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Displaying results 1701 - 1710 of 10000 in total
  1. Target

    TRAF2 and NCK-interacting protein kinase

    go.drugbank.com/bio_entities/BE0009399
    TargetHumans

    MAP4Ks act in parallel to and are partially redundant with STK3/MST2 and STK4/MST2 in the phosphorylation and activation of LATS1/2, and establish MAP4Ks as components of the expanded Hippo pathway (PubMed … Activator of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

    Polypeptides: TRAF2 and NCK-interacting protein kinase
  2. Target

    Multidrug and toxin extrusion protein 2

    go.drugbank.com/bio_entities/BE0004752
    TransporterHumans

    Plays a physiological role in the excretion of drugs, toxins and endogenous metabolites through the kidney … Mediates the efflux of endogenous compounds such as, creatinine, thiamine and estrone-3-sulfate.

    Polypeptides: Multidrug and toxin extrusion protein 2
  3. Drug

    Trifarotene

    go.drugbank.com/drugs/DB12808
    ApprovedInvestigational

    to vitamin A and are analogous only in function. … Trifarotene is a topical retinoid cream used in the treatment of acne vulgaris that was first approved for use in the United States in October 2019.

    Categories: Skin and Mucous Membrane Agents, Retinoids for Topical Use in AcneProducts: AKLIEF CREAM 50MCG/G
  4. Drug

    Pectin

    go.drugbank.com/drugs/DB11158
    ApprovedInvestigationalVet approved

    [L1961] The carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium salts or as acid amides. … Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants.[A32327] It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4.

    Mixtures: Kaolin and Pectin Susp, Cepacol Sore Throat and CoatingCategories: Compounds used in a research, industrial, or household setting, Alimentary Tract and Metabolism
  5. Drug

    Sodium oxybate

    go.drugbank.com/drugs/DB09072
    ApprovedInvestigational

    [L30598] It is a sodium salt of [gamma-Hydroxybutyric acid], an endogenous cerebral inhibitory neurotransmitter [A251445] and a metabolite of the inhibitory neurotransmitter GABA. … [L30598] An extended-release oral suspension formulation of sodium oxybate for narcolepsy, marketed under the brand name LUMRYZ, gained tentative FDA approval in July 2022 [L42645] and was fully approved

    Products: XYREM 500MG/ ML ORAL ÇÖZELTI
  6. Drug

    Urapidil

    go.drugbank.com/drugs/DB12661
    Investigational

    Urapidil has been investigated for the treatment of Hypertension During Pre-Eclampsia.

    Products: EBRANTIL 25MG IV ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL, AMPUL, 5 ADET, EBRANTIL 50MG IV ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL, AMPUL, 5 ADET
  7. Drug

    Estazolam

    go.drugbank.com/drugs/DB01215
    ApprovedIllicitInvestigational

    A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than diazepam or nitrazepam.

    Categories: Hypnotics and Sedatives, Benzodiazepine hypnotics and sedativesProducts: Prosom Tab 2mg
  8. Drug

    Carbamoylcholine

    go.drugbank.com/drugs/DB00411
    Approved

    Carbamoylcholine, also known as carbachol, is a muscarinic agonist discovered in 1932. … [A226315] Carbamoylcholine was initially used as a treatment for migraines,[A226365] induction of diuresis,[A226370] and other parasympathetic effects.

    Categories: Antiglaucoma Preparations and Miotics, Compounds used in a research, industrial, or household settingProducts: Carbachol Tab 2mg
  9. Drug

    Rifamycin

    go.drugbank.com/drugs/DB11753
    ApprovedInvestigationalWithdrawn

    [L4800] This drug was also sent for review to the EMA in 2015 by Dr. Falk Pharma Gmbh and it was granted a waiver for the tested conditions.[L4801] … [A39986] Rifamycin was further developed by Cosmo Technologies Ltd and approved in November 16, 2018 by the FDA as a prescription drug after being granted the designation of Qualified Infectious Disease

    Mixtures: RİF 250 MG/3 ML IM ENJEKSİYONLUK ÇÖZELTİ (1 AMPUL), RİF 250 MG/3 ML IM ENJEKSİYONLUK ÇÖZELTİ (100 AMPUL)Categories: Alimentary Tract and Metabolism
  10. Drug

    Rifapentine

    go.drugbank.com/drugs/DB01201
    ApprovedInvestigational

    Rifapentine is an antibiotic drug used in the treatment of tuberculosis. It inhibits DNA-dependent RNA polymerase activity in susceptible cells. … Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme.

    Products: PRIFTIN FILM COATED TABLETS 150MG