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Brentuximab vedotin
go.drugbank.com/drugs/DB08870ApprovedInvestigationalIn this type of lymphoma, large, abnormal lymphocytes (a type of white blood cell) are found in the lymph nodes called Reed-Sternberg cells. … In January 2012, the drug label was revised with a boxed warning of a condition known as progressive multifocal leukoencephalopathy and death due to opportunistic JC virus infection post-treatment.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: ADCETRIS 50 MG IV INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇIN TOZ IÇEREN FLAKON ,FLAKON, 1 ADET, ADCETRIS®Spectinomycin
go.drugbank.com/drugs/DB00919ApprovedVet approvedWithdrawnAn antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 3-RingProducts: Trobicin Inj 400mg/ml, Spectro 5% w/v Oral SolutionHaemophilus influenzae type B capsular polysaccharide meningococcal outer membrane protein conjugate antigen
go.drugbank.com/drugs/DB10342ApprovedInvestigationalHaemophilus influenzae type b capsular polysaccharide meningococcal outer membrane protein conjugate antigen is a vaccine containing outer membrane antigen extracted from *Haemophilus influenzae*.
Synonyms: Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine, Haemophilus influenzae type B capsular polysaccharide meningococcal outer membrane protein conjugate antigenMixtures: HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET, HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETAprotinin
go.drugbank.com/drugs/DB06692ApprovedInvestigationalWithdrawnAprotinin is a protein-based drug that is also known as bovine pancreatic trypsin inhibitor (BPTI). … Since it demonstrates the capacity to slow fibrinolysis, it has been employed to reduce bleeding during complex surgery such as heart and liver surgery.
Mixtures: ŞTİ.EL LYO 1 ML TROMBIN ÇÖZELTİSİ VE 1 ML FIBRINOJEN ÇÖZELTİSİ ICEREN IKI BILESENLI FIBRIN YAPISTIRICI, SET 1 (2 İĞNE+2 ENJEKTÖR) VE SET 2 (2 İĞNE +2 ENJEKTÖR+1 ENJEKTÖR KLİPSİ+2 BİRLEŞTİRME PARÇASI+ 4, TISSEEL FIBRIN SEALANT VH S/D (FROZEN)Products: Trasylol Inj 10000 Kiu/mlSodium iodide
go.drugbank.com/drugs/DB11119ApprovedInvestigationalSodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition [L2065] but is more commonly used in veterinary medicine. … Sodium iodide is a water-soluble ionic compound with a crystal lattice.
Mixtures: FERTOMCIDINA U, FERTOMCIDINA UProducts: Micro I, Sodium Iodide Inj 100mg/mlMuromonab
go.drugbank.com/drugs/DB00075ApprovedInvestigationalWithdrawnMore specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method. … Muromonab is 93% monomeric immune globulin G type 2a (IgG2a).
Categories: Immunoglobulin GProducts: Orthoclone Okt 3 Sterile Solution IV 1mg/mlReteplase
go.drugbank.com/drugs/DB00015ApprovedInvestigationalWithdrawnRetavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. … Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA.
Synonyms: Human t-PA (residues 1-3 and 176-527)Products: RAPILYSIN 10 U IV ENJ. ICIN STERIL LIYOFILIZE TOZ ICEREN FLAKON, 2 ADETBenzyl benzoate
go.drugbank.com/drugs/DB00676ApprovedIt is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. … Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.
Categories: Compounds used in a research, industrial, or household settingInternational brands: Acaril-SBuserelin
go.drugbank.com/drugs/DB06719ApprovedInvestigationalIt is used in prostate cancer treatment. … Buserelin is a synthetic peptide analog of the luteinizing hormone-releasing hormone (LHRH) agonist, which stimulates the pituitary gland's gonadotrophin-releasing hormone receptor (GnRHR).
Products: Suprefact Inj 1mg/ml, Suprefact Depot 2 MonthsAlemtuzumab
go.drugbank.com/drugs/DB00087ApprovedInvestigationalThe dose of alemtuzumab used for B-CLL is much higher than that for MS, and also at more frequent dosing.[L43397, L30335] … Alemtuzumab is produced in mammalian cell (Chinese hamster ovary) suspension culture in a medium containing neomycin.[L43397] Alemtuzumab was approved by the FDA in 2001.
Synonyms: Campath 1-HProducts: MABCAMPATH INF SOL ICIN 30 MG/ML KONS 1 ML 3 FLK (10 MG/ML KONSANTRE 3 AMP), LEMTRADA®