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Etanercept
go.drugbank.com/drugs/DB00005ApprovedInvestigationalEtanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids. … It is used to treat or manage a variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and juvenile idiopathic poly-articular arthritis (JIA).
Products: BENEPALI 50MG ILO I E FER, ENBREL ® 50 MG POLVO Y SOLVENTE PARA SOLUCION INYECTABLEUrokinase
go.drugbank.com/drugs/DB00013ApprovedInvestigationalWithdrawn[A191943] Urokinase remains connected between these 2 chains by a sulfhydryl bond.[A191943] Urokinase was granted FDA approval on 16 January 1978.[L12138]
Products: UROKINASE KGCC INJ. 250000 IU FLAKON, 1 ADET, UROKINASE KGCC INJ. 500000 IU FLAKON, 1 ADETThyrotropin alfa
go.drugbank.com/drugs/DB00024ApprovedInvestigationalVet approvedcontaining one N-linked glycosylation site. … It is a heterodimeric glycoprotein comprised of two non-covalently linked subunits, an alpha subunit of 92 amino acid residues containing two N-linked glycosylation sites and a beta subunit of 112 residues
Products: THYROGEN®, THYROGEN(R)Anakinra
go.drugbank.com/drugs/DB00026ApprovedInvestigationalAnakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist (IL-1Ra) composed of 153 amino acid residues. … This drug binds to the IL-1 receptor, competing with and inhibiting the activity of IL-1 alpha and beta.
Categories: Interleukin-1 Receptor AntagonistSynonyms: Interleukin-1 receptor antagonist anakinraAldesleukin
go.drugbank.com/drugs/DB00041ApprovedInvestigationalAldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. … This recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon
Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 CYP3A InhibitorsSynonyms: 125-L-Serine-2-133-interleukin 2, 125-L-serine-2-133-interleukin 2 (human reduced)Omalizumab
go.drugbank.com/drugs/DB00043ApprovedInvestigationalOmalizumab is a recombinant DNA-derived humanized monoclonal antibody directed against human immunoglobulin E (IgE). … [L50482] It is used to treat a range of immune and inflammatory conditions, including allergies, urticaria, and asthma.[A263507]
Products: XOLAIR ® 150 MG, XOLAIR ® SOLUCIÓN INYECTABLELutropin alfa
go.drugbank.com/drugs/DB00044ApprovedInvestigationalLutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units.
Mixtures: PERGOVERIS 150 IU/75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET, PERGOVERIS 150 IU/75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 3 ADETProducts: LUVERIS 75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADETAdalimumab
go.drugbank.com/drugs/DB00051ApprovedInvestigationalA high-concentration, citrate-free formulation of Cyltezo® (adalimumab-adbm), a biosimilar to Humira®, was approved by the FDA in May 2024 for the treatment of multiple chronic inflammatory diseases. … A biosimilar marketed as Hyrimoz, a high-concentration formulation of adalimumab, is also available.[L45643,L45818].
Products: AMGEVITA 40MG ILO I E FER, AMGEVITA 40MG ILO I E PENSomatotropin
go.drugbank.com/drugs/DB00052ApprovedInvestigational[A228183, L31508] Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone that contains 191 amino acid residues with a molecular weight of 22 kDa. … [A228188] Recombinant growth hormone is available as a subcutaneous injection for children and adults under a wide variety of brand names.
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 InducersProducts: SAIZEN 4 IU FLAKON, 1 ADET, SAIZEN®6 MG /1.03ML( 5.83MG/ML)Imiglucerase
go.drugbank.com/drugs/DB00053ApprovedInvestigationalHuman Beta-glucocerebrosidase or Beta-D-glucosyl-N-acylsphingosine glucohydrolase E.C. 3.2.1.45. 497 residue protein with N-linked carbohydrates, MW=59.3 kD.
Products: CEREZYME 200 U INFUZYONLUK KONSANTRE ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 1 ADET, CEREZYME 400 U/10 ML İNFÜZYONLUK KONSANTRE ÇÖZELTİ İÇİN TOZ