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Bordetella pertussis pertactin antigen
go.drugbank.com/drugs/DB10789ApprovedInvestigationalBordetella pertussis pertactin antigen is a vaccine for the prophylaxis of whooping cough that contains pertactin, a membrane-associated antigen of Bordetella pertussis [A31248].
Mixtures: -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE, Covaxis Injektionssuspension in einer FertigspritzeEmtricitabine
go.drugbank.com/drugs/DB00879ApprovedInvestigationalin high risk adolescents and adults. … Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults[L9019] or combined with [tenofovir alafenamide] for the prevention of HIV-1 infection
Mixtures: TOLAK® E 300/200, TOLAK® E 300/200Categories: Antivirals used in combination for the treatment of HIV infections, MATE 1 SubstratesSimethicone
go.drugbank.com/drugs/DB09512ApprovedInvestigational[A228308] It has a favourable safety profile as it is not systemically absorbed.[A228308] Simethicone has been in use since the 1940s[A228303] but was granted FDA approval in 1952.[A228308] … Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination.
Mixtures: E-Z-GAS II GRANULES, M A L D I MCategories: Compounds used in a research, industrial, or household settingPertussis vaccine
go.drugbank.com/drugs/DB15274ApprovedInvestigationalPertussis vaccine is under investigation in clinical trial NCT01698346 (Pertussis (Tdap) Vaccination in Pregnancy).
Mixtures: Boostrix Injektionssuspension in einer Fertigspritze, dTaP Booster Injektionssuspension in einer FertigspritzeProducts: Pertussis Vaccine 4 Protect UnitIngenol mebutate
go.drugbank.com/drugs/DB05013ApprovedWithdrawnPEP005 also has potent anti-leukemic effects, inducing apoptosis in myeloid leukemia cell lines and primary AML cells at nanomolar concentrations. … Ingenol mebutate was approved by the FDA in January 2012, and it is marketed under the name Picato®. Picato gel is indicated for the topical treatment of actinic keratosis.
Synonyms: 3-Angeloylingenol, 3-Ingenyl angelateOmeprazole Action Pathway (old)
smpdb.ca/view/SMP0000226Drug actionLosec and Zegerid, is a proton pump inhibitor (PPI) class drug that suppresses the final step in gastric acid production, and was the first proton pump inhibitor to e developed. … In this pathway, omeprazole is taken orally and is oxidized in the stomach to form the active metabolite of omeprazole.
Enzymes: Potassium voltage-gated channel subfamily E member 2Lansoprazole Action Pathway (old)
smpdb.ca/view/SMP0000227Drug actionIn this pathway, lansoprazole is taken orally and is oxidized in the stomach to form the active metabolite of lansoprazole. … Lansoprazole, sold as Prevacid, is a proton pump inhibitor (PPI) class drug that suppresses the final step in gastric acid production.
Enzymes: Potassium voltage-gated channel subfamily E member 2Ranitidine Action Pathway
smpdb.ca/view/SMP0000230Drug actionThe pathway begins in the stomach, where ranitidine inhibits the histamine H2 receptor on the surface of the parietal cell. … Now in the gastric endothelial cell, potassium-transporting ATPase units are inhibited by G-Protein signalling cascade through somatostatin receptor type 4, which is activated by somatostatin.
Enzymes: Potassium voltage-gated channel subfamily E member 2Famotidine Action Pathway
smpdb.ca/view/SMP0000231Drug actionFamotidine (also known as Pepcid) can bind and inhibit histamine H2 receptor on parietal cell's basolateral membrane. Binding of famotidine can effectively inhibit the histamine effects, which lead to reduced nocturnal gastric acid and b...
Enzymes: Potassium voltage-gated channel subfamily E member 2Cimetidine Action Pathway
smpdb.ca/view/SMP0000232Drug actionThis blocks histamine effects, resulting in reduced gastric acid secretion and a reduction in gastric volume and acidity.
Enzymes: Potassium voltage-gated channel subfamily E member 2