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Ajmaline
go.drugbank.com/drugs/DB01426ApprovedWithdrawnIt has also been used for many years as a drug to challenge the conduction system of the heart in cases of bundle branch block and syncope. … An alkaloid found in the root of Rauwolfia serpentina, among other plant sources.
Synonyms: (5aR,6S,8S,10S,11S,11aS,12aR,13R)-5-methyl-5a,6,8,9,10,11,11a,12-octahydro-5H-6,10:11,12a-dimethanoindolo[3,2-b]quinolizine-8,13-diolCategories: Heterocyclic Compounds, 2-RingFidaxomicin
go.drugbank.com/drugs/DB08874ApprovedInvestigational[A190501] Because fidaxomicin contains an 18-membered lactone ring in its structure, it is referred to as a macrocyclic lactone antibiotic drug. … [A7445] It mediates its potent bactericidal action on the bacteria by inhibiting the bacterial RNA synthase, thereby disrupting bacterial transcription.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: DİFİCLİR 200 MG FİLM KAPLI TABLET, 20 ADETMethohexital
go.drugbank.com/drugs/DB00474ApprovedAn intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Synonyms: 5-Allyl-5-(3-hexyn-2-yl)-1-methylbarbituric acid, (±)-5-allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric acidProducts: Brietal 500 mg - TrockenstechampullePeppermint oil
go.drugbank.com/drugs/DB11198ApprovedInvestigationalIt is also an active ingredient in topical analgesics for the relief of joint and muscle pain. Peppermint oil can be applied topically to temporarily relieve tension-type headache. … Peppermint oil is safe and well-tolerated at commonly recommended dosage [A33055].
Mixtures: MENTOSEPTOL GARGARA, 100 ML, BUĞUMENTOL BUĞU, 40 GCategories: Herbs and Natural Products, Cytochrome P-450 CYP1A2 InhibitorsTuroctocog alfa
go.drugbank.com/drugs/DB09109ApprovedTuroctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally … [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104]
Products: โนโวเอท 500 หน่วยสากล, NOVOEIGHT®1000 UI POLVO Y SOLVENTE PARA SOLUCIÓN INYECTABLEEnfuvirtide
go.drugbank.com/drugs/DB00109ApprovedInvestigationalThe first agent in the novel class of antiretroviral drugs called HIV fusion inhibitors, enfuvirtide works by inhibiting HIV-1 fusion with CD4 cells.
Categories: Gene Products, env, env Gene Products, Human Immunodeficiency VirusProducts: FUZEON POLVO SOLUCION INYECTABLE 90 MG/MIGadoteridol
go.drugbank.com/drugs/DB00597ApprovedInvestigational[A263076] Initially approved by the FDA in 1992, gadoteridol received additional approval in 2020 for use in pediatric patients less than 2 years old.[L49876] … gadolinium in the brain.
Synonyms: gadolinium 2,2',2''-[10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl]triacetateCategories: Compounds used in a research, industrial, or household settingNitric Oxide
go.drugbank.com/drugs/DB00435ApprovedInvestigationalIt reacts with the ozone in air to form nitrogen dioxide, signalled by the appearance of the reddish-brown color. … It is also a toxic air pollutant produced by automobile engines and power plants.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP1A2 InhibitorsProducts: Noxivent 101, Noxivent 102Perflutren
go.drugbank.com/drugs/DB00556ApprovedInvestigationalThe difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image. … During echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.
Categories: Compounds used in a research, industrial, or household settingProducts: CIPROFLOXACINO TABLETAS X 500 MG, Definity RTIxazomib
go.drugbank.com/drugs/DB09570ApprovedInvestigational[A264329] Ixazomib was approved by the FDA on November 20, 2015, making it the first oral proteasome inhibitor approved in the US. … [A264319] It was later approved by Health Canada on August 3, 2016,[L51239] and by the EMA on November 21, 2016.
Synonyms: 2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-5-oxo-1,3,2-dioxaborolane-4,4-diacetic acid, BORONIC ACID, B-((1R)-1-((2-((2,5-DICHLOROBENZOYL)AMINO)ACETYL)AMINO)-3-METHYLBUTYL)-Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates