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Octisalate

The salicylate portion of the molecule absorbs ultraviolet light to protect skin from the harmful effects of exposure to sunlight, while the ethylhexanol portion functions as an emollient. … Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicylates are weak UVB absorbers and they are generally used in combination with other UV filters.

Dofetilide

and flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter. … Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration (FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation

Polysorbate 80

[L1852] A solubilizing agent acts as a surfactant and increases the solubility of one agent in another. … A substance that would not normally dissolve in a particular solution is able to dissolve with the use of a solubilizing agent.

Sodium phosphate, monobasic, unspecified form

Codeine

The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. … Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory

Vortioxetine

It is classified as a serotonin modulator and stimulator (SMS) as it has a multimodal mechanism of action towards the serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin … Some serotonin receptors seem to play a relatively neutral or insignificant role in the regulation of mood, but others, such as 5-HT1A autoreceptors and 5-HT7 receptors, appear to play an oppositional

Amphetamine

Amphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. … [L5194] During World War II, amphetamine was used to promote wakefulness in the soldiers.

Mirvetuximab soravtansine

tube, or primary peritoneal cancer who have received 1-3 prior systemic treatment regimens. … [A254392,L43967] DM4 is conjugated to the antibody with a drug-to-antibody ratio of 3.5:1.

Delamanid

Spontaneous resistance to delamanid was observed during treatment, where mutation in one of the 5 F420 coenzymes responsible for bioactivation of delamanid contributes to this effect [L1407]. … It is marketed by Otsuka Pharmaceutical Co., Ltd (Tokyo, Japan).

Elranatamab

It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb,[A261060] each of which contributes one heavy chain and one … light chain to drug structure.