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Leuprolide
go.drugbank.com/drugs/DB00007ApprovedInvestigationalLeuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). … [A203126, A203132] Leuprolide was first approved in 1985 as a daily subcutaneous injection under the tradename Lupron™ by Abbvie Endocrine Inc.
International brands: Prostap SR, Prostap 3Products: LUCRIN DEPOT-3 M 11,25 IM/SC ENJEKSIYONLUK FLAKON, 1 ADET, LUCRIN DEPOT-3,75 MG IM/SC ENJEKSIYONLUK FLAKON, 1 ADETUrokinase
go.drugbank.com/drugs/DB00013ApprovedInvestigationalWithdrawnUrokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase. … [A191943] Urokinase remains connected between these 2 chains by a sulfhydryl bond.[A191943] Urokinase was granted FDA approval on 16 January 1978.[L12138]
Products: UROKINASE KGCC INJ. 250000 IU FLAKON, 1 ADET, UROKINASE KGCC INJ. 500000 IU FLAKON, 1 ADETPeginterferon alfa-2b
go.drugbank.com/drugs/DB00022ApprovedInvestigationalPeginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). … Peginterferon alfa-2b is available as a variable dose injectable product (tradename Pegintron) used for the treatment of chronic Hepatitis C.
Categories: Hepatitis C, Interferon Type ISynonyms: PEG-IFN-α-2b, Pegylated Interferon α-2bThyrotropin alfa
go.drugbank.com/drugs/DB00024ApprovedInvestigationalVet approvedIt is a heterodimeric glycoprotein comprised of two non-covalently linked subunits, an alpha subunit of 92 amino acid residues containing two N-linked glycosylation sites and a beta subunit of 112 residues … containing one N-linked glycosylation site.
Products: THYROGEN®, THYROGEN(R)Anakinra
go.drugbank.com/drugs/DB00026ApprovedInvestigationalAnakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist (IL-1Ra) composed of 153 amino acid residues. … This drug binds to the IL-1 receptor, competing with and inhibiting the activity of IL-1 alpha and beta.
Categories: Interleukin-1 Receptor AntagonistSynonyms: Interleukin-1 receptor antagonist anakinraAldesleukin
go.drugbank.com/drugs/DB00041ApprovedInvestigationalThis recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon … Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene.
Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 CYP3A InhibitorsSynonyms: 125-L-Serine-2-133-interleukin 2, 125-L-serine-2-133-interleukin 2 (human reduced)Botulinum toxin type B
go.drugbank.com/drugs/DB00042ApprovedNeurotoxin produced by fermentation of clostridium botulinum type B. The protein exists in noncovalent association with hemagglutinin and nonhemagglutinin proteins as a neurotoxin complex. … The neurotoxin complex is recovered from the fermentation process and purified through a series of precipitation and chromatography steps.
Synonyms: BTX-B, Botulin BLutropin alfa
go.drugbank.com/drugs/DB00044ApprovedInvestigationalLutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units.
Mixtures: PERGOVERIS 150 IU/75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET, PERGOVERIS 150 IU/75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 3 ADETProducts: LUVERIS 75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADETSomatotropin
go.drugbank.com/drugs/DB00052ApprovedInvestigationalHuman growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. … [A228188] Recombinant growth hormone is available as a subcutaneous injection for children and adults under a wide variety of brand names.
Mixtures: Nutropin - Kit Pws(5mg) & Liq(10ml) Im Sc, Nutropin - Kit Pws(10mg) & Liq(10ml) Im ScCategories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 InducersImiglucerase
go.drugbank.com/drugs/DB00053ApprovedInvestigationalHuman Beta-glucocerebrosidase or Beta-D-glucosyl-N-acylsphingosine glucohydrolase E.C. 3.2.1.45. 497 residue protein with N-linked carbohydrates, MW=59.3 kD. … The modification alters the sugar residues at the non-reducing ends of the oligosaccharide chains of the glycoprotein so that they are predominantly terminated with mannose residues.
Products: CEREZYME 200 U INFUZYONLUK KONSANTRE ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 1 ADET, CEREZYME 400 U/10 ML İNFÜZYONLUK KONSANTRE ÇÖZELTİ İÇİN TOZ