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Displaying results 1641 - 1650 of 10000 in total
  1. Drug

    Ramucirumab

    go.drugbank.com/drugs/DB05578
    ApprovedInvestigational

    Ramucirumab is indicated for us in advanced gastric or gastro-esophageal junction adenocarcinoma as a single agent or in combination with paclitaxel after prior fluoropyrimidine- or platinum-containing … VEGFR stimulation also mediates downstream signalling required for angiogenesis and is postulated to be heavily involved in cancer progression, making it a highly likely drug target.

  2. Drug

    Thimerosal

    go.drugbank.com/drugs/DB11590
    Approved

    Although thimerosal is banned in several countries, it continues to be included as a preservative in some vaccines in the United States and many vaccines in the developing world [L1685]. … Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent.

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Galactose

    go.drugbank.com/drugs/DB11735
    ApprovedInvestigationalWithdrawn

    As a naturally occurring sugar, it may be found in a number dairy products. Even then, however, it is not generally used as a sweetener considering it is only about 30% as sweet as sucrose. … Regardless, although it is predominantly used as a pathway to generate glucose fuel for the human body, galactose is involved as an ingredient in some commonly used vaccines and non-prescription products

    Mixtures: Levovist - Pws IV (4g Granules /vial)
  4. Pathway

    Joubert Syndrome

    smpdb.ca/view/SMP0000582
    Disease

    The symptoms affect a variety of body parts in the patient, including apnea, ataxia brought on by hypotonia, abnormal eye movements and intellectual disability. … Joubert syndrome is a condition in which brain development is not completed as it should be, including the lack or underdevelopment of the part of the brain that regulates balance and coordination and

    Drugs: ATP · Calcium · Magnesium cation · Inositol
    Enzymes: Activating molecule in BECN1-regulated autophagy protein 1
  5. Pathway

    Joubert Syndrome

    smpdb.ca/view/SMP0125809
    Disease

    The symptoms affect a variety of body parts in the patient, including apnea, ataxia brought on by hypotonia, abnormal eye movements and intellectual disability. … Joubert syndrome is a condition in which brain development is not completed as it should be, including the lack or underdevelopment of the part of the brain that regulates balance and coordination and

    Drugs: ATP · Calcium · Magnesium cation · Inositol
    Enzymes: Activating molecule in BECN1-regulated autophagy protein 1
  6. Drug

    Acarbose

    go.drugbank.com/drugs/DB00284
    ApprovedInvestigational

    Acarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines. … Acarbose is therefore used in conjunction with diet, exercise, and other pharmacotherapies for the management of blood sugar levels in patients with type 2 diabetes.

    Categories: Drugs Used in Diabetes
  7. Drug

    Cholestyramine

    go.drugbank.com/drugs/DB01432
    ApprovedInvestigational

    Cholestyramine resin is quite hydrophilic, but insoluble in water. … Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins.

    Categories: Compounds used in a research, industrial, or household setting, Ion Exchange ResinsProducts: COLESTYRAMIN 1A PHARMA 4G, ANTILIP GRANULADO EN SACHET
  8. Drug

    Isosulfan blue

    go.drugbank.com/drugs/DB09136
    ApprovedInvestigational

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    Delamanid

    go.drugbank.com/drugs/DB11637
    ApprovedInvestigational

    It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a combination regimen. … Multidrug-resistant tuberculosis may also require more than 2 years of chemotherapy and second-line therapies with narrow therapeutic index [A31968].

  10. Drug

    Butalbital

    go.drugbank.com/drugs/DB00241
    ApprovedIllicit

    [L10370] Butalbital‐containing analgesics can also produce a drug‐induced headache in addition to tolerance and dependence. … There have not been clinical trials that evaluate the clinical efficacy of butalbital in migraines [A177754] thus it is not indicated for such condition.

    Mixtures: Vtol LQ, Alagesic LQSynonyms: 5-allyl-5-(2'-methyl-n-propyl) barbituric acid