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Displaying results 1621 - 1630 of 1777 in total
  1. Drug

    ZYCOV-D

    go.drugbank.com/drugs/DB15892
    Experimental

    Once the plasmid DNA is introduced into host cells and the viral protein is translated, it elicits a strong immune response, stimulating the humoral and cellular components of the immune system[L16503]

  2. Target

    NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

    go.drugbank.com/bio_entities/BE0000027
    TargetHumans

    May be the terminally assembled subunit of Complex I … Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.

    Synonyms: Complex I-9kD
  3. Target

    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

    go.drugbank.com/bio_entities/BE0000754
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-B17.2
  4. Target

    Phospholipid-transporting ATPase ID

    go.drugbank.com/bio_entities/BE0013936
    TransporterHumans

    Catalytic component of P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of phosphatidylcholine (PC) from the outer to the inner leaflet of the plasma membrane.

    Synonyms: P4-ATPase flippase complex alpha subunit ATP8B2
  5. Target

    Serine/threonine-protein kinase TAO1

    go.drugbank.com/bio_entities/BE0009392
    TargetHumans

    Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator o...

    Synonyms: Thousand and one amino acid protein kinase 1
  6. Drug

    Tunicamycin

    go.drugbank.com/drugs/DB13172
    Experimental

    One member of this family is the enzyme GlcNAc phosphotransferase (GPT), which catalyzes the transfer of N-acetylglucosamine-1-phosphate from UDP-N-acetylglucosamine to dolichol phosphate in the first

  7. Drug

    Finasteride

    go.drugbank.com/drugs/DB01216
    ApprovedInvestigational

    Compared to alpha-blockers that focus on providing the rapid relief of symptoms, 5α-reductase inhibitors aim to target the underlying disease by blocking the effects of the primary androgen involved in

  8. Drug

    Dextromethorphan

    go.drugbank.com/drugs/DB00514
    ApprovedInvestigational

    Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethor...

    Mixtures: Cold & Flu-IN-one, Cold and Flu All In One
  9. Target

    NF-kappa-B inhibitor alpha

    go.drugbank.com/bio_entities/BE0003469
    TargetHumans

    Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL (RELA/p65 and NFKB1/p50) dimers in the cytoplasm by masking their nuclear localization signals (PubMed:1493333, PubMed:36651806, PubMed:7479976). On cellular stimu...

    Synonyms: Major histocompatibility complex enhancer-binding protein MAD3
  10. Drug

    Alprazolam

    go.drugbank.com/drugs/DB00404
    ApprovedIllicitInvestigational

    Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole. Benzodiazepine trea...