Search

Displaying results 1631 - 1640 of 10000 in total
  1. Drug

    Pixantrone

    go.drugbank.com/drugs/DB06193
    ApprovedWithdrawn

    Based on this uncertainty, in 2009, the FDA ultimately rejected Cell Therapeutic's initial application for accelerated approval for pixantrone use in relapsed or refractory NHL. … Another phase III trial, PIX-R, is now ongoing to clarify pixantrones place in therapy. It will compare pixantrone efficacy to that of gemcitabine. [2]

    Categories: Topoisomerase II Inhibitors
  2. Drug

    (R)-Gossypol

    go.drugbank.com/drugs/DB17379
    Investigational

    (R)-Gossypol is the R-isomer of [Gossypol].

    Synonyms: Gossypol r-form, (R)-Gossypol
  3. Drug

    Tamsulosin

    go.drugbank.com/drugs/DB00706
    ApprovedInvestigational

    [Label] Antagonism of these receptors leads to relaxation of smooth muscle in the prostate and detrusor muscles in the bladder, allowing for better urinary flow. … [Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy.

    Categories: Drugs Used in Benign Prostatic HypertrophySynonyms: (R)-(−)-tamsulosin, (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide
  4. Target

    G protein-coupled bile acid receptor 1

    go.drugbank.com/bio_entities/BE0005788
    TargetHumans

    G protein-coupled receptor for bile acid (PubMed:12419312, PubMed:12524422, PubMed:32698187, PubMed:32747649, PubMed:35858343). … Involved in bile acid promoted GLP-1 secretion (By similarity)

    Synonyms: Membrane-type receptor for bile acids
  5. Drug

    Vibegron

    go.drugbank.com/drugs/DB14895
    ApprovedInvestigational

    On December 23, 2020, vibegron was approved for the same indication in adults. It is available as oral tablets under the market name GEMTESA. … [L28305] Vibegron was first approved in Japan in September 2018 for the treatment of overactive bladder,[A226050] a condition associated with distressing symptoms of urge urinary incontinence, urgency,

    Categories: Drugs for Urinary Frequency and Incontinence
  6. Indication

    Psychophysiological Disorders

    go.drugbank.com/conditions/DBCOND0172355
    Drugs: Melperone
    Synonyms: Psychosomatic factor in physical condition, NOS, Psychosomatic factor in physical condition (finding)
  7. Drug

    Cetyl alcohol

    go.drugbank.com/drugs/DB09494
    Approved

    According to the FDA Code of Federal Regulations, cetyl alcohol is a safe synthetic fatty acid in food and in the synthesis of food components under the condition that it contain not less than 98 percent … Cetyl alcohol is present in a waxy white powder or flake form at room temperature, and is insoluble in water and soluble in alcohols and oils [A32209].

  8. Drug

    Clotiazepam

    go.drugbank.com/drugs/DB01559
    ApprovedIllicit

    Clotiazepam is a thienodiazepine, not approved for sale in the U.S. or Canada, but has been approved in the U.K. It is a schedule IV drug in Canada.

  9. Drug

    Bevantolol

    go.drugbank.com/drugs/DB01295
    Investigational

    Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension. … Mechanism of Action Animal experiments confirm both agonist and antagonist effects on alpha-receptors, in addition to antagonist activity at beta-1 receptors.

    Products: BETA FORM
  10. Drug

    Ferumoxytol

    go.drugbank.com/drugs/DB06215
    ApprovedInvestigational

    [L54501] The drug remains approved in the US, with a new indication being approved in October of 2025 for Ferumoxytol's use as a diagnostic agent for MRI of the brain. … In January of 2015, the EMA withdrew marketing authorisation for Rienso (ferumoxytol) due to safety concerns.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Ferumoxytol non-stoichiometric magnetite