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Displaying results 1681 - 1690 of 10000 in total
  1. Drug

    Ulipristal

    go.drugbank.com/drugs/DB08867
    ApprovedInvestigational

    Ulipristal is currently recommended as first line therapy for emergency contraception, due to improved efficacy and similar side effect profile as compared to the traditional use of levonorgestrel or the … It is a derivative of 19-norprogesterone and has both antagonistic and partial agonist activity at the progesterone receptor.

    Products: JOSEİ 30 MG TABLET, 1 ADET, Nextelle 30 mg Tablet, 1 ADET
  2. Drug

    Dosulepin

    go.drugbank.com/drugs/DB09167
    ApprovedInvestigational

    Its hydrochloride form is a common active ingredient in different drug formulations. … It is not FDA-approved due to low therpeutic index and significant toxicity in overdose.

    Synonyms: (3E)-3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine, 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo(b,e)thiepinProducts: ESPIN CAPSULE 25 mg
  3. Drug

    Amino acids

    go.drugbank.com/drugs/DB09393
    Investigational

    Mixture of amino acids ; used for parenteral nutrition in infants.

    Mixtures: Clinimix 3 % G-E - Infusionsbeutel, Clinimix 5 % G-E - InfusionsbeutelProducts: AMINOVENOS-N PED % 10 İNTRAVENÖZ İNFÜZYON SOLÜSYONU, 250 ML, AMINOVENOS-N PED % 10 İNTRAVENÖZ İNFÜZYON SOLÜSYONU, 100 ML
  4. Drug

    Polyvinyl alcohol

    go.drugbank.com/drugs/DB11060
    Approved

    It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing. … Polyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes [L2826].

    Mixtures: SICCAPROTECT 10 ML GOZ DAMLASI, FULLFRESH 5,60 MG/2,40 MG TEK DOZLUK GÖZ DAMLASI, ÇÖZELTİCategories: Compounds used in a research, industrial, or household setting
  5. Drug

    Penciclovir

    go.drugbank.com/drugs/DB00299
    Approved

    Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.

    Synonyms: 9-[2-hydroxy-1-(hydroxymethyl)-ethoxymethyl]guanine, 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanineCategories: Heterocyclic Compounds, 2-Ring
  6. Drug

    Sebelipase alfa

    go.drugbank.com/drugs/DB11563
    ApprovedInvestigational

    This lipid accumulation can lead to end-organ damage in the form of liver dysfunction or malabsorption secondary to intestinal dysfunction. … The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism of lipids, and its absence or deficiency results in the accumulation of lipids in various organs

    Synonyms: SBC-102Products: KANUMA® 2 MG/ML CONCENTRADO PARA SOLUCION PARA INFUSION.
  7. Drug

    Nonoxynol-9

    go.drugbank.com/drugs/DB06804
    ApprovedWithdrawn

    N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants. … It is the most commonly used spermicidal contraceptive in the UK and the USA. In several European countries, spermicides are no longer on the market.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: 26-(Nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol
  8. Drug

    Teniposide

    go.drugbank.com/drugs/DB00444
    ApprovedInvestigational

    Accumulated breaks in DNA prevent cells from entering into the mitotic phase of the cell cycle, and lead to cell death. Teniposide acts primarily in the G2 and S phases of the cycle. … This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding.

    Synonyms: 4'-demethylepipodophyllotoxin 9-(4,6-O-(R)-2-thenylidene-beta-D-glucopyranoside)Products: VUMON VM 26 INYECTABLE X 50 MG / 5ML
  9. Target

    Sodium channel protein type 10 subunit alpha

    go.drugbank.com/bio_entities/BE0000177
    TargetHumans

    Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sod...

    Polypeptides: Sodium channel protein type 10 subunit alpha
  10. Target

    ATP-sensitive inward rectifier potassium channel 10

    go.drugbank.com/bio_entities/BE0009591
    TargetHumans

    May be responsible for potassium buffering action of glial cells in the brain (By similarity). Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it (Pu...

    Polypeptides: ATP-sensitive inward rectifier potassium channel 10Synonyms: Potassium channel, inwardly rectifying subfamily J member 10