ATP-sensitive inward rectifier potassium channel 10

BE0009591ProteinHumansKCNJ10

May be responsible for potassium buffering action of glial cells in the brain (By similarity). It is acted on by 10 drugs in DrugBank.

Gene name
KCNJ10
UniProtKB entry
P78508Swiss-Prot
Cellular location
Membrane
Residues / weight
379 residues · 42,508 Da
Also known as
ATP-dependent inwardly rectifying potassium channel Kir4.1 · Inward rectifier K(+) channel Kir1.2 · Potassium channel, inwardly rectifying subfamily J member 10

Resolves to

Protein
UniProtP78508UniProt nameKCJ10_HUMAN
Gene
HGNCHGNC:6256NCBI Gene3766GeneCardsKCNJ10
Pharmacology
IUPHAR/GtoPdb438KEGGhsa:3766
Drugs

What you can answer from here — as of September 03, 2024

10DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which approved drugs act on ATP-sensitive inward rectifier potassium channel 10, how selective are they, and which programs against it are still in active trials?

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