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Displaying results 151 - 160 of 2763 in total
  1. Target

    Protein RecA

    go.drugbank.com/bio_entities/BE0001235
    TargetMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

    Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function.

    Polypeptides: Protein RecA
  2. Target

    Protein cereblon

    go.drugbank.com/bio_entities/BE0004755
    TargetHumans

    Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as MEIS2, ILF2, GLUL … Normal degradation of key regulatory proteins is required for normal limb outgrowth and expression of the fibroblast growth factor FGF8 (PubMed:20223979, PubMed:24328678, PubMed:25043012, PubMed:25108355

    Polypeptides: Protein cereblon
  3. Target

    Lysosomal protective protein

    go.drugbank.com/bio_entities/BE0008657
    EnzymeHumans

    This protein is also a carboxypeptidase and can deamidate tachykinins (PubMed:1694176, PubMed:1756715, PubMed:1907282) … Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability

    Polypeptides: Lysosomal protective proteinSynonyms: Protective protein cathepsin A, Protective protein for beta-galactosidase
  4. Target

    Cytochrome b-c1 complex subunit 7

    go.drugbank.com/bio_entities/BE0003860
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c

    Synonyms: Ubiquinol-cytochrome c reductase complex 14 kDa protein, QP-C
  5. Target

    Eotaxin

    go.drugbank.com/bio_entities/BE0003389
    TargetHumans

    Chemokine that plays a central role in both allergic and non-allergic inflammatory reactions by inducing the migration of different leukocyte types including eosinophils, basophils, macrophages and dendritic cells (PubMed:8597956, PubMed...

    Synonyms: Eosinophil chemotactic protein, C-C motif chemokine 11
  6. Target

    Protein Wiz

    go.drugbank.com/bio_entities/BE0012415
    TargetHumans

    May link EHMT1 and EHMT2 histone methyltransferases to the CTBP corepressor machinery. May be involved in EHMT1-EHMT2 heterodimer formation and stabilization (By similarity)

    Polypeptides: Protein WizSynonyms: Zinc finger protein 803, Widely-interspaced zinc finger-containing protein
  7. Target

    cAMP-dependent protein kinase catalytic subunit beta

    go.drugbank.com/bio_entities/BE0004475
    TargetHumans

    Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs (PubMed:12420224, PubMed:21423175, PubMed:31112131). PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation...

    Polypeptides: cAMP-dependent protein kinase catalytic subunit betaSynonyms: PKA C-beta
  8. Target

    Uncharacterized protein

    go.drugbank.com/bio_entities/BE0004040
    TargetActinoplanes teichomyceticus

    Polypeptides: Uncharacterized proteinSynonyms: Putative uncharacterized protein tcp14, SubName: Putative uncharacterized protein tcp14
  9. Target

    Hexon protein

    go.drugbank.com/bio_entities/BE0003258
    TargetHAdV-2

    Assembled into trimeric units with the help of the chaperone shutoff protein. Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. … Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid.

    Polypeptides: Hexon proteinSynonyms: Protein II
  10. Target

    Penton protein

    go.drugbank.com/bio_entities/BE0001571
    TargetHAdV-2

    Involved in virus secondary attachment to host cell after initial attachment by the fiber protein. … As the virus enters the host cell, penton proteins are shed concomitant with virion acidification in the endosome.

    Polypeptides: Penton proteinSynonyms: Protein III, Penton base protein