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alpha-Tocopherol acetate
go.drugbank.com/drugs/DB14003ApprovedThe recommended dietary allowances (RDAs) for vitamin E alpha-tocopherol are: males = 4 mg (6 IU) females = 4 mg (6 IU) in ages 0-6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months … Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements.
Mixtures: Maxi 10 Tab, Fortamines 10 CapsulesCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesGlycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approved[L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and is considered to have a wider therapeutic window than [tiotropium]. … Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers.[L33110] They are both quaternary ammonium compounds and long acting muscarinic antagonists.
Mixtures: ENERZAIR BREEZHALER INHALATION POWDER, HARD CAPSULE 150 MCG /50 MCG /160 MCG, ULTIBRO BREEZHALER INHALATION POWDER HARD CAPSULE 110/50 MCGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesCytarabine
go.drugbank.com/drugs/DB00987ApprovedInvestigationalA pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specif...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: CYTARABINE 100 MG 10 AMPUL, ALEXAN 100 MG/5 ML.Eflepedocokin alfa
go.drugbank.com/drugs/DB16366InvestigationalEflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 human interleukin 22 (IL-22) molecules linked to an immunoglobulin constant … [A225706, L27661] It is being developed by Evive Biotech (previously known as Generon BioMed Inc).[L27666]
Synonyms: F-652 (RECOMBINANT FUSION PROTEIN CONSISTING OF TWO HUMAN INTERLEUKIN-22 (IL-22) MOLECULES LINKED TO AN IMMUNOGLOBULIN CONSTANT REGION (IGG2-FC))Ranitidine
go.drugbank.com/drugs/DB00863ApprovedWithdrawn[L10818,F4253] The prevalence of GERD is thought to be 10-20% in western countries. … This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of its ability to decrease gastric acid secretion.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: ULCURAN 50 MG 10 AMPUL, RANOBEL 50 MG/2 ML ENJEKTABL AMPUL, 100 ADETClarithromycin
go.drugbank.com/drugs/DB01211ApprovedInvestigationalClarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit.
Mixtures: TRIO 1000 MG + 500 MG + 30 MG TEDAVİ PAKETİ, 6X7 ADET, TRIO 1000 MG + 500 MG + 30 MG TEDAVİ PAKETİ, 6X14 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsDesmopressin
go.drugbank.com/drugs/DB00035ApprovedInvestigationalIt is considered a first-line therapy for central diabetes insipidus but is ineffective in patients with nephrogenic diabetes insipidus, where the kidneys are non-responsive to the hormone [A275458, L56105 … First synthesized in the 1960s, desmopressin has remained a gold-standard therapy for water balance disorders due to its safety and long duration of action compared to natural AVP [A31661, A275461].
Products: MINIRIN 0,1 MG TABLET, 100 ADET, MINIRIN 0,2 MG TABLET, 100 ADETPregabalin
go.drugbank.com/drugs/DB00230ApprovedInvestigational[L1006,L7066] It may have dependence liability if misused but the risk appears to be highest in patients with current or past substance use disorders.[A31161] … [A187190] Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects by binding to the α2δ subunit of voltage-dependent
Mixtures: PAGAMAX PLUS 150 MG/1 MG KAPSÜL ,60 KAPSÜL, PREPLUS B12 150 MG/1 MG EFERVESAN TABLET, 60 ADETProducts: REGABA 100 MG KAPSÜL,56 KAPSÜL, PIREPSIL 100 MG KAPSÜL, 56 ADETFluorouracil
go.drugbank.com/drugs/DB00544ApprovedInvestigationalIt interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Mixtures: Actikerall 5 mg/g + 100 mg/g Lösung zur Anwendung auf der Haut, VERRUTOL %0,5 + %10 DERİ ÇÖZELTİSİ (15 G)Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesMemantine
go.drugbank.com/drugs/DB01043ApprovedInvestigationalIn 2013, this number increased to 44 million. Almost doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and to 115 million by 2050 [F4366]. … Memantine blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability and excessive stimulation in Alzheimer's Disease [T556].
Mixtures: MEGINGO 10/50 MG EFERVESAN TABLET, 100 ADET, MEGINGO 20/50 MG EFERVESAN TABLET, 100 ADETCategories: Cytochrome P-450 CYP2A6 Inhibitors, Cytochrome P-450 CYP2B6 Inhibitors