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Displaying results 1591 - 1600 of 10000 in total
  1. Drug

    Calcitriol

    go.drugbank.com/drugs/DB00136
    ApprovedInvestigationalNutraceutical

    Administered orally and intravenously, calcitriol is commonly used as a medication in the treatment of secondary hyperparathyroidism and resultant metabolic bone disease, hypocalcemia in patients undergoing … Calcitriol plays a role in plasma calcium regulation in concert with parathyroid hormone (PTH) by enhancing absorption of dietary calcium and phosphate from the gastrointestinal tract, promoting renal

    Synonyms: 1-alpha-25-Dihydroxyvitamin D3Categories: Vitamin D and Analogues, Cytochrome P-450 Substrates
  2. Drug

    Ursodeoxycholic acid

    go.drugbank.com/drugs/DB01586
    ApprovedInvestigational

    Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool. … [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by 7b-epimerization of [chenodeoxycholic acid], which is a primary bile acid.

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 Enzyme InducersProducts: ACIDO URSODESOSSICOLICO SPECIAL PRODUCT'S LINE, Ag-ursodiol
  3. Drug

    Gemtuzumab ozogamicin

    go.drugbank.com/drugs/DB00056
    ApprovedInvestigational

    Marketing approval of gemtuzumab ozogamicin was granted on May 17, 2000 by FDA as a treatment for patients with CD33-positive AML in first relapse who are 60 years of age or older and who are not considered … Gemtuzumab ozogamicin is a recombinant humanized IgG4 kappa antibody which is conjugated with calicheamicin derivative, a cytotoxic antitumor antibiotic isolated from fermentation of Micromonospora echinospora

    Products: MYLOTARG 5 MG IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 FLAKON
  4. Drug

    Codeine

    go.drugbank.com/drugs/DB00318
    ApprovedIllicitInvestigational

    Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory … [A175096] Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.

    Mixtures: Virtussin A/C, Virtussin A/CCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  5. Drug

    Interferon alfa-n1

    go.drugbank.com/drugs/DB00011
    ApprovedWithdrawn

    Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated.

    Categories: Interferon Type I, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: Interferon alpha-n1 (INS)
  6. Drug

    Insulin pork

    go.drugbank.com/drugs/DB00071
    Approved

    Forms a hexameric structure.

    Categories: Drugs Used in Diabetes, Cytochrome P-450 CYP1A2 InducersProducts: Regular Purified Pork Insulin Inj
  7. Indication

    Dry Eyes

    go.drugbank.com/conditions/DBCOND0054254
    Drugs: Acrylic Acid · Carbomer · Carbomer homopolymer type C · Carbopol 974P · Carboxymethylcellulose · Chamomile +12 more
    Synonyms: Vitamin A deficiency with xerophthalmia, Other ocular manifestations of vitamin A deficiency
  8. Drug

    Human varicella-zoster immune globulin

    go.drugbank.com/drugs/DB11621
    ApprovedInvestigational

    Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). … It is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and was approved in 2012 under the name VariZIG to reduce the disease severity in high-risk patients who

    Synonyms: Human herpesvirus 3 immune globulinProducts: Varicella Zoster Immune Globulin Inj
  9. Indication

    Fabry's Disease

    go.drugbank.com/conditions/DBCOND0028300
    Drugs: Agalsidase alfa · Agalsidase beta · Migalastat · Pegunigalsidase alfa
    Synonyms: Alpha-galactosidase A deficiency, Alpha galactosidase A deficiency
  10. Drug

    Obinutuzumab

    go.drugbank.com/drugs/DB08935
    ApprovedInvestigational

    [L54521] It was developed as a Type II anti-CD20 antibody to improve upon first-generation agents like rituximab. … [A274641] As a result, obinutuzumab induces greater antibody-dependent cellular cytotoxicity (ADCC) and a higher degree of direct cell death compared to rituximab.

    Products: GAZYVA 1000 MG IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADET, GAZYVA ® CONCENTRADO PARA SOLUCIÓN PARA INFUSIÓN 1000 MG / VIAL 40 ML