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Displaying results 1641 - 1650 of 10000 in total
  1. Drug

    Aldesleukin

    go.drugbank.com/drugs/DB00041
    ApprovedInvestigational

    This recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon … Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene.

    Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 CYP3A InhibitorsSynonyms: ILT-101, 125-L-Serine-2-133-interleukin 2
  2. Drug

    Asenapine

    go.drugbank.com/drugs/DB06216
    ApprovedInvestigational

    It is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009.

    Categories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsProducts: SYCREST 5MG DILALTI TABLET, 100 TABLET, SYCREST 5MG DILALTI TABLET, TABLET, 20 ADET
  3. Drug

    Magnesium cation

    go.drugbank.com/drugs/DB01378
    ApprovedInvestigationalNutraceuticalWithdrawn

    Magnesium hydroxide is used primarily in "Milk of Magnesia", a white aqueous, mildly alkaline suspension of magnesium hydroxide formulated at about 8%w/v. … draw fluids from the body and to retain those already within the lumen of the intestine, serving to distend the bowel, thus stimulating nerves within the colon wall, inducing peristalsis and resulting in

    Synonyms: Magnesium, ion(Mg2+)Mixtures: MAGVEL 365 MG GRANÜL İÇEREN SAŞE, 20 ADET, KALSİMAG-D3 1000 MG/300 MG/880 IU EFERVESAN GRANÜL, 30 ADET
  4. Drug

    Bromocriptine

    go.drugbank.com/drugs/DB01200
    ApprovedInvestigationalWithdrawn

    [L43942,L43947] It continues to be used for the indications mentioned above. … It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia.

    Synonyms: 2-bromo-α-ergokryptin, 2-bromo-α-ergocryptineCategories: Adrenergic alpha-2 Receptor Agonists, Heterocyclic Compounds with 4 or More Rings
  5. Drug

    Octenidine

    go.drugbank.com/drugs/DB12624
    Investigational

    Octenidine is under investigation in clinical trial NCT02697162 (Antiseptic-coated Intermittent Urinary Catheter).

    Mixtures: Linola sept 1 mg/g + 10 mg/g Wund-Gel, Linola sept 1 mg/g + 20 mg/g Wund-Spray zur Anwendung auf der Haut, LösungProducts: OSEPTIN %0.1 ANTISEPTIK COZELTI, 500 ML, OSEPTIN %0.1 ANTISEPTIK COZELTI, 1000 ML
  6. Drug

    Amino acids

    go.drugbank.com/drugs/DB09393
    Investigational

    Mixture of amino acids ; used for parenteral nutrition in infants.

    Mixtures: Clinimix 5 % G-E - Infusionsbeutel, Clinimix 3 % G-E - InfusionsbeutelProducts: AVONIL 500 MG 900 TABLET, AMINOVENOS-N PED % 10 İNTRAVENÖZ İNFÜZYON SOLÜSYONU, 100 ML
  7. Drug

    Zanamivir

    go.drugbank.com/drugs/DB00558
    ApprovedInvestigational

    A guanido-neuraminic acid that is used to inhibit neuraminidase.

    Synonyms: 4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid, 5-acetamido-2,6-anhydro-3,4,5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic acidProducts: CIPROFLOXACINO 500 MG TABLETAS RECUBIERTAS, RELENZA ROTADISK 5 mg/dose
  8. Drug

    Fomepizole

    go.drugbank.com/drugs/DB01213
    ApprovedVet approved

    Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. … Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.

    Synonyms: 4-methylpyrazol, 4-methylpyrazoleCategories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 Substrates
  9. Drug

    Naphazoline

    go.drugbank.com/drugs/DB06711
    Approved

    It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807]. … Naphazoline was first developed in 1942 as a nasal formulation for congestion[A176609].

    Mixtures: SULFARHIN BURUN MERHEMI, 20 G, OSMOCROM-N ®Categories: Adrenergic alpha-2 Receptor Agonists
  10. Drug

    Ulipristal

    go.drugbank.com/drugs/DB08867
    ApprovedInvestigational

    debated due to ethical concerns related to abortion (Rosato et al, 2016). … Ulipristal is currently recommended as first line therapy for emergency contraception, due to improved efficacy and similar side effect profile as compared to the traditional use of levonorgestrel or the

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ESMYA® 5 MG COMPRIMIDOS, Femke 30 mg Filmtablette