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Colistin
go.drugbank.com/drugs/DB00803ApprovedInvestigationalIt is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. … Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Synonyms: Polymyxin EMixtures: Coly-Mycin S, Coly-Mycin SMirabegron
go.drugbank.com/drugs/DB08893ApprovedInvestigational[L32853] An extended-release granule formulation was subsequently granted approval in March 2021 for the treatment of pediatric patients with neurogenic detrusor overactivity. … Mirabegron is a sympathomimetic beta-3 adrenergic receptor agonist used to relax the smooth muscle of the bladder in the treatment of urinary frequency and incontinence.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: MYRBETRIC® 50 MG TABLETAS DE LIBERACION PROLONGADA, MYRBETRIC® 25 MG TABLETAS DE LIBERACION PROLONGADARelapsed Multiple Myeloma
go.drugbank.com/conditions/DBCOND0031510Drugs: Belantamab mafodotin · Carfilzomib · Ciltacabtagene autoleucel · Daratumumab · Dexamethasone · Elranatamab +8 moreSynonyms: Multiple Myeloma in RelapseKeratoconjunctivitis Sicca (KCS)
go.drugbank.com/conditions/DBCOND0105777Drugs: Hydroxypropyl celluloseSynonyms: Keratoconjunctivitis sicca, in Sjögren syndrome, Keratoconjunctivitis sicca, in Sjogren's syndromeMometasone furoate
go.drugbank.com/drugs/DB14512ApprovedInvestigationalVet approvedMometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. … Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications[FDA Label][F4292,F4295].
Mixtures: M-FURO FA %0.1 + %2 KREM, 30 G, DERMOTIL-S® UNGUENTOCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersCentral Diabetes Insipidus
go.drugbank.com/conditions/DBCOND0051168Drugs: DesmopressinSynonyms: DI - Diabetes insipidusPrednisolone
go.drugbank.com/drugs/DB00860ApprovedInvestigationalVet approved[A187463] Prednisolone was granted FDA approval on 21 June 1955.[L9431] … Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.
Synonyms: Predniso(lo)ne, delta(1)-HydrocortisoneInternational brands: Di-Adreson F, Di-Adreson-FCyclosporine
go.drugbank.com/drugs/DB00091ApprovedInvestigationalVet approved[A174049] Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118] … Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions.
Synonyms: Cyclosporin A, Cyclosporine ACategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexAlemtuzumab
go.drugbank.com/drugs/DB00087ApprovedInvestigationalAlemtuzumab is produced in mammalian cell (Chinese hamster ovary) suspension culture in a medium containing neomycin.[L43397] Alemtuzumab was approved by the FDA in 2001. … Alemtuzumab is a humanized monoclonal antibody specific to lymphocyte antigens.
Synonyms: Campath 1-HProducts: MABCAMPATH INF SOL ICIN 30 MG/ML KONS 1 ML 3 FLK (10 MG/ML KONSANTRE 3 AMP), LEMTRADA®Pentetic acid
go.drugbank.com/drugs/DB14007ApprovedInvestigational[A32501] It is currently considered, in all the dosage forms, as a member of the list of approved inactive ingredients for drug products by the FDA. … [L2242] DPTA was developed by the pharmaceutical company CIS US and FDA approved on April 14, 2004.[L1469]
Synonyms: DTP-ACategories: Compounds used in a research, industrial, or household setting