Search

Displaying results 1681 - 1690 of 10000 in total
  1. Drug

    Tetracaine

    go.drugbank.com/drugs/DB09085
    ApprovedInvestigationalVet approved

    Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.

    Mixtures: Lidocaine 7% / Tetracaine 7%, Ndc 72934- 5010-4 Benzocaine 20% / Lidocaine 8% / Tetracaine 4%.Categories: Esters of Aminobenzoic Acid, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use
  2. Target

    Linear primary-alkylsulfatase

    go.drugbank.com/bio_entities/BE0003744
    TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

    In addition, contributes to the in vivo virulence of P.aeruginosa by playing a central role in the degradation of mucin, a glycoprotein that is the primary component of the mucus overlaying the host epithelial … Plays a role in the degradation of both protein and carbohydrate moieties in mucin via the release of sulfate from mucin, D-galactose 6-sulfate (Gal-6S) and N-acetyl-D-glucosamine 6-sulfate (GlcNAc-6S)

    Polypeptides: Linear primary-alkylsulfataseSynonyms: Type III linear primary-alkylsulfatase
  3. Target

    Macrophage receptor MARCO

    go.drugbank.com/bio_entities/BE0009001
    TargetHumans

    Also plays a role in binding of unopsonized particles by alveolar macrophages (By similarity). Binds to the secretoglobin SCGB3A2 (PubMed:12847263)

    Polypeptides: Macrophage receptor MARCO
  4. Drug

    Galantamine

    go.drugbank.com/drugs/DB00674
    ApprovedInvestigational

    , cognitive impairment in schizophrenia and bipolar disorder, and autism; however, re-development of the drug for Alzheimer’s disease did not commence until the early 1990s due to difficulties in extraction … Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: REMINYL ®ER CAPSULAS DE 8 MG, REMINYL® SOLUCION ORAL DE 4 MG/ML
  5. Drug

    Histamine

    go.drugbank.com/drugs/DB05381
    ApprovedInvestigational

    It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. … A depressor amine derived by enzymatic decarboxylation of histidine.

    Mixtures: DR. MIKES Ponos Pain Relief Cream Roll-On, Histamine DHCl 0.10 Percent and Menthol 2 PercentCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP3A Inhibitors
  6. Indication

    Oligospermia

    go.drugbank.com/conditions/DBCOND0001337
    Drugs: Mesterolone
    Synonyms: Decline in sperm count
  7. Drug

    Trastuzumab

    go.drugbank.com/drugs/DB00072
    ApprovedInvestigational

    [L14015] It is used as a treatment of human epidermal growth factor receptor (HER)-2+ metastatic breast cancer, where there is a proven amplification of the HER-2 oncogene or over-expression of the HER … -2 protein in tumours.

    Mixtures: PHESGO® 600MG/600MG, PHESGO® 600MG/600MGCategories: HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors
  8. Indication

    Neck Pain

    go.drugbank.com/conditions/DBCOND0003823
    Drugs: Eperisone · Escin
    Synonyms: Cervicalgia - pain in neck, Nonspecific pain in the neck region
  9. Indication

    Leg cramps

    go.drugbank.com/conditions/DBCOND0093960
    Drugs: Diltiazem
    Synonyms: Cramps in legs, Muscle cramps in leg
  10. Indication

    Skin chapped

    go.drugbank.com/conditions/DBCOND0097499
    Drugs: Dimethicone 410 · Triamcinolone
    Synonyms: Splits in skin, Cracks in skin