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Atropine
go.drugbank.com/drugs/DB00572ApprovedInvestigationalVet approvedAtropine is an alkaloid originally synthesized from Atropa belladonna. It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active. … [A251660] Atropine is a relatively inexpensive drug and is included in the World Health Organization List of Essential Medicines.[A251675]
Synonyms: dl-Hyoscyamine, dl-tropyltropateMixtures: PHARMANIAGA DIPHENOXYLATE A TABLETThe Oncogenic Action of L-2-Hydroxyglutarate in Hydroxyglutaric aciduria
smpdb.ca/view/SMP0002358DiseaseThis results in modulations of HIF-mediated hypoxia responses and alterations in gene expression through global epigenetic remodelling that may contribute to malignant transformation. … L-2-hydroxyglutarate is a competitive inhibitor of 2OG-dependent dioxygenases resulting in genetic changes and malignancies.
Midazolam
go.drugbank.com/drugs/DB00683ApprovedIllicitInvestigational[A257153] Midazolam is considered a schedule IV drug in the United States due to the low potential for abuse and low risk of dependence.[L5074] … [A173842] It belongs to a class of drugs called _benzodiazepines_. This drug is unique from others in this class due to its rapid onset of effects and short duration of action.
Products: N/a, Midazolam in Sodium ChlorideLeucovorin
go.drugbank.com/drugs/DB00650ApprovedInvestigationalLeucovorin, also known as folinic acid or citrovorum factor, is a reduced form of folic acid that serves as a vital coenzyme in nucleic acid synthesis. … [L56091, L56092] Historically developed in 1945, leucovorin has long been a staple on the World Health Organization’s List of Essential Medicines.
Categories: Compounds used in a research, industrial, or household settingSynonyms: N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid, L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acidHepatitis B Vaccine (Recombinant)
go.drugbank.com/drugs/DB11627ApprovedInvestigationalWithdrawnHepatitis D virus, a defective virus requiring the “keeper function” of the hepatitis B virus, occurs either as a co-infection or super-infection in a HBsAg carrier. … Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada.
Mixtures: HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET, HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 10 ADETProducts: VACUNADE LA HEPATITIS B (RADN), ENGERIX-B SUSPENSION FOR INJECTION IN PREFILLED SYRINGE 20MCG/MLMethotrexate
go.drugbank.com/drugs/DB00563ApprovedInvestigational[A180322,L7144,L7147,L7150,L7180] Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and severe psoriasis only if first line treatment has failed or patients … Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis.
Categories: OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid, 4-amino-N(10)-methylpteroylglutamic acidInsulin human
go.drugbank.com/drugs/DB00030ApprovedInvestigationalIf left untreated, the body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening … Human insulin is also available in an inhalable form, intended to be used as a bolus meal-time insulin.
Mixtures: Humulin 10/90 Inj, Humulin 10/90 InjCategories: Drugs Used in DiabetesErythropoietin
go.drugbank.com/drugs/DB00016ApprovedInvestigationalErythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. … Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using recombinant DNA technology and is used for the treatment of patients with anemia associated with
Products: Binocrit 2,000 IU/1 ml solution for injection in a pre-filled syringe, Binocrit 10 000 IU/1 ml solution for injection in a pre-filled syringeThe Oncogenic Action of D-2-Hydroxyglutarate in Hydroxyglutaric aciduria
smpdb.ca/view/SMP0002359DiseaseThis results in modulations of HIF-mediated hypoxia responses and alterations in gene expression through global epigenetic remodelling that may contribute to malignant transformation. 2-Hydroxyglutarate … A mutation in IDH causes high concentrations of D-2-Hydroxyglutaric acid. D-2-hydroxyglutarate is a competitive inhibitor of 2OG-dependent dioxygenases resulting in genetic changes and malignancies.
Triptorelin
go.drugbank.com/drugs/DB06825ApprovedInvestigationalVet approvedAfter chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. … Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH).
Synonyms: (D-Trp6)-GnRH, pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2Products: Triptofem 0,1 mg/ml Injektionslösung in einer Fertigspritze, Decapeptyl Depot - Retardmikrokapseln und Suspensionsmittel in Einmalspritzen