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Ceritinib
go.drugbank.com/drugs/DB09063ApprovedInvestigationalCeritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) following failure (secondary to resistance or intolerance) of … Ceritinib exerts its therapeutic effect by inhibiting autophosphorylation of ALK, ALK-mediated phosphorylation of the downstream signaling protein STAT3, and proliferation of ALK-dependent cancer cells
Products: ZYKADIA 150 MG, ZYKADIA 150 MG KAPSÜL, 150 ADETLebrikizumab
go.drugbank.com/drugs/DB11914ApprovedInvestigationalyears and older with a body weight of at least 40 kg. … This approval is based on the positive results obtained from the Phase 3 studies ADvocate 1 and ADvocate 2, where nearly 80% of patients taking lebrikizumab either as monotherapy or combination therapy
Amrinone
go.drugbank.com/drugs/DB01427ApprovedWithdrawnAmrinone (or inamrinone) is a type 3 pyridine phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure.
Categories: Compounds used in a research, industrial, or household settingBromothalonil
go.drugbank.com/drugs/DB14199ApprovedIt is also a known allergen and dermatological irritant that has been banned in many EU countries due to increasing rates of contact allergy [A34322].
Categories: Compounds used in a research, industrial, or household settingCabotegravir
go.drugbank.com/drugs/DB11751ApprovedInvestigationalCabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, [rilpivirine]. … [A227668,L31193] Cabotegravir was granted FDA approval on 21 January 2021 in combination with rilpivirine to treat HIV-1 infection in virologically suppressed individuals.
Products: Vocabria 30 mg Film Kaplı Tablet, 30 ADET, Vocabria 400 mg/2 ml Enjeksiyonluk Uzatılmış Salımlı Süspansiyon, 1 ADETPropranolol
go.drugbank.com/drugs/DB00571ApprovedInvestigational[L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.[L6904] … Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors.
Mixtures: ARTENSOL® H 40 MG TABLETASSynonyms: 1-(isopropylamino)-3-(1-naphthyloxy)propan-2-olSilver sulfadiazine
go.drugbank.com/drugs/DB05245ApprovedInvestigationalVet approvedSilver sulfadiazine is a sulfa derivative topical antibacterial used primarily on second- and third-degree burns.
Mixtures: SİLVERDİN PLUS %1 + %5 KREM, 50 GCategories: combinations of sulfonamidesPermethrin
go.drugbank.com/drugs/DB04930ApprovedInvestigationalA pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Categories: Compounds used in a research, industrial, or household settingProducts: Kwaskab %5 Krem (30 G), Kwaskab %5 Krem (60 G)Tebentafusp
go.drugbank.com/drugs/DB15283ApprovedInvestigationalof action. … Even after surgical ablation or removal of the ocular tumour, almost 50% of patients with uveal melanoma develop metastatic disease.
Porfimer sodium
go.drugbank.com/drugs/DB00707ApprovedInvestigationalThe purified component of hematoporphyrin derivative, it consists of a mixture of oligomeric porphyrins. … It is the first drug to be approved in the use of photodynamic therapy in the United States.
Categories: Heterocyclic Compounds with 4 or More Rings