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Displaying results 1591 - 1600 of 8967 in total
  1. Drug

    Trandolapril

    go.drugbank.com/drugs/DB00519
    ApprovedInvestigational

    It is metabolized to its biologically active diacid form, trandolaprilat, in the liver. … Trandolaprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).

    Categories: Antihypertensive Agents Indicated for Hypertension
  2. Target

    Sequestosome-1

    go.drugbank.com/bio_entities/BE0014160
    TargetHumans

    Also required to recruit ubiquitinated proteins to PML bodies in the nucleus (PubMed:20168092). … Molecular adapter required for selective macroautophagy (aggrephagy) by acting as a bridge between polyubiquitinated proteins and autophagosomes (PubMed:15340068, PubMed:15953362, PubMed:16286508, PubMed

    Synonyms: Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa
  3. Drug

    Inulin

    go.drugbank.com/drugs/DB00638
    ApprovedInvestigationalNutraceutical

    Since it is hydrolyzable to fructose, it is classified as a fructosan. It has been used in physiologic investigation for determination of the rate of glomerular function.

    Categories: Tests for Renal Function and Ureteral Injuries, Compounds used in a research, industrial, or household setting
  4. Drug

    Aminophylline

    go.drugbank.com/drugs/DB01223
    ApprovedInvestigational

    Similar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma, chronic bronchitis, and COPD.

    Categories: Drugs for Obstructive Airway Diseases, Compounds used in a research, industrial, or household setting
  5. Indication

    Salt-losing Androgenital syndrome

    go.drugbank.com/conditions/DBCOND0123106
    Drugs: Fludrocortisone
    Synonyms: Salt-losing Androgenital syndrome
  6. Drug

    Chlorthalidone

    go.drugbank.com/drugs/DB00310
    ApprovedInvestigational

    Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. … In addition to its antihypertensive effects, chlorthalidone has also been shown to decrease platelet aggregation and vascular permeability, as well as promote angiogenesis in vitro, which is thought to

    Mixtures: ATENOLOL CO RATIO 100/25MGCategories: Antihypertensive Agents Indicated for Hypertension
  7. Drug

    Taurocholic acid

    go.drugbank.com/drugs/DB04348
    Approved

    Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.

    Mixtures: Lax-BO Tab, Herbalax Forte No 70 TabCategories: Compounds used in a research, industrial, or household setting
  8. Drug

    Gastric intrinsic factor

    go.drugbank.com/drugs/DB09349
    Approved

    responsive to oral iron therapy. … However, it is currently in the marketed (but unapproved) product Hematogen in combination with cyanocobalamin (synthetic Vitamin B12), ferrous fumarate, and ascorbic acid for the treatment of anemias

    Mixtures: TL-Icon
  9. Drug

    Clotiazepam

    go.drugbank.com/drugs/DB01559
    ApprovedIllicit

    Clotiazepam is a thienodiazepine, not approved for sale in the U.S. or Canada, but has been approved in the U.K. It is a schedule IV drug in Canada.

  10. Drug

    Ursodeoxycholic acid

    go.drugbank.com/drugs/DB01586
    ApprovedInvestigational

    [A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years. … [A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary biliary cirrhosis in 1996.

    Mixtures: BAMBOO SALT Eunganggo Jook Yeom, BAMBOO SALT Eunganggo Jook Yeom ToothpasteProducts: T-RUXICO