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Pafolacianine
go.drugbank.com/drugs/DB15413ApprovedInvestigational[A242572] On November 29, 2021, the FDA approved pafolacianine as an adjunct imaging agent for intraoperative identification of malignant lesions in adult patients with ovarian cancer. … Pafolacianine targets the folate receptor alpha (FRα) which is upregulated in numerous epithelial malignancies.
Categories: Compounds used in a research, industrial, or household settingSpinosad
go.drugbank.com/drugs/DB08823ApprovedVet approvedSpinosad is an insecticide based on a compound found in S. spinosa, a bacterial species. … Spinosad is a pediculicide mixture of spinosyn A and spinosyn D (in an approximately 5:1 ratio, respectively) used in the topical treatment of head lice in children (four years old and older) and in adults
Categories: Compounds used in a research, industrial, or household settingDobutamine
go.drugbank.com/drugs/DB00841ApprovedInvestigationalA beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Mixtures: Dobutamine Hydrochloride in DextroseCategories: Compounds used in a research, industrial, or household settingEteplirsen
go.drugbank.com/drugs/DB06014ApprovedInvestigational[A244930] It is caused by loss-of-function mutations in the DMD gene coding for dystrophin, an essential protein involved in maintaining the structural integrity and function of muscle fibres. … Eteplirsen was first approved by the FDA in September 2016 for the treatment of Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation of the DMD gene, which codes for dystrophin, that
Synonyms: N-dimethylphosphonamidate) RNA, dimethylamino)](2',3'-dideoxy-2',3'-imino-2',3'-seco)(2'a→5')(C-m5U-C-C-A-A-C-A-m5U-C-A-A-G-G-A-A-G-A-m5U-G-G-C-A-m5U-m5U-m5U-C-m5U-A-G),5'-(P-(4-((2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)carbonyl)-1-piperazinyl)-N,Categories: Compounds used in a research, industrial, or household settingGallium Ga-68 gozetotide
go.drugbank.com/drugs/DB16019ApprovedInvestigationalpositive lesions in men with prostate cancer. … [L43542] In December of the same year, the drug was fully authorized by the EMA.[L44682] In Octer 2022, Ga-68 PSMA-11 was approved by Health Canada for diagnostic use in men with prostate cancer.
Categories: Compounds used in a research, industrial, or household settingSodium feredetate
go.drugbank.com/drugs/DB13381ApprovedMixtures: Cavan-EC SOD DHA, Cavan-EC SOD DHACategories: Compounds used in a research, industrial, or household settingCalcium ascorbate
go.drugbank.com/drugs/DB14483ApprovedNutraceuticalMixtures: Longevit-E - Capsule, Supplements De Vitamines Et MinerauxCategories: Compounds used in a research, industrial, or household settingCalaspargase pegol
go.drugbank.com/drugs/DB14730ApprovedInvestigationalAsparagine is incorporated into most proteins, and the synthesis of proteins is stopped when asparagine is absent, which inhibits RNA and DNA synthesis, resulting in a halt in cellular proliferation. … Asparaginase is an important agent used to treat acute lymphoblastic leukemia (ALL) [A40270].
Categories: Compounds used in a research, industrial, or household settingSpirapril
go.drugbank.com/drugs/DB01348ApprovedInvestigationalACE inhibitors are used primarily in treatment of hypertension and congestive heart failure. … Spirapril is an ACE inhibitor antihypertensive drug used to treat hypertension. Spirapril is converted to the active spiraprilat after administration.
Categories: Agents Acting on the Renin-Angiotensin SystemSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
go.drugbank.com/bio_entities/BE0002254TargetHumansIron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed
Synonyms: Iron-sulfur subunit of complex II