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Displaying results 1651 - 1660 of 10000 in total
  1. Drug

    Malacidin B

    go.drugbank.com/drugs/DB14052
    Experimental

    Malacidin B, along with [DB14051], is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria [A33312]. … While structurally similar to other macrocycle drugs like [DB00080] and [DB06087], Malacidin B appears to act via its own distinct mechanism.

    Synonyms: Malacidin B
  2. Drug

    (S)-Warfarin

    go.drugbank.com/drugs/DB14055
    Investigational

    S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A7166] … Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways.

    Categories: Vitamin K Antagonists, Cytochrome P-450 SubstratesSynonyms: (S)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone, 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-chromen-2-one
  3. Drug

    SC-236

    go.drugbank.com/drugs/DB14059
    Experimental

    SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) [L2964] that has been studied in cancer therapy [A33375], lower back pain [A33376], and inflammation [A33373], [A33374

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Dexverapamil

    go.drugbank.com/drugs/DB14063
    Experimental

    Synonyms: (R)-verapamil, (+)-(R)-verapamilCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  5. Drug

    Emopamil

    go.drugbank.com/drugs/DB14064
    Experimental

    Prevents renal injury after warm & cold ischemia.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  6. Drug

    Lomerizine

    go.drugbank.com/drugs/DB14065
    Experimental

    Lomerizine is a diphenylmethylpiperazine calcium channel blocker[A245378, A245383] with relatively selective central nervous system (CNS) effects.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  7. Drug

    Dexniguldipine

    go.drugbank.com/drugs/DB14068
    Experimental

    Synonyms: (R)-niguldipineCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  8. Drug

    ONT-093

    go.drugbank.com/drugs/DB14069
    Experimental

    ONT-093 is an orally bioavailable inhibitor of P-glycoprotein (P-gp). … In pre-clinical studies, ONT-093 could inhibit P-gp and reverse multidrug resistance at nM concentrations with no effect on paclitaxel pharmacokinetics.

    Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 1-Ring
  9. Drug

    Morrhuic acid

    go.drugbank.com/drugs/DB14087
    Investigational

    Morrhuic acid is a mixture of unsaturated fatty acids obtained from cod liver oil.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Dimethyl sulfone

    go.drugbank.com/drugs/DB14090
    Investigational

    Mixtures: GLUCONITRIN F®, GLUCONITRIN F®Products: Live-well™ OsteMSM 500 Tablet, Live-well™ OsteMSM 1000 Tablet