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rsPSMA Vaccine
go.drugbank.com/drugs/DB06361ApprovedWithdrawnProstate-specific membrane antigen (PSMA) is an ∼100 kDa transmembrane glycoprotein that is abundantly and preferentially expressed in prostate cancer, including recurrent and hormone-refractory cases. rsPSMA Vaccine is a subunit vaccine...
Nitazoxanide
go.drugbank.com/drugs/DB00507ApprovedInvestigationalVet approvedNitazoxanide belongs to the class of drugs known as _thiazolides_. … Recently, this drug has been studied as a broad-spectrum antiviral agent due to its ability to inhibit the replication of several RNA and DNA viruses [A31977].
Alimemazine
go.drugbank.com/drugs/DB01246ApprovedVet approvedWithdrawnA phenothiazine derivative that is used as an antipruritic.
Chlorpropamide
go.drugbank.com/drugs/DB00672ApprovedWithdrawnChlorpropamide is not recommended for the treatment of NIDDM as it increases blood pressure and the risk of retinopathy (UKPDS-33). … Up to 80% of the single oral dose of chlorpropramide is metabolized, likely in the liver; 80-90% of the dose is excreted in urine as unchanged drug and metabolites.
Ademetionine
go.drugbank.com/drugs/DB00118ApprovedInvestigationalNutraceuticalPhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Fluocinolone acetonide
go.drugbank.com/drugs/DB00591ApprovedInvestigationalVet approvedFluocinolone acetonide, with the formula 6-alpha, 9-alpha-difluoro-16-alpha, 17 alpha-acetonide, is a corticosteroid that presents a high lipophilicity. It has been used extensively in dermatological preparations and it has also been inv...
Nuvaxovid
go.drugbank.com/drugs/DB15810ApprovedInvestigational[L49111] In the fall of 2024, an updated formulation covering the Omicron JN.1 subvariant was approved for use in Canada and the US.[L51394,L51399]
Ferric pyrophosphate citrate
go.drugbank.com/drugs/DB13995ApprovedFree iron presents several side effects as it can catalyze free radical formation and lipid peroxidation as well as the presence of interactions of iron in plasma. … [A31979] FPC is categorized in Japan as a second class OTC drug.
Monobenzone
go.drugbank.com/drugs/DB00600ApprovedWithdrawnMonobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water.
Agmatine
go.drugbank.com/drugs/DB08838ExperimentalAs an experimental drug, agmatine is being studied for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection (stroke, severe CNS injuries, epilepsy, glaucoma … As an investigational drug, it is being studied in a non-blinded prospective case study in the United States looking at patients who have been diagnosed with small fiber peripheral neuropathy between the