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Displaying results 161 - 170 of 367 in total
  1. Target

    Protein S100-G

    go.drugbank.com/bio_entities/BE0004083
    TargetCarrierHumans

    Synonyms: S100 calcium-binding protein G, Vitamin D-dependent calcium-binding protein, intestinalFunction: calcium ion binding
  2. Target

    Transient receptor potential cation channel subfamily V member 5

    go.drugbank.com/bio_entities/BE0005112
    TransporterHumans

    The channel is activated by low internal calcium level and the current exhibits an inward rectification (PubMed:11549322, PubMed:18768590). … Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine (PubMed:11549322, PubMed:18768590).

    Synonyms: Calcium transport protein 2, Epithelial calcium channel 1Function: calcium channel activity
  3. Target

    Sulfite oxidase, mitochondrial

    go.drugbank.com/bio_entities/BE0002927
    TargetEnzymeHumans

    Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids (By similarity). … Can run in reverse direction and reduce nitrite to nitric oxide under physiologically relevant conditions, such as hypoxia (PubMed:41337830)

    Polypeptides: Sulfite oxidase, mitochondrial
  4. Target

    Acetyl-coenzyme A synthetase 2-like, mitochondrial

    go.drugbank.com/bio_entities/BE0000746
    TargetHumans

    Acetate is the preferred substrate (PubMed:16788062). Can also utilize propionate with a much lower affinity (By similarity). … Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient (By similarity)

    Synonyms: Acetate--CoA ligase 2
  5. Target

    Linear primary-alkylsulfatase

    go.drugbank.com/bio_entities/BE0003744
    TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

    Acts in vitro on primary alkylsulfates such as decyl sulfate, octyl sulfate and hexyl sulfate, but not on sulfated sugars and arylsulfates (PubMed:16684886, PubMed:23061549). … Plays a role in the degradation of both protein and carbohydrate moieties in mucin via the release of sulfate from mucin, D-galactose 6-sulfate (Gal-6S) and N-acetyl-D-glucosamine 6-sulfate (GlcNAc-6S)

    Synonyms: Sodium dodecyl sulfate hydrolase
  6. Target

    Sulfide dehydrogenase

    go.drugbank.com/bio_entities/BE0002870
    TargetWolinella succinogenes

    Polypeptides: Sulfide dehydrogenaseSynonyms: Sulfide dehydrogenase precursor
  7. Target

    Human Carboxylesterases

    go.drugbank.com/bio_entities/BE0010086
    EnzymeTargetHumans

    Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine (PubMed:9169443). … Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (PubMed:9169443).

    Synonyms: Methylumbelliferyl-acetate deacetylase 2, Methylumbelliferyl-acetate deacetylase 1
  8. Target

    Protein S100-A2

    go.drugbank.com/bio_entities/BE0003602
    TargetHumans

    May function as calcium sensor and modulator, contributing to cellular calcium signaling. … May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. May also play a role in suppressing tumor cell growth

    Synonyms: S100 calcium-binding protein A2Function: calcium ion binding
  9. Target

    Peripheral plasma membrane protein CASK

    go.drugbank.com/bio_entities/BE0002641
    TargetHumans

    Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. … May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.

    Synonyms: Calcium/calmodulin-dependent serine protein kinase
  10. Target

    Calbindin

    go.drugbank.com/bio_entities/BE0008690
    CarrierHumans

    Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase

    Synonyms: Vitamin D-dependent calcium-binding protein, avian-typeFunction: calcium ion binding