NCT04584216
Effects and Safety of Steam Eye Mask With Acupoints Stimulation No drug interventions other Not Available completed NCT00554879
Acupuncture Treatment of Dry Eye No drug interventions treatment Not Available completed NCT00938951
Evaluate the Ability of Systane Ultra to Improve Subjective Symptoms of Ocular Irritation Post 60 Min. Athletic Performance. No drug interventions supportive_care Not Available completed NCT05476068
Dry Eye Under China's Dynamic COVID-zero Strategy No drug interventions Not Available Not Available completed NCT05777798
Clinical Investigation on the Use of Ophthalmic Solution Based on Sodium Hyaluronate in Treatment of Eye Discomfort No drug interventions Not Available Not Available completed NCT00803387
Dry Eye and Irritation Comparison of Latanoprost With the Preservative Versus Travoprost Without Preservative Not Available Not Available completed NCT01450787
Prevalence of Dry Eyes in Diabetics Compared to Non Diabetics No drug interventions Not Available Not Available terminated NCT01933178
Reproducibility of Anterior Segment Optical Coherence Tomography (AS-OCT) for Imaging Conjunctivochalasis No drug interventions Not Available Not Available completed NCT01991132
Validating the Diagnostic Accuracy of Mediview 2.0 Software as an Image Analysis Tool of Meibomian Glands No drug interventions Not Available Not Available completed NCT02306668
Ocular Surface Dry Eye Microbiome No drug interventions Not Available Not Available unknown_status NCT01918410
Effect of Contact Lens With Alginic Acid in Dry Eye Patients No drug interventions Not Available Not Available completed NCT02123147
Examining the Immunological Process of Autoimmune Patients No drug interventions Not Available Not Available withdrawn NCT01988597
Dry Eye Symptoms and Quality of Life No drug interventions Not Available Not Available completed NCT02153515
Treating Dry Eyes and Corneal Ulcers With Fingerprick Autologous Blood No drug interventions treatment 3 unknown_status NCT01679015
Evaluating Patients With Eye Allergies and Determining if There Are Also Dry Eyes No drug interventions Not Available Not Available completed NCT01933165
Reproducibility of LipiView Ocular Surface Interferometer (LipiView) for Measuring Tear Lipid Layer Thickness No drug interventions Not Available Not Available completed NCT01682460
Pilot Study on the Use of Artificial Tears to Treat Dry Eye in Glaucoma Patients treatment 4 completed NCT06071780
Virgin Coconut Oil Contact Lens as Ocular Rewetting Agent No drug interventions diagnostic Not Available completed NCT01695668
Treatment of Ocular Graft-versus-Host Disease (GVHD) With Topical Loteprednol Etabonate 0.5% prevention Not Available completed NCT05201170
A Phase 3, Multi-Center Study Evaluating PL9643 in Patients with Dry Eye No drug interventions treatment 3 completed NCT06621446
The Beijing Adult Dry Eye Cohort Study No drug interventions Not Available Not Available active_not_recruiting NCT05239494
Dailies Total 1 Sphere Contact Lenses No drug interventions health_services_research Not Available completed NCT05803798
Combined Treatment with Pulsed Light and Photobiomodulation Before Laser Refractive Surgery No drug interventions treatment Not Available active_not_recruiting NCT06607237
Evaluation of Safety and Efficacy of DM-28 for Treatment of Moderate to Severe Ocular Dryness No drug interventions treatment Not Available not_yet_recruiting NCT05902364
Systane® Ultra Preservative Free Lubricant Eye Drops No drug interventions treatment Not Available completed NCT05932238
Systane® Hydration PF and Systane® Hydration Preserved No drug interventions treatment Not Available completed NCT06543303
Evaluation of BTV100 in Subjects With Dry Eye Disease No drug interventions treatment 2 not_yet_recruiting NCT00560703
Treatment of Patients With Blepharitis and Facial Rosacea treatment 2 completed NCT00809003
Assessment of Inflammatory and Functional Changes in the Ocular Surface Associated With Dry Eye Disease No drug interventions Not Available Not Available completed NCT00983203
Acute Comfort and Haze Profile of FID 114657 No drug interventions treatment Not Available completed NCT06324890
PET-CT Imaging Features of Meibomian Glands No drug interventions Not Available Not Available recruiting NCT06482164
The THINK Study Incidence of Neurotrophic Keratopathy) No drug interventions screening Not Available recruiting NCT00673764
The Effect of Systane Ultra Lubricant Eye Drops (FID 112903) on Visual Performance No drug interventions treatment Not Available completed NCT02701764
Can Pregabalin Reduce the Frequency and Severity of Dry Eye Symptoms After Laser-assisted in Situ Keratomileusis? prevention 2 / 3 completed NCT06245421
Evaluation of the Efficacy and Safety of DM934 Versus Théalose on Eye Dryness No drug interventions treatment Not Available active_not_recruiting NCT04129021
Multimodal Ophthalmic Imaging No drug interventions other Not Available unknown_status NCT06158984
Managing Dry Eye in Patients Using Glaucoma Drops No drug interventions treatment Not Available completed NCT05159284
Efficacy and Safety of Topical Hydrocortisone on Signs and Symptoms of Dry Eye Associated to Meibomian Gland Dysfunction treatment 4 recruiting NCT00347984
Product Preference With Systane Compared to Artificial Tears on Frequency of Drop Use No drug interventions treatment Not Available completed NCT06287879
Function and Morphological Characteristics of Meibomian Gland in Patients With Renal Anemia No drug interventions other Not Available recruiting NCT02511379
Clinical Evaluation of Systane® Balance in Dry Eye Subjects No drug interventions treatment Not Available terminated NCT04470479
Oral Pilocarpine in the Treatment of the Dry Eye of Patients With Sjogrens Syndrome treatment 3 completed NCT04120987
Ocular Inflammation in Cataract Patients and Response to Treatment With Xiidra treatment 4 withdrawn NCT03992287
Efficacy and Safety of Hydrolysed Red Ginseng Extract on Dry Eye No drug interventions prevention Not Available unknown_status NCT05632887
The Effect of Eyeliner on Tear Composition, Tear Secretion and Tear Film Stability. No drug interventions Not Available Not Available unknown_status NCT00779987
Autologous Serum Efficacy Study in Patients With Severe Dry Eye treatment 2 completed NCT04527887
Intracanalicular Dexamethasone Insert for the Treatment of Inflammation and Discomfort in Dry Eye Disease (DEcIDED) treatment 4 recruiting NCT05247333
Implementation of a Minor Ailment Service in Community Pharmacy Practice No drug interventions health_services_research Not Available completed NCT06360133
Study of 5% VVN001 Ophthalmic Solution in Dry Eye Disease No drug interventions treatment 3 not_yet_recruiting NCT01160133
To Evaluate the Physical Effects of Systane(R) Lubricant Eye Drops Compared to Refresh Tears(R) Lubricant Eye Drops No drug interventions treatment Not Available completed NCT01959854
Efficacy of Topical 0.2% Xanthan Gum in Patients With Dry Eye No drug interventions treatment Not Available completed NCT05661851
Clinical Evaluation of a Multidose Preservative-free Lubricating Eye Drops Contained in Novelia® Eye Dropper in Non-Contact Lens Wearing Patients treatment 2 completed NCT04127851
Evaluating HA 0.15% Compared With Cyclosporine 0.05%, and Efficacy of Combination Therapy in Dry Eye Disease Patients treatment 4 completed NCT01313351
RPS InflammaDry Detector™ to Determine MMP-9 Levels in Tears No drug interventions Not Available Not Available completed NCT01657253
Efficacy and Safety of PRO-148 Versus Systane®, in Patients With Mild to Moderate Dry Eye treatment 3 completed NCT03846453
A Study to Assess Efficacy and Safety of HL036 in Subjects With Dry Eyes treatment 3 completed NCT00946777
Barrier Function Measurement in Dry Eye Patients After Using Systane Ultra for 30 Days No drug interventions treatment Not Available completed NCT06482177
The COAT Trial: Cequa's Onset of Action Trial treatment 4 completed NCT00702377
Evaluation of SYSTANE Ultra Lubricant Eye Drops No drug interventions treatment Not Available completed NCT04747977
To Assess the Efficacy and Safety of OTX-DED for the Short-term Treatment of Signs and Symptoms of Dry Eye Disease No drug interventions treatment 2 completed NCT01967147
Clinical Outcomes Following Treatment With Systane® Balance in Dry Eye Subjects treatment Not Available completed NCT01614847
Tear Osmolarity Changes After Instilling Isotonic Hyaluronate Artificial Tears No drug interventions treatment 4 completed NCT01057147
Safety and Efficacy Study of Rebamipide 2% Ophthalmic Suspension in Subjects With Dry Eye - Effects on Central Cornea treatment 2 completed NCT06576245
Efficacy of Quantum Molecular Resonance Combined With Intense Pulsed Light in Mixed Dry Eye No drug interventions treatment Not Available completed NCT05248698
Dry Eye Response to Interval Exercise and Mediterranean Diet No drug interventions treatment Not Available unknown_status NCT01076998
Acute Comfort and Blur Profile of a Lubricant Eye Drop Versus a Marketed Eye Ointment No drug interventions treatment Not Available completed NCT05949697
A Prospective Study of the Dry Eye Drink That Evaluates Hydration and Subject's Assessment on Eye Dryness No drug interventions other Not Available not_yet_recruiting NCT00349583
Efficacy of Topical Cyclosporine Versus Tears for Improving Visual Outcomes Following Multifocal IOL Implantation Not Available 4 completed NCT03888183
Effect of Preservative-free Low-dose Hyaluronic Acid-containing Salt Solution on Dry Eye Disease No drug interventions treatment 4 unknown_status NCT04454983
Lipiflow vs iLux Patient Acceptance and Comfort Study No drug interventions other Not Available completed NCT04669561
The Chronology of Lifitegrast Effect on Anterior Surface Rehabilitation (CLEAR) Study treatment 4 completed NCT04911361
The DEPOT Study (Dry Eye Prescription Options for Therapy) treatment 4 completed NCT05931861
Performance and Safety Assessment of T2769 in Contact Lens Wearers With Dry Eye Symptoms. No drug interventions treatment Not Available completed NCT05162261
to Evaluate the Effectiveness and Safety of the Tixel® , VS LipiFlow® in the Treatment of Meibomian Gland Dysfunction No drug interventions treatment Not Available completed NCT04172961
Clinical Efficacy of Two Topical Dry Eye Drops for Central Corneal Stain Clearing Over 90 Days treatment 4 recruiting NCT04785261
Effect of Traditional Chinese Medicine on Basic Tear Secretion and Tear Cytokines in Patients With Dry Eye Disease treatment 2 unknown_status NCT01601028
Hydroxychloroquine Treatment of Dry Eyes in Patients With Primary Sjögren's Syndrome treatment 3 completed NCT01718028
The Effect of SYSTANE® BALANCE on Tear Film Break Up Time in Dry Eye Subjects No drug interventions treatment Not Available completed NCT00243711
A Multi-Center Randomized Study to Evaluate the Efficacy and Safety of an Investigational Lubricant Eye Drop treatment 2 / 3 completed NCT03658811
Intense Pulse Light Treatment With Meibomian Gland Expression of the Upper Eyelids in Dry Eye Disease No drug interventions treatment Not Available completed NCT05601011
Changes of Clinical Characteristics and Tear Film Biomarkers Following FS-LASIK No drug interventions Not Available Not Available recruiting NCT01077011
Acute Comfort and Blur Profile of a Lubricant Eye Drop Versus a Marketed Lubricant Eye Gel No drug interventions treatment Not Available completed NCT02210793
Dry Eye Evaluation After Transepithelial PRK No drug interventions screening Not Available completed NCT04181593
Phase 3 Study of the Safety and Efficacy of OmegaD Softgels in the Treatment of Dry Eye Disease No drug interventions treatment 3 completed NCT04260893
Prospective Study To Assess The Safety And Effectiveness Of Tixel Treatment On Dry Eye Symptoms In Asian Patients No drug interventions treatment Not Available terminated NCT00756093
Acute Comfort and Blurring Profile Evaluation of Marketed Lubricant Eye Drops No drug interventions treatment Not Available completed NCT03079271
An Open Label Comparing the Short Term Efficacy of Lacrisert supportive_care 4 unknown_status NCT04465071
Lubricating Eye Drops After Routine Cataract Surgery supportive_care Not Available completed NCT01161771
Effects of Cataract Extraction Surgery and Limbal Relaxing Incision on Corneal Sensation and Dry Eye No drug interventions Not Available Not Available completed NCT01387971
Using Impression Cytology to Observe the Cytological Changes of Ocular Surface Cells in Various Ocular Surface Disorders No drug interventions Not Available Not Available unknown_status NCT01250171
The Effects of a Single Intravenous Administration of Secukinumab (AIN457) or Canakinumab (ACZ885) in Dry Eye Patients treatment 2 completed NCT04492878
Efficacy and Safety of Ikervis Under Controlled Environmental Conditions Environment treatment 4 completed NCT04541888
Assess the Safety and Efficacy of CsA Ophthalmic Gel in Subjects With Moderate to Severe Dry Eye Disease treatment 3 completed NCT01066988
Evaluation of an Investigational Lubricant Eye Drop on Lipid Layer Thickness No drug interventions treatment Not Available completed NCT04229888
Meibomian Gland Dysfunction Treatment No drug interventions treatment Not Available completed NCT05148507
Optimization of the Ocular Surface Prior to Cataract Surgery Using PROKERA No drug interventions treatment Not Available unknown_status NCT04837807
Digital Device Users Who Are Treated With Systane Hydration PF treatment 4 completed NCT05102409
An Exploratory Clinical Trial to Assess Safety and Tolerability in Subjects With Dry Eye Disease treatment 2 completed NCT05973409
Evaluation of Onefit Scleral Lenses in the Mangement of Dry Eye No drug interventions other Not Available not_yet_recruiting NCT03682809
Evaluation of Systane Complete for the Treatment of Contact Lens Discomfort treatment 4 completed NCT04830956
Evaluation of Comfort in Subjects With Moderate Dry Eye Disease No drug interventions other Not Available completed NCT01294956
A Clinical Evaluation of an Investigational Lubricant Eye Gel (FID 115958D) No drug interventions treatment Not Available completed NCT01129856
Safety and Efficacy Study of EGP-437 (Dexamethasone Phosphate Formulated for Ocular Iontophoresis) to Treat Dry Eye treatment 3 completed NCT00926185
A Study Evaluating the Efficacy of SAR 1118 (0.1%, 1.0%, 5.0%) Ophthalmic Solution in Subjects With Dry Eye Conducted in a Controlled Adverse Environment (CAE) treatment 2 completed NCT04817085
An Evaluation of the Clinical Utility and Safety of the Visant Medical Canalicular Plug No drug interventions treatment Not Available completed NCT05938985
Croatian Version of the Ocular Surface Disease Index Questionnaire (OSDI) No drug interventions Not Available Not Available active_not_recruiting NCT03519815
Clinical Study to Evaluate the Efficacy of Ectoin® Containing Eye Spray for Treatment of Dry Eye Disease No drug interventions treatment Not Available completed NCT04411615
Effect of Re-esterified Triglyceride (rTG) Form Omega-3 Supplements on Dry Eye Following Cataract Surgery No drug interventions treatment Not Available unknown_status NCT03652415
DRy Eye Outcome and Prescription Study No drug interventions Not Available Not Available unknown_status NCT06294015
Efficacy of 20% Autologous Serum Drops in the Treatment of Corneal Epitheliopathy Associated With Antihypertensive Glaucoma Drops. treatment 4 not_yet_recruiting NCT04093037
Analysis of the Diagnostic Performance of LacryDiag, a New Analyzer of the Ocular Surface in the Dry Eye No drug interventions diagnostic Not Available completed NCT02217137
Tear Proteins, Conjunctival Cells and Imaging Eyes in Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients No drug interventions Not Available Not Available completed NCT00622037
Bilateral, Masked Comparison of PEG-400 Based Artificial Tear and Systane for the Treatment of Dry Eye Signs, Symptoms and Visual Quality treatment 4 completed NCT01393132
Comparative Study of Thymosin Beta 4 Eye Drops vs. Vehicle in the Treatment of Severe Dry Eye treatment 2 completed NCT06411132
Study to Evaluate Corneal Neurosensory Abnormalities in Patients With Sjögren's Dry Eye No drug interventions Not Available Not Available recruiting NCT04553432
Dry Eye OmniLenz Application of Omnigen Research Study No drug interventions treatment 4 completed NCT01189032
Late Phase II Confirmatory Study of DE-089 Ophthalmic Solution in Patients With Dry Eye Not Available 2 completed NCT05825352
PMCF Study to Evaluate Performance and Safety of "Ocular Drops Based Upon Carmellose" Used to Relieve Dry Eye Symptoms No drug interventions treatment Not Available completed NCT03265652
IPL and MGX Versus MGX Alone in the Treatment of Dry Eye Disease Secondary to MGD No drug interventions treatment Not Available completed NCT04421300
A Randomized Study of Smile Exercise for Dry Eye treatment Not Available completed NCT05824000
PMCF Study to Evaluate Performance and Safety of "Optrex Double Action Soothing and Lubricating Drops" No drug interventions treatment Not Available completed NCT06513000
Dryness Difference Between Before and After Phacoemulsification No drug interventions Not Available Not Available recruiting NCT05895500
Evaluate the Safety and Efficacy of Calcitonin Gene-Related Peptide (CGRP) Antagonists in Patients With Dry Eye Disease and Asthenopia No drug interventions Not Available Not Available completed NCT05145959
Meibomian Gland Probing in the Sub-Acute Phase of Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis No drug interventions treatment Not Available unknown_status NCT04413370
Dry Eye Screening and Referral System No drug interventions Not Available Not Available unknown_status NCT01178242
Salivary Gland Transplantation in the Treatment of Dry Eye in Patients With Stevens-Johnson Syndrome. No drug interventions treatment Not Available completed NCT03332342
Closed Eye Neutrophils in Dry Eye Disease No drug interventions diagnostic Not Available completed NCT04105842
Refitting Daily Disposable Contact Lens Wearers With Dry Eye Disease With A Different Daily Disposable Lens Type No drug interventions basic_science Not Available completed NCT04714099
Topical Cyclosporine A for the Treatment of Dry Eye: A Randomized Clinical Study treatment 3 completed NCT02970799
Tear Production by Nasal Neurostimulation Compared to Active Control No drug interventions other Not Available completed NCT00802399
Partial Lacrimal Punctual Occlusion No drug interventions treatment Not Available completed NCT04457999
Clinical Outcome of Lipiflow Treatment Prior to Cataract Surgery in Dry Eye Patients No drug interventions treatment Not Available unknown_status NCT05918406
Phase 4 Study Evaluating the Safety of the Nasal Guide With Tyrvaya No drug interventions treatment 4 completed NCT00854906
Keratometric Tear Breakup Time and Fluorescein Tear Breakup Time No drug interventions Not Available Not Available completed NCT06537349
Effects of 3% Diquafosol on Tear Film and Vision-related Quality of Life in Orthokeratology Lens Related Dry Eye treatment Not Available not_yet_recruiting NCT05775536
Detection of Acetylsalicylic Acid and Omega-3 Fatty Acids in Schirmers' Test Strips Using Mass Spectrometry diagnostic 2 completed NCT04730336
Assessing the Impact of Tixel Treatment of Periorbital Wrinkles on Dry Eye Symptoms and Signs No drug interventions treatment Not Available recruiting NCT06013436
AST Combined With 0.05% Cyclosporin Eye Drop Improve Corneal Nerve Density in Patients With SS Dry Eye Not Available Not Available completed NCT01417013
Comparative Efficacy of SYSTANE® ULTRA vs Optive™ in Improving Tear Film Break-up Time No drug interventions treatment Not Available withdrawn NCT05705518
Artificial Tears, Tear Lipids and Tear Film Dynamics treatment 4 completed NCT04297618
The Effect of Xiidra on Comfort and Dryness in Symptomatic Contact Lens Wearers treatment 4 completed NCT04899518
ALY688 Ophthalmic Solution in Subjects With Dry Eye Disease No drug interventions treatment 2 / 3 completed NCT05299619
Tixel Treatment for Dry Eye Symptoms No drug interventions treatment Not Available completed NCT05319041
Herbal Medication to Treat Dry Eye in Peri/ Post-menopausal Women No drug interventions treatment 0 recruiting NCT02420834
Dry Eye Treatment With Artificial Tears No drug interventions treatment Not Available completed NCT06555224
Role of Postoperative Lubrication in Cataract Surgery No drug interventions prevention 4 completed NCT00909324
Efficacy, Tolerability, and Comfort of 0.3% Hypromellose Eyedrops in Patients Undergoing LASIK Surgery treatment 4 completed NCT05528016
Short and Long-term Results of Skin Versus Skin Plus Orbicularis Resection Blepharoplasty No drug interventions prevention Not Available completed NCT04674358
The TRANQUILITY Trial: Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye Disease treatment 2 / 3 completed NCT04159935
Investigating iLux Efficacy in Contact Lens Wearers With Evaporative Dry Eye Disease No drug interventions treatment 4 terminated NCT00695435
Tobramycin Tear Concentrations treatment 1 completed NCT00553735
The Prophylactic Use of Topical Cyclosporine A 0.05% to Prevent Graft Versus Host Disease Related Dry Eye prevention 4 terminated NCT03676335
Assess the Safety and Efficacy of CsA Ophthalmic Gel in Subjects With Dry Eye treatment 2 completed NCT02992535
Effect of Intense Pulse Light (IPL) Treatment on Tear Film Osmolarity No drug interventions treatment 4 unknown_status NCT02128763
Dry Eye Assessment and Management Study treatment 3 completed NCT04320563
Rexon-Eye in Dry Eye No drug interventions treatment Not Available completed NCT02752763
Comparison of Autologous Serum Versus Preservative Free Artificial Tear treatment 4 completed NCT00477763
Oasys vs. Extreme H20 Xtra 59 Not Available 4 completed NCT03879863
The RENEW Trial: A Multi-Center, Randomized, Double-Masked, Parallel-Group, Vehicle-Controlled, Adaptive Phase 3 Clinical Trial to Assess the Safety and Efficacy of Subjects With Dry Eye Disease treatment 3 completed NCT05825586
PMCF Study to Evaluate Performance and Safety of "Distilled Waters-based Eyedrops" Used to Relieve Dry Eye Symptoms No drug interventions treatment Not Available completed NCT00568386
Acute Comfort and Blur of Systane and Optive No drug interventions treatment Not Available completed NCT06119386
Quantum Molecular Resonance Electrotherapy in Severe Dry Eye Disease No drug interventions treatment Not Available completed NCT03334539
A Study to Assess Efficacy of HL036 in Subjects With Dry Eyes treatment 2 completed NCT05692739
Clinical Trial To Determine The Effectiveness And Safety Of Topical Insulin In Dry Eye treatment 4 recruiting NCT00893139
A Study of AL-38583 Ophthalmic Solution 0.05%, 0.010% Versus AL-38583 Vehicle for Dry Eye No drug interventions treatment 2 completed NCT05183022
Total30 Sphere Contact Lenses No drug interventions treatment Not Available completed NCT00348322
Safety/Efficacy of Systane Free vs Refresh Tears treatment Not Available completed NCT05932225
Systane® Complete Preservative Free Lubricant Eye Drops No drug interventions treatment Not Available completed NCT05618730
Safety, Tolerability, Plug Retention and Preliminary Efficacy of Tacrolimus-loaded Punctal Plug in Patients With Moderate to Severe Dry Eye Disease - Cohort B No drug interventions treatment 1 active_not_recruiting NCT00399230
A Comparison of Optive in Patients Previously Using Systane for the Treatment of Dry Eye No drug interventions Not Available 4 completed NCT04213248
Effect of UMSCs Derived Exosomes on Dry Eye in Patients With cGVHD No drug interventions treatment 1 / 2 unknown_status NCT03520348
Safety and Tolerability of the Ophthalmic Gel PRO-167 Versus Corneregel® on Healthy Subjects. treatment 1 completed NCT02975557
Brimonidine Eye Drops for Treatment of Ocular Graft-vs-Host Disease (oGVHD) treatment 1 / 2 terminated NCT06364657
Differences in Corneal Structure and Function in Patients With Sjogrens vs. Non-Sjogrens Dry Eye No drug interventions Not Available Not Available recruiting NCT01227226
Tear Osmolarity Over Time With Artificial Tears diagnostic 4 unknown_status NCT05694026
Management of DE With IPL in Combination With DQS treatment Not Available completed NCT01388426
Moisture Chamber Glasses for Dry Eye in Asian Population No drug interventions treatment Not Available completed NCT03286166
Single Center, Prospective, Randomized, Controlled, Non-significant Risk No drug interventions Not Available Not Available withdrawn NCT06296966
A Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye No drug interventions treatment 2 recruiting NCT02005874
A Study To Investigate The Effects Of A Low Humidity Environment And Visual Tasking On Tear Film Protein Composition No drug interventions Not Available Not Available completed NCT05552820
Electroacupuncture for Mild-to-moderate Dry Eye No drug interventions treatment Not Available recruiting NCT06435182
Study of OT202 in Treating Moderate to Severe Dry Eye No drug interventions treatment 2 completed NCT01240382
Phase III Confirmatory Study of DE-089 Ophthalmic Solution in Patients With Dry Eye Not Available 3 completed NCT05288582
Tear Lipid Layer Thickness Assessments With Perfluorohexyloctane Eye Drops No drug interventions health_services_research Not Available completed NCT03992482
IVIG-eye Drops Treatment for Dry Eye Disease treatment 1 / 2 completed NCT04971031
A Clinical Trial to Assess Subjects With Dry Eye Disease. treatment 2 completed NCT05523531
Prospective Single-center Long-term Follow-up Study of a Series of Cases Previously Included in the QUALVIDON Study No drug interventions Not Available Not Available completed NCT04668131
Study on Curative Effect and Mechanism of Acupuncture on Neuropathic Pain in Dry Eye Disease treatment Not Available completed NCT04704531
Phase II Clinical Study to Evaluate the Efficacy of Multidose Lagricel® Ofteno Ophthalmic Solution as Treatment for Dry Eye Disease. treatment 2 completed NCT03141931
The Effects of Dietary Supplementation With Omega-3 Fatty Acids on Symptoms of Dry Eye No drug interventions treatment Not Available completed NCT01386073
Efficacy of FreshKote and Systane for the Treatment of Dry Eye and Improvement of Osmolarity treatment 4 unknown_status NCT03302273
Corneal Epithelial Stem Cells and Dry Eye Disease No drug interventions treatment Not Available completed NCT02160327
The Role of Cytokines and Mast Cell in the Pathogenesis of SLK, Conjunctivochalasis, and Dry Eye No drug interventions Not Available Not Available unknown_status NCT03925727
Tavilermide Ophthalmic Solution for the Treatment of Dry Eye treatment 3 completed NCT03019627
An 8-week Study to Evaluate Safety and Efficacy of NGF Eye Drops Solution Versus Vehicle in Patients With Dry Eye treatment 2 completed NCT02985827
Symptom Response in Normal and Dry Eye Patients Secondary to Application of a Menthol-Containing Eyedrop (Rohto® Hydra) basic_science 4 completed NCT00607776
Artificial Tears Study in Mild to Moderate Dry Eye Patients treatment 2 completed NCT03116776
Walnut Shell Glasses Moxibustion for Dry Eye Syndrome treatment Not Available unknown_status NCT04702776
Phase IV Clinical Study to Compare the Efficacy of the Ophthalmic Solution Humylub Ofteno® PF With Hyabak® and Lagricel Ofteno® PF as Treatment for Dry Eye. treatment 4 completed NCT03436576
Efficacy of Two Concentrations of Autologous Serum for the Treatment of Severe Dry Eye treatment 3 unknown_status NCT06439394
An Observational Study to Assess Optive MEGA-3 (OM3) on Dry Eye Symptoms and Quality of Life of Adult Participants With Mild to Moderate Dry Eye Disease (DED) No drug interventions Not Available Not Available completed NCT04555694
Comparing Treatment of Dry Eye With Intracanalicular Dexamethasone, Restasis, and/or Lotemax treatment 4 completed NCT01843894
A Phase 1/2, RU-101 Ophthalmic Solution in Patients With Severe Dry Eye No drug interventions treatment 1 / 2 completed NCT01630291
The Effect of Electrical Stimulation on Tear Production No drug interventions treatment Not Available completed NCT00804791
Residence Time Evaluation of Marketed OTC Ophthalmic Products No drug interventions treatment Not Available completed NCT00493662
Cross-Over Evaluation of Two Lubricating Eye Drops Not Available 4 completed NCT05133180
Safety and Efficacy Study on Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease (PROTEGO-1 Study) treatment 3 completed NCT01014780
Tear Film Thickness Measured Using a Novel Technique No drug interventions Not Available Not Available completed NCT02470429
Evaluation of Clinical Outcomes After the Use of SYSTANE® HYDRATION No drug interventions treatment Not Available completed NCT04663529
Correlation Study of Corneal Nerve Changes and Dry Eye in Contact Lens Wearers No drug interventions Not Available Not Available completed NCT00814944
A Dose-Ranging Clinical Study to Assess the Safety and Efficacy of Subconjunctival Injection of Sirolimus in Patients With Dry Eye in the Controlled Adverse Environmental (CAE) Model treatment 2 completed NCT06390644
Effect of Periorbital Massage on Dry Eye Disease No drug interventions diagnostic Not Available active_not_recruiting NCT01589640
Patient Satisfaction and Tear Osmolarity With the Use of Blink Tears, Blink Gel Tears and Systane Balance No drug interventions Not Available Not Available unknown_status NCT00706940
Tear Dynamics After Restasis Treatment in Dry Eye Patients No drug interventions Not Available Not Available completed NCT04803240
Survey: Evaluation of Ocular Surface Disease Symptoms and Patient Satisfaction With Thealoz® Duo After 84 Days of Daily Treatment No drug interventions Not Available Not Available completed NCT06517667
Efficacy and Safety of Different Hyaluronic Acid Tear Substitutes Formulations in Evaporative Dry Eye treatment 2 / 3 completed NCT01254201
The Pathogenesis of Idiopathic Dry Eyes No drug interventions Not Available Not Available completed NCT03368404
A Study to Evaluate the Performance and Safety of CBL-102 Versus Vismed® Multi Eye Drops in the Management of Dry Eye No drug interventions treatment Not Available completed NCT02219204
Randomised Research Comparing Acupuncture, Herbal Treatment and Artificial Tear Eye Drops in Dry Eye No drug interventions treatment Not Available completed NCT01051804
Evaluation of the Repeated Usage of Systane Ultra Eyedrop No drug interventions treatment 4 completed NCT05320172
Platelet Rich Plasma in Corneal Surface Diseases treatment 3 not_yet_recruiting NCT04498468
Safety and Efficacy of Dexamethasone Ophthalmic Insert (Dextenza®) in the Management of Clinically Significant Dry Eye treatment 4 terminated NCT03840668
Healthy Living Through Personalized Monitoring of Eyelid Care No drug interventions other Not Available recruiting NCT06159569
Performance and Tolerability of the Medical Device LACRIACT No drug interventions treatment Not Available completed NCT00724412
Evaluate Artificial Tear Efficacy in Moderate to Severe Dry Eye No drug interventions treatment 4 completed NCT03787212
MiBo ThermoFlo Lid Temperature Evaluation No drug interventions treatment Not Available terminated NCT05056012
Penn SICCA Follow-up Study No drug interventions Not Available Not Available not_yet_recruiting NCT01482312
Effect of Contact Lenses on Tear Osmolarity in a Controlled Low Humidity Chamber No drug interventions treatment Not Available completed NCT05383612
To Evaluate the Efficacy of Diquafosol Sodium in the Treatment of MGD in Different Treatment Pattern treatment Not Available recruiting NCT05990712
The Effect of a Pre-cataract Surgical Ocular Hygiene Regime on Microbial Load, Tear Osmolarity, Dry Eye, and Inflammatory Markers prevention 4 not_yet_recruiting NCT04877210
Effects of Topical Insulin on Levels of Tear Inflammatory Mediators treatment 1 unknown_status NCT02951910
A Study of the Effect of Zinc-Hyaluronate on Ocular Surface Sensations in Patients With Dry Eye No drug interventions treatment 4 completed NCT06351410
Assessment of Tear Production, Corneal Staining, and Comfort Level Wearing Different Types of Contact Lenses No drug interventions diagnostic Not Available not_yet_recruiting NCT01438281
Study to Evaluate the Ocular Tolerance of SYL1001 in Healthy Volunteers treatment 1 completed NCT05906381
Dry Eye Symptom Mitigation by Oral Intake of Probiotics No drug interventions treatment Not Available recruiting NCT03097614
Dry Eye Symptom Relief Assessment With Use of TrueTear in a Controlled Adverse Environment No drug interventions treatment Not Available completed NCT05911555
Mucin Levels in Dry Eye and Normal Populations No drug interventions Not Available Not Available completed NCT04889950
Clinical Study to Evaluate the Safety and Effectiveness of The Tixel Fractional System in the Treatment of Meibomian Gland Disfunction No drug interventions treatment Not Available completed NCT03645850
Evaluation of Efficacy and Safety of Vismed Gel Multi 0.3% Versus Vismed Multi 0.18% on Treatment of Ocular Dryness No drug interventions treatment Not Available unknown_status NCT04838223
Neurosensory Abnormalities in SymptomAtic Ocular Surface Patients (NASA) No drug interventions Not Available Not Available enrolling_by_invitation NCT02051023
Efficacy and Safety of Fluorometholone (FML) in Dry Eye Disease (Keratoconjunctivitis Sicca) treatment 3 completed NCT04835623
CEQUA for Sjogren's Syndrome Dry Eye treatment 4 completed NCT05045508
Investigator Initiated Study to Assess the Efficacy of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease Following Photorefractive Keratectomy (PRK) treatment 3 unknown_status NCT05011708
I-DROP MGD Symptomatic Relief and Tear Film Stability No drug interventions treatment Not Available completed NCT04556838
Study of VVN001 Ophthalmic Solution in Dry Eye Disease No drug interventions treatment 2 completed NCT03204903
Laser Acupuncture for Dry Eye No drug interventions treatment Not Available unknown_status NCT02193490
DNase Treatment for Dry Eyes treatment 1 / 2 terminated NCT05062564
Efficacy of LipiFlow in Patients Affected by Meibomian Gland Dysfunction in Reducing Post-cataract Surgery Dry Eye No drug interventions treatment Not Available completed NCT02102464
Treatment of Meibomian Gland Dysfunction and Dry Eye in Contact Lens Wearers No drug interventions treatment Not Available completed NCT01165164
An Evaluation of the Nighttime Retention of Effect of an Investigational Lubricant Eye Drop (FID 115958D) No drug interventions treatment Not Available completed NCT02199964
The Effects of Cyclosporin A in a Low Humidity Environment, on the Ocular Surface prevention Not Available terminated NCT01023464
Tear Film Break-Up Time Evaluation of FID 114657 No drug interventions treatment Not Available completed NCT03848221
Direct Application of Systane Complete to Contact Lenses treatment 4 completed NCT01105221
Acupuncture for Dry Eye treatment 3 completed NCT04196621
Clinical Evaluation of Reproducibility of Keratometric Measurements and Influencing Factors in Cataract Patients No drug interventions diagnostic Not Available completed NCT05079321
Ocular Effects of Scleral Lens Wear on Dry Eye Patients No drug interventions treatment Not Available completed NCT05109702
A Study to Assess the Efficacy and Safety of Tanfanercept (HL036) Ophthalmic Solution in Participants With Dry Eye treatment 3 completed NCT02975102
A Study to Evaluate the Performance and Safety of CBL-101 Versus Vismed® Multi Eye Drops in the Management of Dry Eye No drug interventions treatment Not Available completed NCT01101984
Study of DE-089 Ophthalmic Solution in Patients With Dry Eye treatment Not Available completed NCT02925884
Effects of Gunnar Computer Glasses on Viewing Comfort and Performance No drug interventions Not Available Not Available terminated NCT02952079
Comparison of BlephEx to MiBoflo as Treatment Options for Blepharitis No drug interventions treatment Not Available completed NCT03515187
Study on Prevention and Treatment of Dry Eye in Patients Using Glaucoma Drops treatment 3 unknown_status NCT06329687
A Study Evaluating the Safety of the Nasal Pump treatment 4 terminated NCT04952987
Dry Eye Management With 3% Diquafosol Before and After Cataract Surgery Not Available Not Available unknown_status NCT01741987
Osmoprotective Containing Lubricants in Dysfunctional Tear Syndrome and Post Refractive Surgery Patients No drug interventions treatment Not Available completed NCT05027087
The Effect of a Novel Blueberry Supplement on Dry Eye Disease No drug interventions treatment 3 completed NCT01118754
Study Assessing Safety and Efficacy of DE-101 Ophthalmic Suspension in Dry Eye Patients No drug interventions treatment 1 / 2 completed NCT05720754
Temperature on Evaporative Dry Eye treatment Not Available not_yet_recruiting NCT06176651
Evaluation of Miebo (Perfluorohexyloctane) Eyedrops in Habitual Contact Lens Wearers treatment 4 completed NCT04425551
Effect of Micropulse Laser on Dry Eye Disease Due to Meibomian Gland Dysfunction No drug interventions treatment Not Available unknown_status NCT03640351
Clinical Effects of Diquas-S for Patients With Dry Eye After Cataract Surgery treatment Not Available completed NCT03652051
A Multicenter Study Evaluating AZR-MD-001 in Patients With Meibomian Gland Dysfunction and Evaporative Dry Eye Disease (DED) No drug interventions treatment 2 completed NCT05748951
Evaluating a Device for Blocking the Tear Duct No drug interventions treatment Not Available completed NCT01384851
Efficacy of the Chronic Application of Tear Formulations treatment Not Available unknown_status NCT03211351
Effects of Two Tear Substitutes in Patients With Dry Eye Syndrome treatment Not Available completed NCT06309953
A Study to Evaluate Early Treatment Outcomes With Miebo™ in Subjects With Dry Eye Disease treatment 4 completed NCT06219577
Subjective and Objective Performance of Systane Complete Multi-Dose PF Versus Walgreen's Lubricant Balance treatment 4 completed NCT06544447
Transcutaneous Auricular Vagus Nerve Stimulation in Dry Eye Disease With Meibomian Gland Dysfunction treatment 1 / 2 recruiting NCT00522847
Biochemical Factors for a Dry Eyed Population No drug interventions Not Available Not Available completed NCT04535947
Study to Evaluate the Efficacy of SDP-4 in Subjects With Dry Eye Disease (DED) (SDP-4-CS202) No drug interventions treatment 2 completed NCT01387347
Safety and Efficacy of Thymosin Beta 4 Ophthalmic Solution in Patients With Dry Eye treatment 2 completed NCT03414645
Topical Fibrinogen-Depleted Human Platelet Lysate in Patients With Dry Eye Secondary to Graft vs. Host Disease treatment 1 / 2 completed NCT03194698
Efficacy of IPL Treatment of Dry Eye and Ocular Rosacea No drug interventions treatment Not Available completed NCT00809198
Kynex Versus Refresh Plus Study in Subject With Dry Eye No drug interventions treatment 4 completed NCT01368198
Evaluation of Extended Tear Film Break Up Time (TFBUT) With an Ocular Emulsion No drug interventions basic_science Not Available completed NCT03012698
Pilot Study for Testing Safety of Repetitive Magnetic Stimulation for Treatment of Dry Eye No drug interventions treatment Not Available completed NCT03417505
Tangible Hydra-PEG: A Promising Solution for Scleral Lens Wearers With Dry Eye No drug interventions supportive_care Not Available completed NCT06271005
Neurological Dry Eye Study Stimulating Both Lacrimal and Vagus Nerves No drug interventions treatment Not Available not_yet_recruiting NCT01016405
Prospective Health Assessment of Cataract Patients' Ocular Surface No drug interventions Not Available Not Available completed NCT02148497
Multi-Colored Placido Disk Viability No drug interventions diagnostic Not Available completed NCT03693183
Efficacy Study of Ketorolac and HPMC to Treat Dry Eye treatment 2 withdrawn NCT00399061
Efficacy of Optive Versus Systane Concomitant With Restasis (Cyclosporine A) for the Treatment of Dry Eye Symptoms treatment 4 completed NCT05306561
Evaluating Impact of Systane iLux on Dryness Symptoms and Wearing Time in Contact Lens Users No drug interventions treatment Not Available recruiting NCT05823961
PMCF Study to Evaluate Performance and Safety of "CLHA-based Eyedrops" Used to Improve Lacrimal Abnormalities No drug interventions treatment Not Available completed NCT06525961
iTear Single-center, Open-label, Single-arm Study No drug interventions treatment 4 not_yet_recruiting NCT05923528
Comparison of Non-pharmaceutical Treatments for Evaporative Dry Eye No drug interventions treatment Not Available not_yet_recruiting NCT04163328
Effects of Supplementation With PUFAs and Antioxidants for Contact Lens Discomfort No drug interventions treatment 4 terminated NCT04510428
OSIG-eye Drops Treatment for Dry Eye Disease treatment 2 withdrawn NCT03878628
Treatment With Allogeneic Adipose-derived Mesenchymal Stem Cells in Patients With Aqueous Deficient Dry Eye Disease No drug interventions treatment 0 completed NCT05467293
Phase 2, Multi-center, Randomized, Double- Masked and Placebo-Controlled Study of YP-P10 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye (ICECAP 1) No drug interventions treatment 2 completed NCT03945071
The Effect of Punctal Plugs on Ocular Surface After Povidone-Iodine Preparation of Intravitreal Injection No drug interventions prevention Not Available completed NCT05191771
Evaluation of Neovis® Total Multi Versus Systane® Balance on Ocular Dryness Associated With Meibomian Gland Dysfunction No drug interventions treatment Not Available unknown_status NCT03006978
Pilot Study of the TearCare System No drug interventions treatment Not Available unknown_status NCT01748578
Phase 1 Study for Safety and Tolerability of EBI-005 Topically Administered to Eyes of Healthy Adult Subjects treatment 1 completed NCT03061578
Evaluation of Dry Eye by Tear Film Imager in a Low Humidity Environmental Exposure Chamber (TFI-LH16) No drug interventions Not Available Not Available completed NCT05965778
Comparison of the Performance and Safety of T2769 Versus Vismed® Multi in the Treatment of Moderate to Severe Dry Eye Syndrome No drug interventions treatment Not Available recruiting NCT03865888
Comparing Effect of Topical Tacrolimus 0.03% Versus Cyclosporine 0.05% in Dry Eyes of Secondary Sjogren Syndrome treatment 3 completed NCT01257607
Safety and Efficacy Study of MIM-D3 Ophthalmic Solution for the Treatment of Dry Eye treatment 2 completed NCT04092907
A Study Evaluating the Efficacy and Safety on Moderate to Severe Dry Eye No drug interventions treatment 2 completed NCT01521507
Randomized Controlled Trial of Long-term Treatment Effectiveness for Meibomian Gland Dysfunction (MGD) and Dry Eye No drug interventions treatment Not Available completed NCT06354309
The Impact of Immersive Virtual Reality Training on Adult: Motion Sickness, and Ocular Surface: A Pilot Study No drug interventions other Not Available completed NCT01660256
Confirmatory Study of OPC-12759 Ophthalmic Solution treatment 3 completed NCT01267656
Study to Evaluate a Contact Lens Lubricating and Rewetting Drop No drug interventions screening Not Available completed NCT04648085
Effect of Trigeminal Nerve Stimulation on Corneal Nerves and Chronic Ocular Pain No drug interventions supportive_care Not Available completed NCT05600985
Clinical Characteristics of Patients Developing Chronic Dry Eye After Refractive Surgery No drug interventions Not Available Not Available recruiting NCT06379685
Study to Evaluate the Safety and Tolerability of PRO-190 Ophthalmic Solution Compared to Systane Ultra® on the Ocular Surface. treatment 1 not_yet_recruiting NCT03408015
Effects of Xiidra on Closed Eye Tear Film Leukocytes in Dry Eye Disease basic_science 4 withdrawn NCT03617315
Crosslinked Hyaluronic Acid With Liposomes and Crocin in Dry Eye No drug interventions treatment Not Available completed NCT03768115
Autologous Plasma Treatment for Severe Dry Eye Patients treatment 0 withdrawn NCT05754437
Efficacy of Low-Level Light Therapy in Reducing Dry Eye in Patients Undergoing Cataract Surgery No drug interventions prevention Not Available recruiting NCT01030237
An Evaluation of the Safety and Efficacy of FID 114657 No drug interventions treatment Not Available completed NCT05304637
Usability, Immediate, and 30 Day Effect of External Neuromodulation With iTEAR100 Generation 2 in Dry Eye Patients No drug interventions treatment 4 unknown_status NCT06269237
Point of Care Test of LTA Level in Tear Fluid, Measured With a POCT Test, in DE Patients Following IPL Treatment No drug interventions treatment Not Available not_yet_recruiting NCT01476332
Safety, Tolerability and Pharmacokinetics of 0.5% and 2.5% Cis-UCA Eye Drops in Adult Healthy Volunteers (Phase I) No drug interventions treatment 1 completed NCT05131152
Microvascular and Inflammatory Responses of 0.05 Cyclosporine Eye Drop (II) in Treatment of Dry Eye treatment Not Available unknown_status NCT04795752
Prospective, Randomized, Masked, Controlled Trial To Evaluate The Safety And Effectiveness Of The TearCare® System In The Treatment Of The Signs And Symptoms Of Dry Eye Disease (SAHARA) treatment Not Available unknown_status NCT02468700
OTX-14-006: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Dry Eye treatment 2 completed NCT04115800
Liposomal Sirolimus in Dry Eye Disease treatment 0 completed NCT00439400
A Study of ALTY-0501 for the Treatment of Dry Eye Administered 4 Times a Day for a 56 Day Period Not Available 2 completed NCT02235259
Efficacy and Safety of XG-104 for the Treatment of Dry Eye No drug interventions treatment 2 completed NCT00673959
Acute Comfort of Lubricant Eye Drop FID 111421 No drug interventions treatment Not Available completed NCT06443775
An Observational Study to Assess Next Generation Emulsion Preservative Free Eye Drops (NGE-UD) on Dry Eye Symptoms and Quality of Life of Adult Participants With Mild to Moderate Dry Eye Disease (DED) Not Available Not Available recruiting NCT00704275
Comparison of Efficacy, Safety and Anti-Inflammatory Effect Between Topical 0.05%Cyclosporine A Emulsion and REFRESH® in Patients With Moderate to Severe Dry Eyes treatment 4 unknown_status NCT04109170
Dry Eye Evaluation System Based on Bioinformatics No drug interventions Not Available Not Available unknown_status NCT02776670
Clinical Outcomes Following Treatment With SYSTANE® BALANCE No drug interventions treatment Not Available completed NCT03916042
A Multi-Center, Randomized, Double-Masked, Parallel-Group, Vehicle-Controlled, Clinical Trial of Reproxalap to Assess the Safety and Efficacy in Subjects With Dry Eye Disease treatment 2 completed NCT04418999
Safety and Efficacy of Intracanalicular Dexamethasone Compared to Loteprednol Etabonate in Patients With Keratoconus treatment 0 completed NCT05825599
PMCF Study to Evaluate Performance and Safety of "HPMC-based Eyedrops" Used to Relieve Dry Eye Symptoms No drug interventions treatment Not Available completed NCT05829499
PMCF Study to Evaluate Performance and Safety of "Xanoftal Next" No drug interventions treatment Not Available completed NCT03598699
A Study to Evaluate AXR-159 Ophthalmic Solution in Patients With Dry Eye Disease No drug interventions treatment 2 completed NCT06158906
Validity of Web-Based OSDI-6 Questionnaire in a Chinese Adult Population No drug interventions Not Available Not Available completed NCT03763006
Efficacy and Safety of Ocudox Lid Wipes Compared to Traditional Lid Cleaning No drug interventions prevention 1 completed NCT01629706
Determination of Cell Population in Solution-Induced Corneal Staining (SICS) and Symptomatic Versus Asymptomatic Lens Wearers No drug interventions basic_science Not Available completed NCT04043949
The Influences of Dry Eye Disease on Optical Quality No drug interventions Not Available Not Available completed NCT00739349
NOVA22007 0.05% and 0.1% Cyclosporine Versus Vehicle for the Treatment of Dry Eye treatment 2 completed NCT00743249
Punctal Plug Study to Determine the Safety and Retention Times of Various Lengths of Canalicular Stents in Volunteers No drug interventions screening Not Available completed NCT03691636
Eyelash Prostheses Compared to 5.0% Lifitegrast BID for Dry Eye Disease. No drug interventions treatment Not Available unknown_status NCT05887336
Intra-Nasal Mechanical Stimulation (INMEST) as a Treatment Method for the Relief of Symptoms of Dry Eye No drug interventions treatment Not Available active_not_recruiting NCT01684436
Safety and Efficacy of Punctal Plug Insertion in Patients With Dry Eye No drug interventions treatment 4 completed NCT04633213
A Study Evaluating HBM9036 Efficacy and Safety on Moderate to Severe Dry Eye No drug interventions treatment 3 unknown_status NCT02702518
rhDNase Eye Drops in Patients With Ocular Graft-Vs.-Host Disease treatment 1 / 2 terminated NCT03953118
Azithromycin for Meibomian Gland Disease treatment 4 unknown_status NCT04667819
Wireless Micropump in Dry Eye Patients treatment Not Available unknown_status NCT00471419
Phase II Study of AL-2178 (FID 109980) in the Treatment of Dry Eye treatment 3 completed NCT03857919
TearCare System to Treat Dry Eye Disease No drug interventions treatment Not Available recruiting NCT02365519
LME636 in the Relief of Persistent Ocular Discomfort in Subjects With Severe Dry Eye Disease treatment 2 completed NCT02161341
Ocular Surface Microbiome in Dry Eye Patients No drug interventions Not Available Not Available completed NCT01947517
The Retention Rate Between Brand A and Brand B Punctal Plugs No drug interventions Not Available Not Available completed NCT01833117
Efficacy and Safety Study of FID 119515A No drug interventions treatment Not Available completed NCT00348517
Safety/Efficacy of Systane Free vs Refresh Liquigel No drug interventions treatment Not Available completed NCT04125134
Predicting the Success of Dry Eye Disease Interventions Using Clinical Tests other 4 recruiting NCT06478134
Efficacy and Safety of a Multiple-Action Tear Substitute (TriMix) in Dry Eye Disease treatment 2 / 3 completed NCT03588624
Study of the TearCare System in Dry Eye Disease No drug interventions treatment Not Available unknown_status NCT02980224
Study of the Safety and Efficacy of OmegaD Softgels in the Treatment of Dry Eye Disease No drug interventions treatment 3 completed NCT03769324
Validation of Osmolarity System: Clinical Usability Study No drug interventions Not Available Not Available unknown_status NCT04789824
The Impact of Eyelid Hygiene on Ocular Surface No drug interventions prevention Not Available completed NCT02417116
Tear Osmolarity Clinical Utility in Dry Eye Disease No drug interventions treatment Not Available completed NCT05741216
Evaluation of Comfort of Ocular Lubricants in Symptomatic Contact Lens Wearers No drug interventions treatment Not Available completed NCT03451396
Effect of Lifitegrast on Dry Eye Disease Signs and Symptoms treatment 4 completed NCT04960696
Effect on Ocular Surface Symptoms of Online Education No drug interventions Not Available Not Available completed NCT04063735
Alleviating Effects Against Dry Eye by Oral Intake of Cordyceps Cicadae Mycelia No drug interventions other Not Available completed NCT04131335
Use of Prophylactic Lubricating Drops After Cataract Surgery No drug interventions treatment Not Available unknown_status NCT02234635
Visual Quality Change of Eyes Implanted With Diffractive Multifocal Intraocular Lens After Cataract Surgery No drug interventions treatment Not Available unknown_status NCT00833235
A Natural History Study of Patients With Dry Eye No drug interventions Not Available Not Available completed NCT03889886
Study to Evaluate the Safety and Efficacy of SDP-4 in Subjects With Dry Eye Disease (DED) No drug interventions treatment 2 completed NCT03815539
Correlation of Noninvasive Tear Film Function and the Optical Quality in Mild and Moderate Dry Eye No drug interventions screening Not Available unknown_status NCT02405039
Study of EBI-005 in Dry Eye Disease (DED) Not Available 3 unknown_status NCT03597139
Ocular Tolerability of Voclosporin Ophthalmic Solution Versus Restasis® in Subjects With Dry Eye Disease treatment 2 completed NCT05700422
Nasal Spray Study in Sjogren's Dry Eye Disease treatment 4 completed NCT01611922
Optimization of Assessment and Grading for Lid Wiper Epitheliopathy No drug interventions Not Available Not Available completed NCT01507025
The Effect of Hinge Location on Corneal Sensation and Dry Eye After LASIK: A Systematic Review and Meta-analysis No drug interventions Not Available Not Available completed NCT04313725
Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease No drug interventions treatment Not Available unknown_status NCT03987230
Comfort Associated With The Use Of Eyelid Cleansing Products Available For The Management Of Demodex Folliculorum No drug interventions treatment Not Available completed NCT05062330
The TRANQUILITY 2 Trial: A Phase 3 Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye Disease treatment 3 completed NCT01317030
Tear Evaluation Between Habitual Contact Lens Wearers and Non Contact Lens Wearers No drug interventions Not Available Not Available terminated NCT03460548
REMOGEN® Omega Versus Cationorm® in the Treatment of Patients Suffering From Dry Eye No drug interventions treatment Not Available terminated NCT05322148
Cyclosporine 0.1% / Loteprednol 0.2% Effect on Anterior Segment Normalization treatment 3 completed NCT02380248
Clinical Evaluation of Systane® Gel Drops in Dry Eye Subjects No drug interventions treatment Not Available completed NCT03517748
Evaluation of the Efficacy and Safety of DM05 Versus Optive™ on the Treatment of Moderate to Severe Ocular Dryness No drug interventions treatment Not Available completed NCT00405457
Efficacy and Safety of a New Multi-dose Lubricant Eye Drop Concomitant With Restasis® (Cyclosporine A) for the Treatment of Dry Eye Symptoms treatment 4 completed NCT02257957
Platelet -Rich Plasma (PRP) Injection for the Treatment of Severe Dry Eye treatment 3 completed NCT01791426
A Study to Evaluate the Performance and Safety of Artelac Rebalance® Versus Vismed in the Management of Dry Eye No drug interventions Not Available Not Available withdrawn NCT01335126
Comparison of Tolerability and Clinical Performance of Two Emulsion-type Artificial Tears No drug interventions treatment 3 unknown_status NCT00748865
Acute Comfort and Blur of Systane Ultra and Systane No drug interventions treatment Not Available completed NCT00769665
A 2-week Clinical Comparison of SYSTANE® Ultra to Sensitive Eyes Rewetting Drops in Contact Lens Wearing Patients. No drug interventions Not Available Not Available completed NCT03907865
Clinical Efficacy of Topical Hydrocortisone 0.335% (Softacort®) in Patients With Chronic Dry Eye Disease and Associated Ocular Surface Inflammation No drug interventions treatment 4 completed NCT04111965
Clinical Trial to Compare the Safety and Efficacy of Nanodrop® treatment 1 / 2 completed NCT01086774
Efficacy of Systane Balance to Stabilize the Tear Film in Dry Eye Subjects No drug interventions treatment 4 completed NCT03937882
Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-3 treatment 3 completed NCT04022382
A Study to Evaluate the Safety and Effectiveness Assessments of Restylane-Defyne for Punctual Occlusion No drug interventions device_feasibility Not Available completed NCT01375582
Objective Evaluation of Ocular Surface Lubricants in Two Environments treatment 0 completed NCT06427031
Comparing Efficacy and Safety of TJO-083 in Dry Eye Diseases Patients treatment 3 recruiting NCT04100031
Efficacy of an Ocular Bandage Contact Lens for the Treatment of Dry Eye After Cataract Surgery No drug interventions treatment Not Available completed NCT03208673
Optive Brand For Day And Night Dry Eye Management No drug interventions treatment Not Available completed NCT00469573
Safety and Efficacy of Optive in Contact Lens Wearers With Dry Eyes No drug interventions Not Available 4 completed NCT03265327
Effect of an Oral Supplement Containing Omega-3 and Omega-6 on Dry Eye Symptoms No drug interventions treatment Not Available completed NCT02218827
Topical Steroid Treatment For Dry Eye treatment Not Available unknown_status NCT03418727
Dry Eye Disease Study With Brimonidine treatment 2 completed NCT05573360
Evaluation of Safety and Tolerability of Ocular Lubricants No drug interventions treatment Not Available completed NCT05807360
PMCF Study to Evaluate Performance and Safety of "Hyaluronic Acid (HA)-Based Eyedrops" Used to Relieve Dry Eye Symptoms No drug interventions treatment Not Available completed NCT06120894
Strip Meniscometry in Dry Eye Evaluation No drug interventions Not Available Not Available completed NCT04391894
A Study to Assess the Safety and Efficacy of ECF843 vs Vehicle in Subjects With Dry Eye Disease No drug interventions treatment 2 completed NCT00388791
Comparison of Systane Free vs. Saline in the Treatment of Dry Eye treatment 4 completed NCT06565091
Clinical Investigation for a Multifunction Ophthalmic Measurement Device No drug interventions diagnostic Not Available recruiting NCT02712762
Ocular Surface Disease in Chronic Graft-Versus-Host Disease (GVHD) Patients No drug interventions Not Available Not Available completed NCT06017362
Clinical Trial To Determine The Efficacy And Safety Of Insulin Eye Drops In Dry Eye In Patients With Topical Hypotensors treatment 4 recruiting NCT03566680
Treating Contact Lens Discomfort With Orthokeratology No drug interventions treatment Not Available completed NCT03866629
The Effect Of Lifitegrast On Refractive Accuracy And Symptoms In Dry Eye Patients Undergoing Cataract Surgery Not Available Not Available completed NCT04515329
Tear Film Markers in Dry Eye Syndrome treatment 4 withdrawn NCT03183089
Comparative Study of Rohto Dry-Aid® and Systane® Ultra in Patients With Dry Eye treatment 4 completed NCT06400589
A Study to Evaluate the Efficacy and Safety of Tanfanercept (HL036) in Dry Eye Disease treatment 3 suspended NCT02992392
Comparison of the Clinical Effects of Two Tear Substitutes in Patients With Dry Eye Syndrome treatment Not Available unknown_status NCT00781092
A Prospective, Randomized, Double-Masked, Single Center, Clinical Comparison of the Use of Systane Ultra in the Management of Dry Eyes in Bilateral Eyes No drug interventions treatment 4 completed NCT05505292
Lifitegrast 5% for the Treatment of Dry Eye In Habitual Soft Contact Lens Wearers treatment 4 completed NCT02116244
Civamide Nasal Solution for the Treatment of Dry Eye treatment 2 completed NCT02493244
Lipid Layer Thickness Pre and Post Lid Scrubs With Cliradex No drug interventions basic_science Not Available completed NCT01206244
Diurnal Variation of Tear Meniscus and Tear Osmolarity No drug interventions Not Available Not Available completed NCT03226444
Lacripep™ in Subjects With Dry Eye Associated With Primary Sjögren's Syndrome treatment 1 / 2 completed NCT06346340
A Study to Evaluate the Effect of Miebo™ on Preoperative Biometry/Keratometry and Postoperative Refractive Accuracy treatment 4 recruiting NCT03785340
Study of Brimonidine Tartrate Nanoemulsion Eye Drop Solution in the Treatment of Dry Eye Disease (DED) treatment 3 completed NCT02481167
Evaluation of Meibomian Gland Dysfunction in Chinese Old Patients No drug interventions Not Available Not Available unknown_status NCT05120401
Causal Relationship Between Dry Eye and Accommodative Spasm No drug interventions Not Available Not Available recruiting NCT01139372
An Evaluation of the Daytime Use of an Investigational Lubricant Eye Drop No drug interventions treatment Not Available completed NCT00840268
A Study of Hydroxypropyl Guar Galactomannan 0.25% (HPGG) Versus Vehicle in Dry Eye Patients No drug interventions treatment 2 completed NCT01061268
A Clinical Evaluation Pilot Study of the Efficacy of Blink® Tears Lubricant Eye Drops for the Relief of Dry Eye Symptoms Following Implantation of Tecnis® Multifocal Introcular Lens treatment 4 completed NCT00848068
Evaluation of FID 114657 on Tear Film Lipid Layer Thickness No drug interventions treatment Not Available completed NCT01239069
Safety and Efficacy Study of DE-110 Ophthalmic Suspension for the Treatment of Dry Eye Disease No drug interventions treatment 2 completed NCT02160769
Tear Layer Lipid Thickness in Pterygium Patient Before and After Surgery No drug interventions Not Available Not Available completed NCT05945069
Feasibility of Dynamic Muscle Stimulation + Radiofrequency for Improving Blink Quality in Subjects With Dry Eye Disease No drug interventions treatment Not Available recruiting NCT04458012
Epidemiological Study of Dry Eye Disease in Stavanger: Dry Eye Disease in Patients Treated With Intravitreal Injections No drug interventions Not Available Not Available unknown_status NCT00406510
Comparison of Frequency of Use of Optive and Systane Not Available 4 completed NCT04081610
Clinical Trial to Evaluate the Safety and Tolerability of Lagricel® Ofteno Multi-dose Ophthalmic Solution treatment 1 completed NCT01199510
Efficacy Evaluation of SYSTANE® ULTRA in Patients Scheduled for Cataract Surgery No drug interventions treatment 4 completed NCT03952481
Effect of Lifitegrast 5% on Tear Film Markers diagnostic 4 withdrawn NCT03345381
Impact of Breathing Exercises and Meditation on Quality of Life in Dry Eye Disease Patients: A Pilot Study No drug interventions supportive_care Not Available unknown_status NCT05859295
Evaluation of Low-Level Light Therapy on Meibomian Glands Study No drug interventions basic_science Not Available completed NCT04949295
Evaluation of Ocular Surface in Hemodialysis Patients by Ocular Surface Analyzer No drug interventions Not Available Not Available completed NCT01441895
Corneal Sensation and Incidence of Dry Eye Post Refractive Cataract Extraction With FemtoSecond Laser No drug interventions Not Available Not Available unknown_status NCT05605314
Clinical Cohort Study in Patients With Different Subtypes of Primary Sjogren Syndrome Related Dry Eye No drug interventions Not Available Not Available recruiting NCT01363414
Sodium Hyaluronate and Wavefront Aberrations in Dry Eyes treatment Not Available completed NCT04706455
Effect of Artificial Tears on the Parameters of the Eye and Its Impact on IOL Power Calculation for Cataract Surgery No drug interventions diagnostic Not Available unknown_status NCT00673855
Acute Comfort of Lubricant Eye Drops FID 112903 No drug interventions treatment Not Available completed NCT05481450
Efficacy and Safety Safety of Nutritears® in Adults With Dry Eye Syndrome No drug interventions treatment Not Available completed NCT06565650
A Study to Evaluate Corneal Endothelial Cell Density (ECD) in Subjects With Dry Eye Disease (DED) Administering Miebo® (Perfluorohexyloctane Ophthalmic Solution) for 12 Months. treatment 4 recruiting NCT03833908
Evaluation of the Performance of MAF-1217 on Cataract Surgery No drug interventions treatment Not Available completed NCT02717208
Phase 1 Study for Safety and Tolerability of HL036 No drug interventions treatment 1 completed NCT05737108
Bilberry-containing Capsules for Dry Eye Mitigation No drug interventions treatment Not Available recruiting NCT06043908
The Effect of 0.05% CsA Eye Drops on Post-refractive Surgery Dry Eye treatment 4 recruiting NCT05161208
OC-01 (Varenicline) Nasal Spray and Dry Eye Signs and Symptoms in Daily Disposable Contact Lens Wearers treatment 4 completed NCT06392438
Cyclosporine and Intense Pulsed Light for Dry Eye in Contact Lens Users treatment 3 recruiting NCT00560638
Loteprednol Etabonate Opthalmic Suspension for the Treatment of Dry Eye treatment 2 completed NCT03180047
Dry Eye Symptom Relief Assessment With Use of TrueTear in a Controlled Adverse Environment No drug interventions treatment Not Available completed NCT06263998
Clinical Study for the Evaluation of Safety and Tolerability of NCP112 Eye Drops No drug interventions treatment 1 recruiting NCT04877483
To Evaluate the Short-term and Long Term Efficacy of Acupuncture in Ocular and Oral Dryness Symptoms of Dry Eye Syndrome No drug interventions treatment Not Available recruiting NCT01089985
Use of Autologous Serum Eye-drops as Tears in Patients With Recalcitrant Dry Eye treatment 1 completed NCT05656196
VGH-DESJS-1 in Ocular and Oral Dryness Symptoms of Dry Eye Syndrome and Sjögren's Syndrome No drug interventions other Not Available completed NCT06475027
Exosome-miRNA and Transcriptome Profiling of Dry Eye Syndrome and Sjogren's Syndrome No drug interventions Not Available Not Available not_yet_recruiting NCT04636372
Effect of Meibomian Gland Related Therapy on the Morphology of Meibomian Gland No drug interventions treatment Not Available withdrawn NCT03753893
Ocular Manifestations in Rheumatic Diseases No drug interventions Not Available Not Available completed NCT02655432
Performance of a Photoscreener for Vision Screening in a Haitian Pediatric Population No drug interventions Not Available Not Available withdrawn NCT00796926
Trial to Compare the Efficacy of Systane Ultra and Refresh Drop in the Treatment of Dry Eye in Asian Eyes treatment 3 completed NCT06515457
A Clinical Trial to Evaluate the Efficacy of an Oral Supplement in Supporting Vision and Eye Health No drug interventions treatment Not Available completed NCT02212301
Comparison of Two Marketed Lenses in a Controlled Environment No drug interventions treatment Not Available completed