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Benzatropine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126985Drug actionBenzatropine binds to the sodium-dependent dopamine transporter which prevents dopamine from re-entering the presynaptic neuron.
Enzymes: Sodium-dependent dopamine transporterBenzphetamine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126989Drug actionBenzphetamine binds to the sodium-dependent dopamine transporter, preventing dopamine from re-entering the presynaptic neuron.
Enzymes: Sodium-dependent dopamine transporterVanoxerine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126997Drug actionVanoxerine binds to the sodium-dependent dopamine transporter, preventing dopamine from re-entering the presynaptic neuron.
Enzymes: Sodium-dependent dopamine transporterPergolide Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126635Drug actionThe dopamine D2 receptor is a 7-transmembrane G-protein coupled receptor associated with Gi proteins. In lactotrophs, stimulation of dopamine D2 receptor causes inhibition of adenylyl cyclase, which decreases intracellular cAMP concentra...
Enzymes: Sodium-dependent dopamine transporterAsenapine Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126736Drug actionAsenapine is a serotonin, dopamine, noradrenaline, and histamine antagonist in which asenapine possess more potent activity with serotonin receptors than dopamine. Asenapine is an atypical antipsychotic multireceptor neuroleptic drug whi...
Enzymes: Sodium-dependent dopamine transporterCocaine Dopamine-reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126543Drug actionCocaine is a local anesthesia and vasoconstrictor that is clinically used during diagnostic proceedures or during surgery in or through the nasal cavity. It comes in drugs called Goprelto and Numbrino which comes as a nasal spray. In the...
Enzymes: Sodium-dependent dopamine transporterDihydroergocryptine Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126659Drug actionAlpha-dihydroergocryptine is usually referred to the mixture of the alpha and beta dihydroergocryptine. These two compounds are differentiated in the position of a methyl group. This structural difference is due to a proteinogenic amino ...
Enzymes: Sodium-dependent dopamine transporterErgoloid mesylate Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126658Drug actionErgoloid Mesylate is an equiproportional preparation of three different ergotamantriones: dihydroergocornine, dihydroergocristine, and dihydroergocryptine. All these components are produced by the fungus Claviceps purpurea and are all de...
Enzymes: Sodium-dependent dopamine transporterApomorphine Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126633Drug actionApomorphine is a non-ergoline dopamine agonist with high binding affinity to dopamine D2, D3, and D5 receptors. Stimulation of D2 receptors in the caudate-putamen, a region of the brain responsible for locomotor control, may be responsib...
Enzymes: Sodium-dependent dopamine transporterEpicriptine Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126655Drug actionEpicriptine effect is mainly due to the agonistic activity on dopamine receptor. Epicriptine is also known as beta-dihydroergocryptine presents a molecular formula of 9,10 alpha-dihydro-13'-epi-b-ergocryptine. Together with the alpha-dih...
Enzymes: Sodium-dependent dopamine transporter