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Displaying results 1681 - 1690 of 10000 in total
  1. Drug

    Lumacaftor

    go.drugbank.com/drugs/DB09280
    ApprovedInvestigational

    Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, a transmembrane ion … [A20343] Improvements in lung function (ppFEV1) were found to be statistically significant, but minimal, with only a 2.6-3.0% change from baseline with more than 70% of patients failing to achieve an absolute

  2. Drug

    Sucrose

    go.drugbank.com/drugs/DB02772
    ApprovedInvestigational

    It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a food and a sweetener. … A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons.

    Mixtures: Childrens Emetrol Dye Free GrapeCategories: Diet, Food, and Nutrition, Compounds used in a research, industrial, or household setting
  3. Drug

    Semaglutide

    go.drugbank.com/drugs/DB13928
    ApprovedInvestigational

    as the first approved drug for such use since 2014. … Semaglutide is a glucagon-like peptide 1 (GLP-1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity.

    Products: RYBELSUS 3 MG TABLET, 30 ADET, RYBELSUS 3 MG TABLET, 60 ADET
  4. Drug

    Atosiban

    go.drugbank.com/drugs/DB09059
    ApprovedInvestigational

    Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used intravenously to halt premature labor. … Although initial studies suggested it could be used as a nasal spray and hence would not require hospital admission, it is not used in that form.

    Products: ATOSIBAN SUN, Atosiban Sun
  5. Indication

    Tic Disorder, Combined Vocal and Multiple Motor

    go.drugbank.com/conditions/DBCOND0082267
    Drugs: Clonazepam · Clonidine · Fluphenazine · Guanfacine · Haloperidol · Olanzapine +1 more
    Synonyms: Gilles de la Tourette, Gilles de la Tourette's
  6. Drug

    Tivantinib

    go.drugbank.com/drugs/DB12200
    Investigational

    Tivantinib has been investigated in Solid Tumors.

    Categories: Proto-Oncogene Proteins c-met, antagonists & inhibitors
  7. Drug

    Lamivudine

    go.drugbank.com/drugs/DB00709
    ApprovedInvestigational

    A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring.

    Mixtures: N/A, N/ACategories: Antivirals used in combination for the treatment of HIV infections, Medications that reduce magnesium levels
  8. Drug

    Chlorobutanol

    go.drugbank.com/drugs/DB11386
    ApprovedVet approvedWithdrawn

    Chlorobutanol, or chlorbutol, is an alcohol-based preservative with no surfactant activity [A32746]. … Chlorobutanol is a common detergent preservative in eye drops and other ophthalmic therapeutic formulations [A32744].

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    Fedratinib

    go.drugbank.com/drugs/DB12500
    ApprovedInvestigational

    [A183176,L8090] It is an anilinopyrimidine derivative.[A183188] Fedratinib was granted FDA approval on August 16, 2019.[L8090] … Fedratinib, also known as SAR302503 and TG101348, is a tyrosine kinase inhibitor used to treat intermediate-2 and high risk primary and secondary myelofibrosis.

    Categories: combinations of sulfonamidesProducts: Inrebic 100 mg Sert Kapsül, 120 ADET
  10. Drug

    Somatrem

    go.drugbank.com/drugs/DB09098
    ApprovedWithdrawn

    these hormone agents have been proven effective at increasing the height of children with or without growth hormone deficiency [A32292]. … Such discussion revolves around whether patients' natural disposition of short stature should be considered a medical condition justifying medical treatment with such hormone therapy - especially when