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Displaying results 1641 - 1650 of 2507 in total

Drug
Amcinonide
go.drugbank.com/drugs/DB00288
Approved
Amcinonide is a corticosteroid.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
Drug
Etonogestrel
go.drugbank.com/drugs/DB00294
ApprovedInvestigational
Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel. The first product including etonogestrel was developed by the Merck subsidiary Organon and F...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
Drug
Bupivacaine
go.drugbank.com/drugs/DB00297
ApprovedInvestigational
Bupivacaine is a widely used local anesthetic agent.
Mixtures: P-Care M, P-Care MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
Drug
Penciclovir
go.drugbank.com/drugs/DB00299
Approved
Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
Drug
Candicidin
go.drugbank.com/drugs/DB01152
ApprovedInvestigationalWithdrawn
Candicidin is an antibiotic obtained from a streptomyces (Streptomyces griseus) and active against some fungi of the genus Candida (C. albicans). Candicidin is administered intravaginally in the treatment of vulvovaginal candidiasis.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors
Drug
Gemifloxacin
go.drugbank.com/drugs/DB01155
ApprovedInvestigational
Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. It is available in oral formulations. Gemi...
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
Drug
Cyclizine
go.drugbank.com/drugs/DB01176
ApprovedWithdrawn
A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (From Martindale, The Extra Pharmacopoeia, 30th ed, p935)
Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
Drug
Clindamycin
go.drugbank.com/drugs/DB01190
ApprovedInvestigationalVet approved
Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms as well as topically for acne vulgaris. It has a relatively narrow spectrum of activity tha...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Clindacin P
Drug
Dexfenfluramine
go.drugbank.com/drugs/DB01191
ApprovedIllicitWithdrawn
Dexfenfluramine, also marketed under the name Redux, is a serotoninergic anorectic drug. For a fairly limited time during the middle of the nineties, the US FDA had approved it for use in managing weight loss. However, following multiple...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
Drug
Acebutolol
go.drugbank.com/drugs/DB01193
ApprovedInvestigational
A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates