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Satralizumab
go.drugbank.com/drugs/DB15762ApprovedInvestigationalSatralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL-6) receptors, similar to [tocilizumab], which is produced in Chinese hamster ovary cells and based on … Enspryng®, a satralizumab formulation developed by Chugai Pharmaceutical and Roche,[L15536] is uniquely formulated with "recycling antibody technology" whereby the association of satralizumab to IL-6 receptors
Categories: Interleukin-6 Receptor AntagonistSynonyms: Humanised anti-IL-6 receptor monoclonal antibodyVecuronium
go.drugbank.com/drugs/DB01339ApprovedInvestigationalA non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium.
Categories: P-glycoprotein substratesProducts: BLOK-L 4 MG IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 ADET, NORCUR®Potassium cation
go.drugbank.com/drugs/DB01345ApprovedPotassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. … The cell membrane potential created by potassium and sodium ions allows the cell generate an action potential—a "spike" of electrical discharge.
Mixtures: Telom-X-geneSynonyms: potassium(I) cation, potassium(1+)Human C1-esterase inhibitor
go.drugbank.com/drugs/DB06404ApprovedInvestigational[L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a human genetic disorder caused by a shortage of C1 inhibitor activity that results in an overreaction … C1 Esterase Inhibitor (Human) is composed of purified endogenous complement component-1 esterase inhibitor (hC1INH) isolated from human plasma.
Products: CİNRYZE 500 IU/5 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 2 ADETAvapritinib
go.drugbank.com/drugs/DB15233ApprovedInvestigational[A189339,L40363] It is one of the first medications available for the treatment of multidrug resistant cancers.[A189327] Avapritinib shares a similar mechanism with [ripretinib]. … Avapritinib, or BLU-285,[A189327] is a selective tyrosine kinase inhibitor of KIT and platelet derived growth factor receptor alpha indicated for the treatment of unresectable, metastatic gastrointestinal
Categories: MATE 2-K Inhibitors, MATE 1 InhibitorsTeplizumab
go.drugbank.com/drugs/DB06606ApprovedInvestigationalTeplizumab (teplizumab-mzwv) is a humanized IgG1 kappa CD3-directed monoclonal antibody used to delay the onset of type 1 diabetes (T1D). … [A241480,A241045,A241475,L44091] T1D is an autoimmune condition in which T cell-mediated destruction of pancreatic β cells leads to loss of insulin production, impaired glycemic control, and reliance on
Glycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approved[L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and is considered to have a wider therapeutic window than [tiotropium]. … Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers.[L33110] They are both quaternary ammonium compounds and long acting muscarinic antagonists.
Mixtures: TRİMBOW 87/5/9 MCG AEROSOL İNHALASYON ÇÖZELTİSİ, 120 DOZ, TRYDONİS 87 MCG/5 MCG/9 MCG AEROSOL İNHALASYONU, ÇÖZELTİ, 120 DOZCategories: MATE 1 Substrates, Cytochrome P-450 SubstratesTecovirimat
go.drugbank.com/drugs/DB12020ApprovedInvestigationalHowever, there have been longstanding concerns that smallpox may be used as a bioweapon.[A35133,L3614] Tecovirimat is an antiviral drug that was identified via a high-throughput screen in 2002. … The World Health Organization declared smallpox, a contagious and sometimes fatal infectious disease, eradicated in 1980.
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP3A InducersSynonyms: ST-246Gastric intrinsic factor
go.drugbank.com/drugs/DB09349ApprovedIntrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach that is necessary for the absorption of vitamin B12 (cobalamin) later … Intrinsic factor is not currently available in any FDA or Health Canada approved products.
Ofatumumab
go.drugbank.com/drugs/DB06650ApprovedInvestigationalOfatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. … It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology.
Products: İNFÜZYONLUK ÇÖZELTİ KONSATRESİ İÇEREN FLAKON (3 ADET), İNFÜZYONLUK ÇÖZELTİ KONSATRESİ İÇEREN FLAKON (1 ADET)