pentyl-[1,4]benzoquinone
  10. Drug

    Navafenterol

    go.drugbank.com/drugs/DB19195
    Investigational

    Navafenterol is under investigation in clinical trial NCT02971293 (Efficacy, Pharmacokinetics (PK), Safety and Tolerability Study of Inhaled AZD8871).

    Synonyms: -hydroxy-.alpha.-2-thienyl-, trans-4-((3-(5-((((2r)-2-(1,2-dihydro-8-hydroxy-2-oxo-5-quinolinyl)-2-hydroxyethyl)amino)methyl)-1h-benzotriazol-1-yl)propyl)methylamino)cyclohexyl ester, Trans-4-((3-(5-((((2r)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydro-5- quinolinyl)ethyl)amino)methyl)-1h-benzotriazol-1-yl)propyl)(methyl)amino)cyclohexyl hydroxy(di-2-thienyl)acetateCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring