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Displaying results 1671 - 1680 of 10000 in total
  1. Indication

    Equinus Foot Deformity in Children With Cerebral Palsy

    go.drugbank.com/conditions/DBCOND0085039
    Drugs: Clostridium botulinum
    Synonyms: Equinus Foot Deformity in Children With Cerebral Palsy
  2. Indication

    Uncomplicated veins <1 mm in diameter Spider Veins

    go.drugbank.com/conditions/DBCOND0080571
    Drugs: Polidocanol
    Synonyms: Uncomplicated veins <1 mm in diameter Spider Veins, Uncomplicated veins <1 mm in diameter Spider vein
  3. Drug

    Pomalidomide

    go.drugbank.com/drugs/DB08910
    ApprovedInvestigational

    Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.

    Categories: Antineoplastic and Immunomodulating AgentsProducts: POMALYST® 2MG, POMALYST CAPSULE 2MG
  4. Drug

    Brexpiprazole

    go.drugbank.com/drugs/DB09128
    ApprovedInvestigational

    Brexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called serotonin-dopamine activity modulator (SDAM). … It also displays stronger antagonism at the 5-HT1A and 5-HT2A receptors.[A182186, A38385, A259661] Brexpiprazole was first approved by the FDA on July 10, 2015.

    Products: Rexulti 2mg film-coated tablets, REXULTI FILM-COATED TABLETS 2MG
  5. Target

    Cocaine- and amphetamine-regulated transcript protein

    go.drugbank.com/bio_entities/BE0000867
    TargetHumans

    It promotes neuronal development and survival in vitro … by neuropeptide Y and regulated by leptin in the hypothalamus.

    Polypeptides: Cocaine- and amphetamine-regulated transcript protein
  6. Target

    Multidrug and toxin extrusion protein 1

    go.drugbank.com/bio_entities/BE0003657
    TransporterEnzymeTargetHumans

    Plays a physiological role in the excretion of cationic compounds including endogenous metabolites, drugs, toxins through the kidney and liver, into urine and bile respectively (PubMed:16330770, PubMed … May also contribute to regulate the transport of cationic compounds in testis across the blood-testis-barrier (Probable)

    Polypeptides: Multidrug and toxin extrusion protein 1
  7. Target

    Sodium- and chloride-dependent betaine transporter

    go.drugbank.com/bio_entities/BE0004777
    TargetTransporterHumans

    Transporter that mediates cellular uptake of betaine and GABA in a sodium- and chloride-dependent process (PubMed:7589472). … Probably also involved in renal and hepatic osmotic regulation (By similarity)

    Polypeptides: Sodium- and chloride-dependent betaine transporter
  8. Target

    Hyaluronan and proteoglycan link protein 1

    go.drugbank.com/bio_entities/BE0004933
    TargetHumans

    Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix

    Polypeptides: Hyaluronan and proteoglycan link protein 1
  9. Target

    Hyaluronan and proteoglycan link protein 3

    go.drugbank.com/bio_entities/BE0004935
    TargetHumans

    May function in hyaluronic acid binding

    Polypeptides: Hyaluronan and proteoglycan link protein 3
  10. Target

    Calcium and integrin-binding protein 1

    go.drugbank.com/bio_entities/BE0008691
    TargetHumans

    Forms a complex with TMC6/EVER1 and TMC8/EVER2 in lymphocytes and keratynocytes where CIB1 stabilizes TMC6 and TMC8 levels and reciprocally (PubMed:30068544, PubMed:32917726) … Participates in the endomitotic cell cycle of megakaryocyte, a form of mitosis in which both karyokinesis and cytokinesis are interrupted.

    Polypeptides: Calcium and integrin-binding protein 1Synonyms: Calcium- and integrin-binding protein